Rapid induction of androgen receptor splice variants by androgen deprivation in prostate cancer. (Q39647282)

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5 March 2020

title

Rapid induction of androgen receptor splice variants by androgen deprivation in prostate cancer (English)

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5 March 2020

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3

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5 March 2020

Changmeng Cai

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5 March 2020

author name string

Ziyang Yu

1

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5 March 2020

Sen Chen

2

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5 March 2020

Olga S Voznesensky

4

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5 March 2020

Elahe A Mostaghel

5

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5 March 2020

Peter S Nelson

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5 March 2020

Steven P Balk

8

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5 March 2020

language of work or name

English

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publication date

21 January 2014

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5 March 2020

published in

Clinical Cancer Research

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5 March 2020

volume

20

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issue

6

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5 March 2020

page(s)

1590-1600

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Mechanisms of the androgen receptor splicing in prostate cancer cells

5 March 2020

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Tyrosine kinase BMX phosphorylates phosphotyrosine-primed motif mediating the activation of multiple receptor tyrosine kinases

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ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer

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Androgen receptor splice variants are resistant to inhibitors of Hsp90 and FKBP52, which alter androgen receptor activity and expression

14 September 2017

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Androgen receptor splice variants mediate enzalutamide resistance in castration-resistant prostate cancer cell lines

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Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer.

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Androgen receptor splice variants activate androgen receptor target genes and support aberrant prostate cancer cell growth independent of canonical androgen receptor nuclear localization signal

14 September 2017

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AR intragenic deletions linked to androgen receptor splice variant expression and activity in models of prostate cancer progression

14 September 2017

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Effects of abiraterone acetate on androgen signaling in castrate-resistant prostate cancer in bone

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Androgen receptor variants occur frequently in castration resistant prostate cancer metastases

14 September 2017

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Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1.

14 September 2017

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Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors

14 September 2017

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Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: induction of steroidogenesis and androgen receptor splice variants

14 September 2017

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Alternatively spliced androgen receptor variants

14 September 2017

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Intratumoral androgen biosynthesis in prostate cancer pathogenesis and response to therapy

14 September 2017

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Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth

14 September 2017

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Abiraterone and increased survival in metastatic prostate cancer

14 September 2017

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Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer

14 September 2017

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Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance and short survival

14 September 2017

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Androgen receptor levels are upregulated by Akt in prostate cancer

14 September 2017

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Intragenic rearrangement and altered RNA splicing of the androgen receptor in a cell-based model of prostate cancer progression

14 September 2017

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Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor

14 September 2017

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Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Tyrosine kinase Etk/BMX is up-regulated in human prostate cancer and its overexpression induces prostate intraepithelial neoplasia in mouse

14 September 2017

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Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer

14 September 2017

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The androgen axis in recurrent prostate cancer

14 September 2017

1 reference

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Reactivation of androgen receptor-regulated TMPRSS2:ERG gene expression in castration-resistant prostate cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022291

Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer

14 September 2017

1 reference

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Development of the VCaP androgen-independent model of prostate cancer

14 September 2017

1 reference

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Suppression versus induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers.

14 September 2017

1 reference

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HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability

14 September 2017

1 reference

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10.1158/1078-0432.CCR-13-1863

21 August 2018

Identifiers

DOI

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5 March 2020

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5 March 2020

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