Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG. (Q39649952)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22353256%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22353256%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22353256%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Gary R. Mirams

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22353256%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Teun P de Boer

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22353256%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

author name string

Marc A Vos

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22353256%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Göran Duker

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22353256%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Peter Sartipy

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22353256%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Toon A B van Veen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22353256%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

publication date

14 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22353256%20AND%20SRC:MED&resulttype=core&format=json

Journal of Molecular and Cellular Cardiology

23 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22353256%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

volume

52

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22353256%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22353256%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

page(s)

998-1008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22353256%20AND%20SRC:MED&resulttype=core&format=json

Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes

23 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Modelling the long QT syndrome with induced pluripotent stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Quantified proarrhythmic potential of selected human embryonic stem cell-derived cardiomyocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Patient-specific induced pluripotent stem-cell models for long-QT syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Human embryonic stem cell-derived cardiomyocytes: demonstration of a portion of cardiac cells with fairly mature electrical phenotype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

The action potential and comparative pharmacology of stem cell-derived human cardiomyocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Progressive maturation in contracting cardiomyocytes derived from human embryonic stem cells: Qualitative effects on electrophysiological responses to drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Developmental changes in cardiomyocytes differentiated from human embryonic stem cells: a molecular and electrophysiological approach.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Mechanism of spontaneous excitability in human embryonic stem cell derived cardiomyocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

From first class to third class: recent upheaval in antiarrhythmic therapy--lessons from clinical trials

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Differences in action potential and early afterdepolarization properties in LQT2 and LQT3 models of long QT syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Use of preclinical assays to predict risk of drug-induced torsades de pointes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Molecular signature of cardiomyocyte clusters derived from human embryonic stem cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Inhibition of lysosomal degradation rescues pentamidine-mediated decreases of K(IR)2.1 ion channel expression but not that of K(v)11.1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Isolation and characterization of I(Kr) in cardiac myocytes by Cs+ permeation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

A computational model of the human left-ventricular epicardial myocyte

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Mathematical models of action potentials in the periphery and center of the rabbit sinoatrial node.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Contributions of HERG K+ current to repolarization of the human ventricular action potential

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

The CellML Model Repository

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

CELLULAR OPEN RESOURCE (COR): current status and future directions.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Increased short-term variability of repolarization predicts d-sotalol-induced torsades de pointes in dogs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

A hyperpolarization activated inward current (If) is present in infant ventricular myocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Pacemaker current (I(f)) in the human sinoatrial node.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Human cardiomyocyte progenitor cell-derived cardiomyocytes display a maturated electrical phenotype.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Effects of heart failure on brain-type Na+ channels in rabbit ventricular myocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Novel, ultraslow inactivating sodium current in human ventricular cardiomyocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Barium block of Kir2 and human cardiac inward rectifier currents: evidence for subunit-heteromeric contribution to native currents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Characteristics of the delayed rectifier current (IKr and IKs) in canine ventricular epicardial, midmyocardial, and endocardial myocytes. A weaker IKs contributes to the longer action potential of the M cell

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Antagonism by ranolazine of the pro-arrhythmic effects of increasing late INa in guinea pig ventricular myocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Probing the contribution of IKs to canine ventricular repolarization: key role for beta-adrenergic receptor stimulation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Use-dependent block of the pacemaker current I(f) in rabbit sinoatrial node cells by zatebradine (UL-FS 49). On the mode of action of sinus node inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Investigating dynamic protocol-dependence of hERG potassium channel inhibition at 37 degrees C: Cisapride versus dofetilide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Dog left ventricular midmyocardial myocytes for assessment of drug-induced delayed repolarization: short-term variability and proarrhythmic potential

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Comparison of the IKr blockers moxifloxacin, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals lack of specificity of isolated cardiomyocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

A mechanistic interpretation of the action of toxin II from Anemonia sulcata on the cardiac sodium channel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Na+ channel mutation leading to loss of function and non-progressive cardiac conduction defects.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Post-transcriptional silencing of SCN1B and SCN2B genes modulates late sodium current in cardiac myocytes from normal dogs and dogs with chronic heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

L-type calcium currents of human myocytes from ventricle of non-failing and failing hearts and from atrium.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Reverse rate-dependent changes are determined by baseline action potential duration in mammalian and human ventricular preparations.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

A model for early afterdepolarizations: induction with the Ca2+ channel agonist Bay K 8644.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Effects of the chromanol 293B, a selective blocker of the slow, component of the delayed rectifier K+ current, on repolarization in human and guinea pig ventricular myocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

I(Ks) restricts excessive beat-to-beat variability of repolarization during beta-adrenergic receptor stimulation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Cellular basis for the ECG features of the LQT1 form of the long-QT syndrome: effects of beta-adrenergic agonists and antagonists and sodium channel blockers on transmural dispersion of repolarization and torsade de pointes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

I(Kr) vs. I(Ks) blockade and arrhythmogenicity in normoxic rabbit Purkinje fibers: does it really make a difference?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Cardiomyocyte differentiation of mouse and human embryonic stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.02.002

10.1016/J.YJMCC.2012.02.002

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22353256%20AND%20SRC:MED&resulttype=core&format=json

release_6eq4wyszhre7fohg4aladrvjai

23 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/6eq4wyszhre7fohg4aladrvjai

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22353256%20AND%20SRC:MED&resulttype=core&format=json