HPMA copolymer-aminohexylgeldanamycin conjugates targeting cell surface expressed GRP78 in prostate cancer (Q39655348)

13 September 2017

title

HPMA copolymer-aminohexylgeldanamycin conjugates targeting cell surface expressed GRP78 in prostate cancer (English)

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13 September 2017

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Nate Larson

1

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13 September 2017

Abhijit Ray

2

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13 September 2017

Alexander Malugin

3

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13 September 2017

Daniel B Pike

4

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13 September 2017

Hamidreza Ghandehari

5

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13 September 2017

publication date

16 September 2010

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13 September 2017

published in

Pharmaceutical Research

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13 September 2017

volume

27

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13 September 2017

issue

12

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13 September 2017

page(s)

2683-2693

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Phase II studies of polymer-doxorubicin (PK1, FCE28068) in the treatment of breast, lung and colorectal cancer

13 September 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FS11095-010-0267-7

Influence of the structure of drug moieties on the in vitro efficacy of HPMA copolymer-geldanamycin derivative conjugates

21 January 2018

1 reference

12 December 2020

A phase II trial of 17-(Allylamino)-17-demethoxygeldanamycin in patients with papillary and clear cell renal cell carcinoma

1 reference

12 December 2020

The ER function BiP is a master regulator of ER function

1 reference

12 December 2020

Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal

1 reference

12 December 2020

Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies

1 reference

12 December 2020

Glucose depletion accounts for the induction of two transformation-sensitive membrane proteinsin Rous sarcoma virus-transformed chick embryo fibroblasts

1 reference

12 December 2020

Binding of activated alpha2-macroglobulin to its cell surface receptor GRP78 in 1-LN prostate cancer cells regulates PAK-2-dependent activation of LIMK

1 reference

12 December 2020

Surface properties of copolymers of alkyl methacrylates with methoxy (polyethylene oxide) methacrylates and their application as protein-resistant coatings.

1 reference

12 December 2020

Development of HPMA copolymer-anticancer conjugates: clinical experience and lessons learnt

1 reference

12 December 2020

Liberation of doxorubicin from HPMA copolymer conjugate is essential for the induction of cell cycle arrest and nuclear fragmentation in ovarian carcinoma cells

1 reference

12 December 2020

Heat shock protein 90 as a drug target: some like it hot.

1 reference

12 December 2020

Biodistribution of HPMA copolymer-aminohexylgeldanamycin-RGDfK conjugates for prostate cancer drug delivery

1 reference

12 December 2020

HPMA copolymers: origins, early developments, present, and future

1 reference

12 December 2020

Unilineage megakaryocytic proliferation and differentiation of purified hematopoietic progenitors in serum-free liquid culture

1 reference

12 December 2020

Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review

1 reference

12 December 2020

Activation and cross-talk between Akt, NF-kappaB, and unfolded protein response signaling in 1-LN prostate cancer cells consequent to ligation of cell surface-associated GRP78.

1 reference

12 December 2020

Geldanamycin, a HSP90 inhibitor, attenuates the hypoxia-induced vascular endothelial growth factor expression in retinal pigment epithelium cells in vitro

1 reference

12 December 2020

Polymeric conjugates of mono- and bi-cyclic alphaVbeta3 binding peptides for tumor targeting

1 reference

12 December 2020

Targetable water-soluble polymer-drug conjugates for the treatment of visceral leishmaniasis

1 reference

12 December 2020

Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands

1 reference

12 December 2020

N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers for targeted delivery of 8-aminoquinoline antileishmanial drugs

1 reference

12 December 2020

Cancer antineovascular therapy with liposome drug delivery systems targeted to BiP/GRP78.

1 reference

12 December 2020

Ansamycin inhibitors of Hsp90: nature's prototype for anti-chaperone therapy

1 reference

12 December 2020

Do HPMA copolymer conjugates have a future as clinically useful nanomedicines? A critical overview of current status and future opportunities.

1 reference

12 December 2020

Technetium-99m-Labeled N-(2-hydroxypropyl) methacrylamide copolymers: synthesis, characterization, and in vivo biodistribution

1 reference

12 December 2020

Spontaneous and controllable activation of suicide gene expression driven by the stress-inducible grp78 promoter resulting in eradication of sizable human tumors.

1 reference

12 December 2020

HPMA copolymer-cyclic RGD conjugates for tumor targeting

1 reference

12 December 2020

Preclinical pharmacologic evaluation of geldanamycin as an antitumor agent

1 reference

12 December 2020

Targetable HPMA copolymer-aminohexylgeldanamycin conjugates for prostate cancer therapy

1 reference

12 December 2020

Cell surface relocalization of the endoplasmic reticulum chaperone and unfolded protein response regulator GRP78/BiP.

1 reference

12 December 2020

The origin of pegnology

1 reference

12 December 2020

Effect of molecular weight (Mw) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats.

1 reference

12 December 2020

Polymeric drugs based on conjugates of synthetic and natural macromolecules. I. Synthesis and physico-chemical characterisation

1 reference

12 December 2020

Synthesis and characterization of HPMA copolymer-aminopropylgeldanamycin conjugates

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12 December 2020

Inhibitors of the HSP90 molecular chaperone: current status

1 reference

12 December 2020

HPMA copolymer-1,5-diazaanthraquinone conjugates as novel anticancer therapeutics

1 reference

12 December 2020

Geldanamycin and its anti-cancer activities

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12 December 2020

10.1007/S11095-010-0267-7

Identifiers

DOI

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13 September 2017

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