Cholera toxin and heat-labile enterotoxin activate human monocyte-derived dendritic cells and dominantly inhibit cytokine production through a cyclic AMP-dependent pathway. (Q39656632)

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scientific article published on October 2002

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English	Cholera toxin and heat-labile enterotoxin activate human monocyte-derived dendritic cells and dominantly inhibit cytokine production through a cyclic AMP-dependent pathway.	scientific article published on October 2002

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12228279%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

Cholera toxin and heat-labile enterotoxin activate human monocyte-derived dendritic cells and dominantly inhibit cytokine production through a cyclic AMP-dependent pathway (English)

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Europe PubMed Central

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13 November 2019

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Sayed F Abdelwahab

2

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13 November 2019

4

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13 November 2019

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Kenneth C Bagley

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13 November 2019

Robert G Tuskan

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13 November 2019

George K Lewis

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13 November 2019

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1 October 2002

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13 November 2019

Infection and Immunity

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13 November 2019

70

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13 November 2019

10

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13 November 2019

5533-5539

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13 November 2019

Genetically manipulated bacterial toxin as a new generation mucosal adjuvant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

14 September 2017

Cholera toxin suppresses interleukin (IL)-12 production and IL-12 receptor beta1 and beta2 chain expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

14 September 2017

Intranasal immunization with cytotoxic T-lymphocyte epitope peptide and mucosal adjuvant cholera toxin: selective augmentation of peptide-presenting dendritic cells in nasal mucosa-associated lymphoid tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

14 September 2017

Mutants in the ADP-ribosyltransferase cleft of cholera toxin lack diarrheagenicity but retain adjuvanticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

14 September 2017

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

14 September 2017

Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as nontoxic, mucosal adjuvants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

14 September 2017

Comparison of the carbohydrate-binding specificities of cholera toxin and Escherichia coli heat-labile enterotoxins LTh-I, LT-IIa, and LT-IIb

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

14 September 2017

Mechanism of adenylate cyclase activation by cholera toxin: Inhibition of GTP hydrolysis at the regulatory site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

14 September 2017

Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

14 September 2017

Cholera toxin B pretreatment of macrophages and monocytes diminishes their proinflammatory responsiveness to lipopolysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

25 September 2017

Modulation of innate and acquired immune responses by Escherichia coli heat-labile toxin: distinct pro- and anti-inflammatory effects of the nontoxic AB complex and the enzyme activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

25 September 2017

Structural basis for the differential toxicity of cholera toxin and Escherichia coli heat-labile enterotoxin. Construction of hybrid toxins identifies the A2-domain as the determinant of differential toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

25 September 2017

Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3',5'-cyclic phosphorothioates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

25 September 2017

Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

25 September 2017

Recombinant cholera toxin B subunit is not an effective mucosal adjuvant for oral immunization of mice against Helicobacter felis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

17 June 2018

Accumulating evidence suggests that several AB-toxins subvert the endoplasmic reticulum-associated protein degradation pathway to enter target cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

17 June 2018

Cholera toxin adjuvant promotes long-term immunological memory in the gut mucosa to unrelated immunogens after oral immunization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

17 June 2018

Induction of mucosal and systemic immune responses by intranasal immunization using recombinant cholera toxin B subunit as an adjuvant.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

21 August 2018

Mechanisms for mucosal immunogenicity and adjuvancy of Escherichia coli labile enterotoxin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

21 August 2018

Size and structure of the cholera toxin molecule and its subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=128358

21 August 2018

Enterotoxin adjuvants have direct effects on T cells and antigen-presenting cells that result in either interleukin-4-dependent or -independent immune responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/12228279

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholera toxin induces maturation of human dendritic cells and licences them for Th2 priming

1 reference

https://pubmed.ncbi.nlm.nih.gov/12228279

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of dendritic cell maturation and modulation of dendritic cell-induced immune responses by prostaglandins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12228279

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholera toxin: interaction of subunits with ganglioside GM1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12228279

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term cholera antitoxin memory in the gut can be triggered to antibody formation associated with protection within hours of an oral challenge immunization

1 reference

https://pubmed.ncbi.nlm.nih.gov/12228279

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effectiveness of cholera toxin B subunit as an adjuvant for nasal influenza vaccination despite pre-existing immunity to CTB

1 reference

https://pubmed.ncbi.nlm.nih.gov/12228279

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Helper Th1 and Th2 cell responses following mucosal or systemic immunization with cholera toxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12228279

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of cholera toxin adjuvanticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12228279

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic and mucosal immune responses of mice to aluminium-adsorbed or aluminium-non-adsorbed tetanus toxoid administered intranasally with recombinant cholera toxin B subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/12228279

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of GM1 binding in the mucosal immunogenicity and adjuvant activity of the Escherichia coli heat-labile enterotoxin and its B subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/12228279

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4

1 reference

https://pubmed.ncbi.nlm.nih.gov/12228279

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulating dendritic cells to optimize mucosal immunization protocols

1 reference

https://pubmed.ncbi.nlm.nih.gov/12228279

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/IAI.70.10.5533-5539.2002

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12228279%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12228279%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12228279%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

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