An Fgf/Gremlin inhibitory feedback loop triggers termination of limb bud outgrowth (Q39664464)

13 September 2017

An Fgf/Gremlin inhibitory feedback loop triggers termination of limb bud outgrowth (English)

1 reference

13 September 2017

Jamie M Verheyden

1

1 reference

13 September 2017

Xin Sun

series ordinal

2

1 reference

13 September 2017

language of work or name

English

0 references

publication date

25 June 2008

1 reference

13 September 2017

1 reference

13 September 2017

454

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13 September 2017

7204

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13 September 2017

638-641

1 reference

https://scigraph.springernature.com/pub.10.1038/nature07085

13 September 2017

0 references

cites work

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Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis

14 September 2017

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Regulation of Gremlin expression in the posterior limb bud.

14 September 2017

1 reference

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Increasing Fgf4 expression in the mouse limb bud causes polysyndactyly and rescues the skeletal defects that result from loss of Fgf8 function

14 September 2017

1 reference

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Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities

14 September 2017

1 reference

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Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840222

Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840222

Interplay between the molecular signals that control vertebrate limb development

14 September 2017

1 reference

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Functions of FGF signalling from the apical ectodermal ridge in limb development

14 September 2017

1 reference

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Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function

14 September 2017

1 reference

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Fgf8 is required for outgrowth and patterning of the limbs

14 September 2017

1 reference

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Measuring dimensions: the regulation of size and shape

14 September 2017

1 reference

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Control of vertebrate limb outgrowth by the proximal factor Meis2 and distal antagonism of BMPs by Gremlin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840222

The BMP antagonist Gremlin regulates outgrowth, chondrogenesis and programmed cell death in the developing limb

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840222

Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds.

14 September 2017

1 reference

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Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development

14 September 2017

1 reference

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Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed.

17 June 2018

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Cell proliferation in the attainment of constant sizes and shapes: the Entelechia model.

17 June 2018

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BMP signals control limb bud interdigital programmed cell death by regulating FGF signaling.

17 June 2018

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Model for the regulation of size in the wing imaginal disc of Drosophila

21 August 2018

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BMP receptor type IA in limb bud mesenchyme regulates distal outgrowth and patterning.

21 August 2018

1 reference

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The limb bud Shh-Fgf feedback loop is terminated by expansion of former ZPA cells.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840222

Fgf signaling controls the number of phalanges and tip formation in developing digits.

21 August 2018

1 reference

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The IIIc alternative of Fgfr2 is a positive regulator of bone formation.

21 August 2018

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Generation of Bmpr/Alk3 conditional knockout mice.

21 August 2018

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Fgf8 signalling from the AER is essential for normal limb development.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840222

BMPs negatively regulate structure and function of the limb apical ectodermal ridge.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840222

Differential regulation of gene expression in the digit forming area of the mouse limb bud by SHH and gremlin 1/FGF-mediated epithelial-mesenchymal signalling

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840222

Generation of Fgfr1 conditional knockout mice

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18594511

12 December 2020

inferred from PubMed ID database lookup

Bmp4 in limb bud mesoderm regulates digit pattern by controlling AER development

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18594511

12 December 2020

inferred from PubMed ID database lookup

Conditional inactivation of Fgfr1 in mouse defines its role in limb bud establishment, outgrowth and digit patterning.

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE07085

7 January 2021

inferred from DOI database lookup

Antagonistic interactions between FGF and BMP signaling pathways: a mechanism for positioning the sites of tooth formation

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE07085

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NATURE07085

1 reference

Dimensions Publication ID

13 September 2017

0 references

1 reference

13 September 2017

1 reference