Palmitoyl Ascorbate-Loaded Polymeric Micelles: Cancer Cell Targeting and Cytotoxicity (Q39664565)

13 September 2017

title

Palmitoyl ascorbate-loaded polymeric micelles: cancer cell targeting and cytotoxicity (English)

1 reference

13 September 2017

Palmitoyl Ascorbate-Loaded Polymeric Micelles: Cancer Cell Targeting and Cytotoxicity (English)

1 reference

https://api.crossref.org/works/10.1007/S11095-010-0242-3

21 June 2024

0 references

0 references

Onkar Vaze

2

1 reference

13 September 2017

Karen Rockwell

4

1 reference

13 September 2017

Rupa R. Sawant

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20730558

21 June 2024

Gerard G. M. D'Souza

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20730558

21 June 2024

Vladimir P. Torchilin

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20730558

21 June 2024

language of work or name

1 reference

21 August 2010

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full work available at URL

13 September 2017

http://link.springer.com/content/pdf/10.1007/s11095-010-0242-3.pdf

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1007/S11095-010-0242-3

http://link.springer.com/article/10.1007/s11095-010-0242-3/fulltext.html

21 June 2024

1 reference

https://api.crossref.org/works/10.1007/S11095-010-0242-3

http://link.springer.com/content/pdf/10.1007/s11095-010-0242-3

21 June 2024

1 reference

https://api.crossref.org/works/10.1007/S11095-010-0242-3

21 June 2024

published in

Pharmaceutical Research

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13 September 2017

volume

28

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13 September 2017

issue

2

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13 September 2017

page(s)

301-308

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Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer

13 September 2017

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21 January 2018

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Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues

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Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo

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Vitamin C crosses the blood-brain barrier in the oxidized form through the glucose transporters

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Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid

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Ascorbic acid increases drug accumulation and reverses vincristine resistance of human non-small-cell lung-cancer cells

21 January 2018

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Motexafin gadolinium generates reactive oxygen species and induces apoptosis in sensitive and highly resistant multiple myeloma cells

21 January 2018

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Pharmacologic concentrations of ascorbate are achieved by parenteral administration and exhibit antitumoral effects

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Solubilization of hydrophobic drugs in octanoyl-6-O-ascorbic acid micellar dispersions

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Ascorbyl palmitate vesicles (Aspasomes): formation, characterization and applications

21 January 2018

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Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review

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Surface modification of pharmaceutical nanocarriers with ascorbate residues improves their tumor-cell association and killing and the cytotoxic action of encapsulated paclitaxel in vitro

21 January 2018

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The in vitro cytotoxicity of ascorbate depends on the culture medium used to perform the assay and involves hydrogen peroxide

21 January 2018

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Micellar nanocarriers: pharmaceutical perspectives

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Lipid-core micelles for targeted drug delivery

21 January 2018

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Micelles from lipid derivatives of water-soluble polymers as delivery systems for poorly soluble drugs

21 January 2018

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Phase I clinical trial of i.v. ascorbic acid in advanced malignancy

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Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance

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Antiproliferative effect of ascorbic acid is associated with the inhibition of genes necessary to cell cycle progression

21 January 2018

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Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice

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PEG-PE/phosphatidylcholine mixed immunomicelles specifically deliver encapsulated taxol to tumor cells of different origin and promote their efficient killing

21 January 2018

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Mixed micelles made of poly(ethylene glycol)-phosphatidylethanolamine conjugate and d-alpha-tocopheryl polyethylene glycol 1000 succinate as pharmaceutical nanocarriers for camptothecin

21 January 2018

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Polyethylene glycol-phosphatidylethanolamine conjugate (PEG-PE)-based mixed micelles: some properties, loading with paclitaxel, and modulation of P-glycoprotein-mediated efflux

21 January 2018

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Solubilization of poorly soluble PDT agent, meso-tetraphenylporphin, in plain or immunotargeted PEG-PE micelles results in dramatically improved cancer cell killing in vitro

21 January 2018

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Effect of colloidal carriers on ascorbyl palmitate stability

21 January 2018

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Fluorescence microscopy to follow the targeting of liposomes and micelles to cells and their intracellular fate

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The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells

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Antioxidant enzyme levels in oral squamous cell carcinoma and normal human oral epithelium

21 January 2018

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Ascorbate potentiates the cytotoxicity of menadione leading to an oxidative stress that kills cancer cells by a non-apoptotic caspase-3 independent form of cell death

21 January 2018

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21 January 2018

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Effect of Ascorbic Acid and Its Hydrophobic Derivative Palmitoyl Ascorbate on the Redox State of Primary Human Fibroblasts

21 January 2018

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12 December 2020

Stromal cell oxidation: a mechanism by which tumors obtain vitamin C

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12 December 2020

Antioxidant enzyme levels in cancer

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12 December 2020

Ascorbic acid (vitamin C) improves the antineoplastic activity of doxorubicin, cisplatin, and paclitaxel in human breast carcinoma cells in vitro

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12 December 2020

Biology of free radical scavengers: an evaluation of ascorbate

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12 December 2020

Feasibility and correlates of arsenic trioxide combined with ascorbic acid-mediated depletion of intracellular glutathione for the treatment of relapsed/refractory multiple myeloma

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Polyethylene glycol-diacyllipid micelles demonstrate increased acculumation in subcutaneous tumors in mice

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12 December 2020

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12 December 2020

Does vitamin C act as a pro-oxidant under physiological conditions?

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12 December 2020

c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

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12 December 2020

Dehydroascorbic acid transport by GLUT4 in Xenopus oocytes and isolated rat adipocytes

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12 December 2020

Identifiers

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13 September 2017

1 reference