Role of tumor suppressor p53 domains in selective binding to supercoiled DNA. (Q39687338)

14 September 2017

Role of tumor suppressor p53 domains in selective binding to supercoiled DNA. (English)

1 reference

14 September 2017

7

Borivoj Vojtesek

1 reference

14 September 2017

Marie Brázdová

1

1 reference

14 September 2017

Jan Palecek

2

1 reference

14 September 2017

Dmitry I Cherny

3

1 reference

14 September 2017

Sabina Billová

4

1 reference

14 September 2017

Miroslav Fojta

5

1 reference

14 September 2017

Petr Pecinka

6

1 reference

14 September 2017

Thomas M Jovin

8

1 reference

14 September 2017

Emil Palecek

9

1 reference

14 September 2017

language of work or name

English

0 references

publication date

1 November 2002

1 reference

14 September 2017

Nucleic Acids Research

1 reference

14 September 2017

30

1 reference

14 September 2017

22

1 reference

14 September 2017

4966-4974

1 reference

Post-translational modifications and activation of p53 by genotoxic stresses

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

14 September 2017

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

p53 C-terminal interaction with DNA ends and gaps has opposing effect on specific DNA binding by the core

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Role of heteroduplex joints in the functional interactions between human Rad51 and wild-type p53.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Precise characterisation of monoclonal antibodies to the C-terminal region of p53 protein using the PEPSCAN ELISA technique and a new non-radioactive gel shift assay

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Specific modulation of p53 binding to consensus sequence within supercoiled DNA by monoclonal antibodies

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Maintenance of genomic integrity by p53: complementary roles for activated and non-activated p53.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Effect of transition metals on binding of p53 protein to supercoiled DNA and to consensus sequence in DNA fragments.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Regulation of p53 protein function through alterations in protein-folding pathways

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Covalent and noncovalent modifiers of the p53 protein

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Introduction: p53--the first twenty years

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Different regulation of the p53 core domain activities 3'-to-5' exonuclease and sequence-specific DNA binding

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

IARC Database of p53 gene mutations in human tumors and cell lines: updated compilation, revised formats and new visualisation tools

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Visualization of supercoiled DNA with atomic force microscopy in situ

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

The dihedral symmetry of the p53 tetramerization domain mandates a conformational switch upon DNA binding

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Eukaryotic topoisomerases recognize nucleic acid topology by preferentially interacting with DNA crossovers

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Local supercoil-stabilized DNA structures

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Analysis of p53 expression in human tumours: an antibody raised against human p53 expressed in Escherichia coli

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted alpha helices: crystal structure of the protein-DNA complex

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Regulation of the specific DNA binding function of p53

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Definition of a consensus binding site for p53

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

High affinity insertion/deletion lesion binding by p53. Evidence for a role of the p53 central domain

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Tumor suppressor protein p53 binds preferentially to supercoiled DNA.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Intramolecular synapsis of duplex DNA by vaccinia topoisomerase

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

The dimerization property of glutathione S-transferase partially reactivates Bcr-Abl lacking the oligomerization domain.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Formation of stable p53 homotetramers and multiples of tetramers

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Effects of Oxidation Agents and Metal Ions on Binding of p53 to Supercoiled DNA.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

p53 blocks RuvAB promoted branch migration and modulates resolution of Holliday junctions by RuvC.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Determination of glutathione-S-transferase traces in preparations of p53 C-terminal domain (aa320-393).

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

p53 Latency. C-terminal domain prevents binding of p53 core to target but not to nonspecific DNA sequences.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Binding of p53 and its core domain to supercoiled DNA.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Two distinct signaling pathways activate the latent DNA binding function of p53 in a casein kinase II-independent manner.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137164

Scanning force microscopy of the complexes of p53 core domain with supercoiled DNA

20 August 2018

1 reference

12 December 2020

Formation of large nucleoprotein complexes upon binding of the high-mobility-group (HMG) box B-domain of HMG1 protein to supercoiled DNA

1 reference

12 December 2020

Electron and scanning force microscopy studies of alterations in supercoiled DNA tertiary structure

1 reference

12 December 2020

Bacterial DNA topoisomerase I can relax positively supercoiled DNA containing a single-stranded loop

1 reference

12 December 2020

Effect of p53 protein redox states on binding to supercoiled and linear DNA

1 reference

12 December 2020

Preferential binding of tumor suppressor p53 to positively or negatively supercoiled DNA involves the C-terminal domain

1 reference

12 December 2020

Dissociation of the recombination control and the sequence-specific transactivation function of P53

1 reference

12 December 2020

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

1 reference

12 December 2020

DNA bending due to specific p53 and p53 core domain-DNA interactions visualized by electron microscopy

1 reference

12 December 2020

Human p53 binds Holliday junctions strongly and facilitates their cleavage

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKF616

1 reference

14 September 2017

1 reference

14 September 2017

PubMed publication ID

12434001

1 reference