Genotype-dependent effects of inhibitors of the organic cation transporter, OCT1: predictions of metformin interactions (Q39689968)

14 September 2017

title

Genotype-dependent effects of inhibitors of the organic cation transporter, OCT1: predictions of metformin interactions (English)

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14 September 2017

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G Ahlin

1

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14 September 2017

L Chen

2

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14 September 2017

L Lazorova

3

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14 September 2017

Y Chen

4

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14 September 2017

A G Ianculescu

5

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14 September 2017

R L Davis

6

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14 September 2017

K M Giacomini

7

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14 September 2017

P Artursson

8

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14 September 2017

publication date

22 June 2010

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The Pharmacogenomics Journal

14 September 2017

published in

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14 September 2017

volume

11

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14 September 2017

issue

6

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14 September 2017

page(s)

400-411

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Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines.

14 September 2017

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Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1

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Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action

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Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.

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Cloning and characterization of two human polyspecific organic cation transporters

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

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Clinical pharmacokinetics of metformin

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Comparison of the pharmacokinetics of glipizide and glibenclamide in man

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Finishing the euchromatic sequence of the human genome

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Amino acids critical for substrate affinity of rat organic cation transporter 1 line the substrate binding region in a model derived from the tertiary structure of lactose permease

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Cysteine accessibility in the hydrophilic cleft of human organic cation transporter 2.

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A global drug inhibition pattern for the human ATP-binding cassette transporter breast cancer resistance protein (ABCG2).

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Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics

21 January 2018

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Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus

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Reduced-function SLC22A1 polymorphisms encoding organic cation transporter 1 and glycemic response to metformin: a GoDARTS study

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Association between the number of coadministered P-glycoprotein inhibitors and serum digoxin levels in patients on therapeutic drug monitoring

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A human transporter protein that mediates the final excretion step for toxic organic cations

21 January 2018

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Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters

21 January 2018

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Polymorphism in human organic cation transporters and metformin action

21 January 2018

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Metformin transport by renal basolateral organic cation transporter hOCT2.

21 January 2018

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Structural determinants of inhibitor interaction with the human organic cation transporter OCT2 (SLC22A2).

21 January 2018

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Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2.

21 January 2018

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Genetic variation in the multidrug and toxin extrusion 1 transporter protein influences the glucose-lowering effect of metformin in patients with diabetes: a preliminary study

21 January 2018

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Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin.

21 January 2018

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Genetic variants in multidrug and toxic compound extrusion-1, hMATE1, alter transport function

21 January 2018

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Bioequivalence evaluation of two formulations of doxazosin tablet in healthy thai male volunteers

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/TPJ.2010.54

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release_zjtr6repwbg65docfzvylapica

14 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zjtr6repwbg65docfzvylapica

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference