Zinc released from injured cells is acting via the Zn2+-sensing receptor, ZnR, to trigger signaling leading to epithelial repair (Q39696868)

14 September 2017

Zinc released from injured cells is acting via the Zn2+-sensing receptor, ZnR, to trigger signaling leading to epithelial repair (English)

1 reference

14 September 2017

Haleli Sharir

1

1 reference

14 September 2017

Anna Zinger

2

1 reference

14 September 2017

Andrey Nevo

3

1 reference

14 September 2017

Israel Sekler

4

1 reference

14 September 2017

Michal Hershfinkel

5

1 reference

14 September 2017

language of work or name

English

0 references

publication date

3 June 2010

1 reference

Journal of Biological Chemistry

14 September 2017

1 reference

14 September 2017

285

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14 September 2017

34

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14 September 2017

26097-26106

1 reference

describes a project that uses

14 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2924011/fullTextXML

inferred from PubMed Central ID database lookup

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Zinc and skin health: overview of physiology and pharmacology

14 September 2017

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ATP-dependent paracrine intercellular communication in cultured bovine corneal endothelial cells

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1.

14 September 2017

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14 September 2017

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A zinc-sensing receptor triggers the release of intracellular Ca2+ and regulates ion transport

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Selective inhibition of mitogen-activated protein kinase phosphatases by zinc accounts for extracellular signal-regulated kinase 1/2-dependent oxidative neuronal cell death

14 September 2017

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Combined inhibition of MAPK and mTOR signaling inhibits growth, induces cell death, and abrogates invasive growth of melanoma cells

14 September 2017

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pH dependence of melanoma cell migration: protons extruded by NHE1 dominate protons of the bulk solution

14 September 2017

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G alpha(q/11)-coupled P2Y2 nucleotide receptor inhibits human keratinocyte spreading and migration.

14 September 2017

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Wound-induced ATP release and EGF receptor activation in epithelial cells

14 September 2017

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Mitogen-activated protein kinase-dependent activation of the Na+/H+ exchanger is mediated through phosphorylation of amino acids Ser770 and Ser771.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924011

Cannabinoid receptor agonist-induced apoptosis of human prostate cancer cells LNCaP proceeds through sustained activation of ERK1/2 leading to G1 cell cycle arrest

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924011

Protein kinase C (PKC)-delta/-epsilon mediate the PKC/Akt-dependent phosphorylation of extracellular signal-regulated kinases 1 and 2 in MCF-7 cells stimulated by bradykinin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924011

The extracellular zinc-sensing receptor mediates intercellular communication by inducing ATP release.

14 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924011

EGF receptor transactivation mediates ANG II-stimulated mitogenesis in intestinal epithelial cells through the PI3-kinase/Akt/mTOR/p70S6K1 signaling pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924011

Extracellular zinc triggers ERK-dependent activation of Na+/H+ exchange in colonocytes mediated by the zinc-sensing receptor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924011

Cellular injury induces activation of MAPK via P2Y receptors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924011

Na-H exchange-dependent increase in intracellular pH times G2/M entry and transition

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924011

Zinc, copper and manganese enhanced keratinocyte migration through a functional modulation of keratinocyte integrins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924011

Extracellular calcium stimulates DNA synthesis in synergism with zinc, insulin and insulin-like growth factor I in fibroblasts

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924011

Zinc deprivation of murine 3T3 cells by use of diethylenetrinitrilopentaacetate impairs DNA synthesis upon stimulation with insulin-like growth factor-1 (IGF-1).

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924011

Bombesin and zinc enhance the synergistic mitogenic effects of insulin and phosphocholine by a MAP kinase-dependent mechanism in Swiss 3T3 cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924011

Addition of zinc and manganese to a biological dressing

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924011

Cell death induced by zinc and cadmium is mediated by clusterin in cultured mouse seminiferous tubules

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924011

Zinc transporters and cancer: a potential role for ZIP7 as a hub for tyrosine kinase activation.

20 August 2018

1 reference

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A distinct role in breast cancer for two LIV-1 family zinc transporters.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924011

The human zinc transporter SLC39A8 (Zip8) is critical in zinc-mediated cytoprotection in lung epithelia

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924011

Extracellular zinc and zinc-citrate, acting through a putative zinc-sensing receptor, regulate growth and survival of prostate cancer cells

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924011

Airway epithelial cell migration and wound repair by ATP-mediated activation of dual oxidase 1.

20 August 2018

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Extracellular pH Controls NHE1 expression in epidermis and keratinocytes: implications for barrier repair

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924011

Modification of PI3K- and MAPK-dependent chemotaxis in aortic vascular smooth muscle cells by protein kinase CbetaII.

20 August 2018

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YM-254890 analogues, novel cyclic depsipeptides with Galpha(q/11) inhibitory activity from Chromobacterium sp. QS3666.

20 August 2018

1 reference

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Stimulation of the plasma membrane Na+/H+ exchanger NHE1 by sustained intracellular acidosis. Evidence for a novel mechanism mediated by the ERK pathway.

20 August 2018

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Improvement and biological applications of fluorescent probes for zinc, ZnAFs

20 August 2018

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Molecular and functional characterization of sodium--hydrogen exchanger in skin as well as cultured keratinocytes and melanocytes

20 August 2018

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Collagenase-2 (MMP-8) and matrilysin-2 (MMP-26) expression in human wounds of different etiologies

20 August 2018

1 reference

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MAPKAPK-2 Signaling Is Critical for Cutaneous Wound Healing

21 January 2018

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Transcriptional Signature of Epidermal Keratinocytes Subjected toin VitroScratch Wounding Reveals Selective Roles for ERK1/2, p38, and Phosphatidylinositol 3-Kinase Signaling Pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.107490

Transcriptional profiling defines the roles of ERK and p38 kinases in epidermal keratinocytes

21 January 2018

1 reference

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Zinc in the healing wound

21 January 2018

1 reference

12 December 2020

How do injured cells communicate with the surviving cell monolayer?

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12 December 2020

Non-invasive in vivo methods for investigation of the skin barrier physical properties

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12 December 2020

Effects of zinc deficient diet on development of atopic dermatitis-like eruptions in DS-Nh mice

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12 December 2020

Novel Zinc Fluorescent Probes Excitable with Visible Light for Biological Applications We thank Prof. E. Kimura and Prof. T. Koike for advice on the chemistry of macrocyclic polyamines

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12 December 2020

Fluorescence-based zinc ion sensor for zinc ion release from pancreatic cells

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12 December 2020

Roles of mitogen-activated protein kinases and protein kinase C in alpha(1A)-adrenoceptor-mediated stimulation of the sarcolemmal Na(+)-H(+) exchanger

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12 December 2020

Identifiers

DOI

10.1074/JBC.M110.107490

1 reference

14 September 2017

1 reference

14 September 2017

PubMed publication ID

20522546

1 reference