Cyclooxygenase-2 inhibitor NS398 enhances radiosensitivity of radioresistant esophageal cancer cells by inhibiting AKT activation and inducing apoptosis (Q39702048)

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English	Cyclooxygenase-2 inhibitor NS398 enhances radiosensitivity of radioresistant esophageal cancer cells by inhibiting AKT activation and inducing apoptosis	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Cyclooxygenase-2 inhibitor NS398 enhances radiosensitivity of radioresistant esophageal cancer cells by inhibiting AKT activation and inducing apoptosis (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

apoptotic process

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esophageal cancer

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based on heuristic

inferred from title

author name string

Shao-Min Che

1

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Xiao-Zhi Zhang

2

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Lei Hou

3

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Tian-Bao Song

4

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

publication date

1 August 2010

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Europe PubMed Central

PubMed publication ID

14 September 2017

Cancer Investigation

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Europe PubMed Central

PubMed publication ID

14 September 2017

28

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Europe PubMed Central

PubMed publication ID

14 September 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

679-688

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Europe PubMed Central

PubMed publication ID

14 September 2017

Multimodality treatment of esophageal cancer: a review of the current status and future directions

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Differential gene expression profiles of radioresistant oesophageal cancer cell lines established by continuous fractionated irradiation

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

COX-2 inhibitors as radiation sensitizers for upper GI tract cancers: esophagus, stomach, and pancreas

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Overexpression of cyclooxygenase-2 is associated with radioresistance in oral squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Significance of COX-2 expression in human esophageal squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Prognostic role of cyclooxygenase-2 expression in esophageal carcinoma.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Overexpression of cyclooxygenase-2 is associated with chemoradiotherapy resistance and prognosis in esophageal squamous cell carcinoma patients

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Expression of Cox-2 protein in radioresistant laryngeal cancer.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Mechanism of growth inhibitory effects of cyclooxygenase-2 inhibitor-NS398 on cancer cells

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

COX-2 mRNA expression in esophageal squamous cell carcinoma (ESCC) and effect by NSAID.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Anti-gastric cancer effects of celecoxib, a selective COX-2 inhibitor, through inhibition of Akt signaling

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Celecoxib, a cyclooxygenase-2 inhibitor, induces apoptosis in human osteosarcoma cell line MG-63 via down-regulation of PI3K/Akt

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

3-phosphoinositide-dependent protein kinase-1/Akt signaling represents a major cyclooxygenase-2-independent target for celecoxib in prostate cancer cells

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Celecoxib disrupts the canonical apoptotic network in HTLV-I cells through activation of Bax and inhibition of PKB/Akt

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Radiosensitivity enhancement by celecoxib, a cyclooxygenase (COX)-2 selective inhibitor, via COX-2-dependent cell cycle regulation on human cancer cells expressing differential COX-2 levels

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Cyclooxygenase-2 inhibitors demonstrate anti-proliferative effects in oesophageal cancer cells by prostaglandin E(2)-independent mechanisms

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

NS-398 induces apoptosis in human esophageal cancer cells through inhibition of NF-kappaB downstream regulation of cyclooxygenase-2.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Stress and radiation-induced activation of multiple intracellular signaling pathways

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Therapeutic potential of phosphoinositide 3-kinase inhibitors.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Combination of a COX-2 inhibitor with radiotherapy or radiochemotherapy in the treatment of thoracic cancer

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Radiation sensitivity of human carcinoma cells transfected with small interfering RNA targeted against cyclooxygenase-2.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Combination of radiation and celebrex (celecoxib) reduce mammary and lung tumor growth

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

COX-2 inhibitors act as radiosensitizer in tumor treatment.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Mechanism and regulation of human non-homologous DNA end-joining

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

The role of double-strand break repair — insights from human genetics

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Synergy between celecoxib and radiotherapy results from inhibition of cyclooxygenase-2-derived prostaglandin E2, a survival factor for tumor and associated vasculature

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Enhancement of glioblastoma radioresponse by a selective COX-2 inhibitor celecoxib: inhibition of tumor angiogenesis with extensive tumor necrosis

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Inhibition of COX-2 with NS-398 decreases colon cancer cell motility through blocking epidermal growth factor receptor transactivation: possibilities for combination therapy.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Systematic review: Cyclo-oxygenase-2 in human oesophageal adenocarcinogenesis.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

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10.3109/07357907.2010.483504

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

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https://api.fatcat.wiki/v0/release/ow526q3hjvfb3iro5wr6qx7hhe

24 November 2022

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PubMed publication ID

1 reference

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14 September 2017

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