Molybdenum hydroxylases: biological distribution and substrate-inhibitor specificity (Q39704403)

14 September 2017

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title

Molybdenum hydroxylases: biological distribution and substrate-inhibitor specificity (English)

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14 September 2017

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Beedham C

1

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PubMed ID

3332920

14 September 2017

language of work or name

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1 January 1987

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Progress in medicinal chemistry

14 September 2017

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14 September 2017

24

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14 September 2017

85-127

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Metabolic origins of the pyridones of N 1 -methylnicotinamide in man and rat

14 September 2017

1 reference

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7 January 2021

The identity of rabbit-liver methotrexate oxidase

1 reference

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7 January 2021

A comparison of the specificities of xanthine oxidase and aldehyde oxidase.

1 reference

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7 January 2021

Molybdenum hydroxylases as drug-metabolizing enzymes

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7 January 2021

EVIDENCE FOR SEMIQUINONE-METAL INTERACTION IN METAL-FLAVOPROTEINS

1 reference

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7 January 2021

Spin-spin interaction between molybdenum and one of the iron-sulphur systems of xanthine oxidase and its relevance to the enzymic mechanism

1 reference

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7 January 2021

Magnetic coupling of the molybdenum and iron-sulphur centres in xanthine oxidase and xanthine dehydrogenases

1 reference

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7 January 2021

Properties of the prosthetic groups of rabbit liver aldehyde oxidase: a comparison of molybdenum hydroxylase enzymes

1 reference

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7 January 2021

Magnetic interactions in milk xanthine oxidase

1 reference

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7 January 2021

Determination of the stoichiometry of electron uptake and the midpoint reduction potentials of milk xanthine oxidase at 25.degree. by microcoulometry

1 reference

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7 January 2021

Human liver aldehyde oxidase: differential inhibition of oxidation of charged and uncharged substrates

1 reference

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7 January 2021

Purification and properties of the NAD+-dependent (type D) and O2-dependent (type O) forms of rat liver xanthine dehydrogenase

1 reference

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7 January 2021

The regulation of rat liver xanthine oxidase. Involvement of thiol groups in the conversion of the enzyme activity from dehydrogenase (type D) into oxidase (type O) and purification of the enzyme

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7 January 2021

Xanthine oxidase activities: Evidence for two catalytically different types

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7 January 2021

Preparation of bovine milk xanthine oxidase as a dehydrogenase form

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7 January 2021

The mechanism of conversion of rat liver xanthine dehydrogenase from an NAD+-dependent form (type D) to an O2-dependent form (type O)

1 reference

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7 January 2021

Enzymic conversion of rat liver xanthine oxidase from dehydrogenase (D form) to oxidase (O form)

1 reference

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7 January 2021

Involvement of a single thiol group in the conversion of the NAD+-dependent activity of rat liver xanthine oxidoreductase to the O2-dependent activity

1 reference

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7 January 2021

Intermediate dehydrogenase-oxidase form of xanthine oxidoreductase in rat liver

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7 January 2021

Identification of hypoxanthine transport and xanthine oxidase activity in brain capillaries.

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7 January 2021

Xanthine oxidase: an enzyme playing a role in the killing mechanism of polymorphonuclear leucocytes

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7 January 2021

Bovine thyroidal xanthine oxidase

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7 January 2021

The oxidation of azaheterocycles with mammalian liver aldehyde oxidase

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7 January 2021

Primary deuterium isotope effect in the oxidation of an iminium ion by aldehyde oxidase.

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7 January 2021

Oxidation in H2O and D2O of 6-ethyl-5H-dibenz(c,e)azepine and 1-methylnicotinamide by aldehyde oxidase from rabbit liver

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7 January 2021

Simultaneous formation of 2- and 4-quinolones from quinolinium cations catalysed by aldehyde oxidase

1 reference

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7 January 2021

Specificity of xanthine oxidase for nitrogen heteroaromatic cation substrates

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7 January 2021

Xanthine oxidase in lentil (Lens esculenta) seedlings

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7 January 2021

The enzyme “aldehyde oxidase” is an iminium oxidase. Reaction with nicotine Δ1′(5′) iminium ion

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7 January 2021

The metabolism of nicotine-delta 1'(5')-iminium ion, in vivo and in vitro.

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7 January 2021

Properties of the xanthine oxidase from human liver.

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7 January 2021

Measurement of xanthine oxidase activity in some human tissues. An optimized method

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7 January 2021

Analysis of human alcohol- and aldehyde-metabolizing isozymes by electrophoresis and isoelectric focusing

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7 January 2021

Characteristics of membrane-bound and soluble forms of xanthine oxidase from milk and endothelial cells of capillaries

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7 January 2021

Liver aldehyde oxidase: the nature of hematin component

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7 January 2021

The fate of dibenz[b,f]-1,4-oxazepine (CR) in the rat. Part II. Metabolism in vitro

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7 January 2021

Immunological identification and determination of xanthine oxidase in cells and tissues

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7 January 2021

The lipoprotein particles in cow's milk

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7 January 2021

Liposomes as a proposed vehicle for the persorption of bovine xanthine oxidase

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7 January 2021

Studies on lymphatic absorption of and the availability of riboflavin from bovine milk xanthine oxidase

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7 January 2021

Studies on the Intestinal Absorption of Bovine Xanthine Oxidase

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7 January 2021

Xanthine oxidase in rabbit plasma after application of a bovine milk preparation to small intestine

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7 January 2021

Digestion and Absorption of Bovine Milk Xanthine Oxidase and its Role as an Aldehyde Oxidase

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7 January 2021

Homogenized Milk and Atherosclerotic Disease: A Review

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7 January 2021

Purification and characterization of the intestinal promoter of iron(3+)-transferrin formation

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7 January 2021

Genetics, ontogeny, and testosterone inducibility of aldehyde oxidase isozymes in the mouse: Evidence for two genetic loci (Aox-1 and Aox-2) closely linked on chromosome 1

1 reference

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7 January 2021

Milk xanthine oxidase type D (dehydrogenase) and type O (oxidase). Purification, interconversion and some properties

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7 January 2021

Association of xanthine oxidase with the bovine milk-fat-globule membrane

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7 January 2021

Formation and disposition of 7-hydroxymethotrexate in rabbits

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7 January 2021

The species distribution of xanthine oxidase

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7 January 2021

Combined Use of Radioenzymatic Assay and High Pressure Liquid Chromatography for the Detection of Myocardial Xanthine Oxidase/Dehydrogenase

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7 January 2021

Localization of xanthine oxidase in mammary-gland epithelium and capillary endothelium

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7 January 2021

Secretion of purines by the small intestine: general characteristics

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7 January 2021

The Influx of Uric Acid and other Purines into Everted Jejunal Sacs of the Rat and Hamster

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7 January 2021

Evidence for the participation of intestinal xanthine oxidase in the mucosal processing of iron

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7 January 2021

Studies of the ferroxidase activity of native and chemically modified xanthine oxidoreductase

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7 January 2021

Intestinal absorption and metabolism of 6-mercaptopurine in the rat small intestine

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7 January 2021

Clinical pharmacologic observations on 6-mercaptopurine and 6-methylthiopurine ribonucleoside

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7 January 2021

Variable bioavailability of oral mercaptopurine. Is maintenance chemotherapy in acute lymphoblastic leukemia being optimally delivered?

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7 January 2021

Metabolic disposition of acyclovir in the guinea pig, rabbit, and monkey

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7 January 2021

The xanthine oxidase activity of rat tissues

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7 January 2021

Xanthine oxidase activity in the brain

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7 January 2021

High concentrations of antibodies to xanthine oxidase in human and animal sera. Molecular characterization

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7 January 2021

Human serum xanthine oxidase: Fluorometric assay applicable to the investigation of liver disorders

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7 January 2021

Production of uric acid and existence of xanthine oxidase in rat plasma

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7 January 2021

Xanthine oxidase increase in polymorphonuclear leucocytes and macrophages in mice in three pathological situations.

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7 January 2021

Liver xanthine oxidase increase in mice in three patholgoical models. A possible defence mechanism.

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7 January 2021

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7 January 2021

Thyroid xanthine oxidase and its role in thyroid iodine metabolism in the rat: difference between effects of allopurinol and tungstate

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7 January 2021

Distribution of xanthine oxidase and xanthine dehydrogenase specificity types among bacteria

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7 January 2021

The relative toxicites of methotrexate and aminopterin

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7 January 2021

Identification and quantitation of methotrexate and methotrexate metabolites in clinical high-dose therapy by high pressure liquid chromatography and field desorption mass spectrometry

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7 January 2021

Species differences in the disposition of acyclovir

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7 January 2021

A species difference in the presystemic metabolism of carbazeran in dog and man

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7 January 2021

Oxidative metabolism of carbazeran in vitro by liver cytosol of baboon and man.

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7 January 2021

Aldehyde oxidase: catalysis of the oxidation of N 1 -methylnicotinamide and pyridoxal.

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7 January 2021

Alternate putrescine metabolites: quantitative analysis of delta'-pyrroline oxidation to 2-pyrrolidone in tissue homogenates by high-pressure liquid chromatography

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7 January 2021

Hydroxylation of 4-amino-antifolates by partially purified aldehyde oxidase from rabbit liver

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7 January 2021

7-Hydroxymethotrexate as a urinary metabolite in human subjects and rhesus monkeys receiving high dose methotrexate

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7 January 2021

The role of 7-hydroxymethotrexate during methotrexate anti-cancer therapy

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7 January 2021

The pharmacokinetics of 7-hydroxymethotrexate following medium-dose methotrexate therapy

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7 January 2021

7-Hydroxy-methotrexate and clinical toxicity following high-dose methotrexate therapy

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7 January 2021

Tight binding inhibitors of xanthine oxidase

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7 January 2021

The xanthine oxidase-aldehyde system

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7 January 2021

Studies on the specificity toward aldehyde substrates and steady-state kinetics of xanthine oxidase

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7 January 2021

The specificity of xanthine oxidase

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7 January 2021

The purification and properties of aldehyde oxidase

1 reference

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7 January 2021

Remarkable positional (regio)specificity of xanthine oxidase and some dehydrogenases in the reactions with substituted benzaldehydes

1 reference

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7 January 2021

Cyclophosphamide potentiation and aldehyde oxidase inhibition by phosphorylated aldehydes and acetals

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7 January 2021

Inhibition of xanthine oxidase by various aldehydes

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7 January 2021

2-Amino-4hydroxy-6-formylpteridine, an inhibitor of purine and pterine oxidases

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7 January 2021

Metabolism of acridine by rat-liver enzymes.

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7 January 2021

Identification of the metabolites of benzo[f]quinoline and benzo[h]quinoline formed by rat liver homogenate

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7 January 2021

An extremely potent anilinoacridine inhibitor of aldehyde oxidase.

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7 January 2021

Oxidation of hypoxanthines, bearing 8-aryl or 8-pyridyl substituents, by bovine milk xanthine oxidase

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7 January 2021

Defined dimensional changes in enzyme substrates and cofactors. Synthesis of lin-benzoadenosine and enzymatic evaluation of derivatives of the benzopurines

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7 January 2021

Irreversible enzyme inhibitors. 93. Hydrophobic bonding to xanthine oxidase by some phenylpurines

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7 January 2021

Irreversible Enzyme Inhibitors. CII. On the Mode of Phenyl Binding of 9-Phenylguanine to Guanine Deaminase and Xanthine Oxidase1-4

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7 January 2021

Irreversible enzyme inhibitors. CXXVI. Hydrocarbon interaction with xanthine oxidase by phenyl substituents on purines and pyrazolo[3,4-d]pyrimidines

1 reference

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7 January 2021

The antitumor and mammalian xanthine oxidase inhibitory activity of 5-methyl-6-substituted pyrrolo(2,3-d)pyrimidine-2,4-diones

1 reference

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7 January 2021

Effects of Allopurinol and Oxipurinol on Pyrimidine Biosynthesis in Man

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7 January 2021

Selective inhibition of xanthine oxidase by 3-hydroxy-1-nitrophenyl-1H-pyrazolo(4,3-c)pyridines

1 reference

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7 January 2021

3-Hydroxy-1-nitrophenyl-1(H-pyrazolo(3,4-b)pyridines as selective inhibitors of rat liver xanthine oxidase

1 reference

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7 January 2021

Synthesis and enzymic activity of some novel xanthine oxidase inhibitors. 3-Substituted 5,7-dihydroxypyrazolo[1,5-a]pyrimidines

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7 January 2021

3,5-disubstituted 1,2,3,4-triazoles, 1 new class of xanthine oxidase inhibitor

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7 January 2021

4-Trifluoromethylimidazoles and 5-(4-pyridyl)-1,2,4-triazoles, new classes of xanthine oxidase inhibitors

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7 January 2021

The location of the reactive carbon in N1-methylnicotinamide

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7 January 2021

Oxidation of N-methyl substituted hypoxanthines, xanthines, purine-6,8-diones and the corresponding 6-thioxo derivatives by bovine milk xanthine oxidase

1 reference

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7 January 2021

Methylated 7-deazahypoxanthines as regiochemical probes of xanthine oxidase

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7 January 2021

Behavior of N-methylated allopurinols and related 4-thioxopyrazolo [] pyrimidines towards bovine milk xanthine oxidase

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7 January 2021

Isomeric N-methyl-7-deazaguanines: synthesis, structural assignment, and inhibitory activity on xanthine oxidase

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7 January 2021

Oxidation of Selected Pteridine Derivatives by Mammalian Liver Xanthine Oxidase and Aldehyde Oxidase

1 reference

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7 January 2021

Pteridines as substrates of mammalian xanthine oxidase. II. Pathways and rates of oxidation

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7 January 2021

Oxidation of methyl derivatives of pteridin-4-one, lumazine and related pteridines by bovine milk xanthine oxidase

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7 January 2021

2,4-Dihydroxypteridine as an intermediate in the enzymically catalyzed oxidation of 4-hydroxypteridine

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7 January 2021

Tropylium tetrafluoroborate, a novel substrate for aldehyde oxidase

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7 January 2021

Oxidation of phenazine methosulfate by hepatic aldehyde oxidase

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7 January 2021

Reaction of 1-amino- and 1-chlorophthalazine with mammalian molybdenum hydroxylases in vitro

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7 January 2021

The effect of organic acids on renal clearance of methotrexate in man

1 reference

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7 January 2021

Studies of the metabolism of methotrexate by intestinal flora. I. Identification and study of biological properties of the metabolite 4-amino-4-deoxy-N 10 -methylpteroic acid

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7 January 2021

Enzymatic synthesis of polyglutamate derivatives of 7-hydroxymethotrexate

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7 January 2021

Inhibition of buttermilk xanthine oxidase by folate analogues and derivatives

1 reference

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7 January 2021

Studies of the oxidation of some aminopteridines by xanthine oxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970420-X

7 January 2021

XANTHINE AS A PRECURSOR OF NUCLEIC ACID PURINES IN THE MOUSE

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970420-X

7 January 2021

Clinicobiochemical analysis of four cases of xanthine oxidase deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970420-X

7 January 2021

Allopurinol metabolism in a patient with xanthine oxidase deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970420-X

7 January 2021

Oxidation of vitamin A1 aldehyde and vitamin A2 aldehyde to the corresponding acids by aldehyde oxidase from different species

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970420-X

7 January 2021

Metabolism of vitamin B-6 by human liver

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970420-X

7 January 2021

The metabolism of small doses of vitamin B-6 in men.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970420-X

7 January 2021

Biological role of xanthine oxidase and tetrazolium-reductase inhibitor.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970420-X

7 January 2021

Metabolism of phenanthridine to phenanthridone by rat lung and liver microsomes after induction with benzo[a]pyrene and aroclor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970420-X

7 January 2021

Elevation of molybdenum hydroxylase levels in rabbit liver after ingestion of phthalazine or its hydroxylated metabolite

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970420-X

7 January 2021

Hydralazine: a potent inhibitor of aldehyde oxidase activity in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970420-X

7 January 2021

6-Deoxyacyclovir: a xanthine oxidase-activated prodrug of acyclovir

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970420-X

7 January 2021

10.1016/S0079-6468(08)70420-X

Identifiers

DOI

0 references

PubMed ID

3332920

1 reference

PubMed ID

3332920