Discovery of N-[(4R)-6-(4-chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-4-yl]-5-methyl-1H-pyrazole-3-carboxamide (MK-5596) as a novel cannabinoid-1 receptor (CB1R) inverse agonist for the treatment of obesity (Q39710299)
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English | Discovery of N-[(4R)-6-(4-chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-4-yl]-5-methyl-1H-pyrazole-3-carboxamide (MK-5596) as a novel cannabinoid-1 receptor (CB1R) inverse agonist for the treatment of obesity |
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Discovery of N-[(4R)-6-(4-chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-4-yl]-5-methyl-1H-pyrazole-3-carboxamide (MK-5596) as a novel cannabinoid-1 receptor (CB1R) inverse agonist for the treatment of obesity (English)
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Alison M Strack
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Tung M Fong
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Lauren P Shearman
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Lin Yan
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Pei Huo
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John S Debenham
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Christina B Madsen-Duggan
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Julie Lao
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Richard Z Chen
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Jing Chen Xiao
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Chun-Pyn Shen
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D Sloan Stribling
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Nancy Tsou
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Richard G Ball
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Junying Wang
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Xinchun Tong
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Thomas J Bateman
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Vijay B G Reddy
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Jeffrey J Hale
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1 May 2010
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53
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10
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4028-4037
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Identifiers
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