Downregulation of XPF-ERCC1 enhances cisplatin efficacy in cancer cells. (Q39711077)

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1 February 2020

title

Downregulation of XPF-ERCC1 enhances cisplatin efficacy in cancer cells (English)

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1 February 2020

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1

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1 February 2020

author name string

Anbarasi Kothandapani

2

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1 February 2020

Kristin Tillison

3

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1 February 2020

Vivian Kalman-Maltese

4

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1 February 2020

Steve M Patrick

5

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publication date

24 April 2010

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1 February 2020

volume

9

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issue

7

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page(s)

745-753

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Interstrand crosslink repair: can XPF-ERCC1 be let off the hook?

1 February 2020

cites work

1 reference

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The HhH domain of the human DNA repair protein XPF forms stable homodimers

14 September 2017

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Enhanced repair of DNA interstrand crosslinking in ovarian cancer cells from patients following treatment with platinum-based chemotherapy

14 September 2017

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First reported patient with human ERCC1 deficiency has cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failure

14 September 2017

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DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy

14 September 2017

1 reference

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XPA versus ERCC1 as chemosensitising agents to cisplatin and mitomycin C in prostate cancer cells: role of ERCC1 in homologous recombination repair

14 September 2017

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Molecular mechanisms of mammalian global genome nucleotide excision repair.

14 September 2017

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The structure of the human ERCC1/XPF interaction domains reveals a complementary role for the two proteins in nucleotide excision repair

14 September 2017

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Regulation of DNA repair gene expression in human cancer cell lines

14 September 2017

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ABCC5, ERCC2, XPA and XRCC1 transcript abundance levels correlate with cisplatin chemoresistance in non-small cell lung cancer cell lines

14 September 2017

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The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks

14 September 2017

1 reference

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Reduced levels of XPA, ERCC1 and XPF DNA repair proteins in testis tumor cell lines.

14 September 2017

1 reference

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Growth retardation, early death, and DNA repair defects in mice deficient for the nucleotide excision repair enzyme XPF

14 September 2017

1 reference

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ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes

14 September 2017

1 reference

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Nucleotide excision repair- and polymerase eta-mediated error-prone removal of mitomycin C interstrand cross-links

14 September 2017

1 reference

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DNA repair and cisplatin resistance in non-small-cell lung cancer

14 September 2017

1 reference

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Defects in interstrand cross-link uncoupling do not account for the extreme sensitivity of ERCC1 and XPF cells to cisplatin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4331052

Repair of DNA interstrand crosslinks: molecular mechanisms and clinical relevance.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4331052

The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4331052

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4331052

Repair of an interstrand DNA cross-link initiated by ERCC1-XPF repair/recombination nuclease.

14 September 2017

1 reference

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4331052

Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4331052

In vitro and in vivo resistance to cisplatin in cells that have lost DNA mismatch repair

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4331052

Reconstitution of human excision nuclease with recombinant XPF-ERCC1 complex

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4331052

Repair of cisplatin--DNA adducts by the mammalian excision nuclease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4331052

Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4331052

Co-correction of the ERCC1, ERCC4 and xeroderma pigmentosum group F DNA repair defects in vitro

14 September 2017

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A simple technique for quantitation of low levels of DNA damage in individual cells

14 September 2017

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Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay

14 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4331052

RAD10, an excision repair gene of Saccharomyces cerevisiae, is involved in the RAD1 pathway of mitotic recombination

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4331052

The ERCC1/XPF endonuclease is required for completion of homologous recombination at DNA replication forks stalled by inter-strand cross-links

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4331052

Kinetics of H2AX phosphorylation after exposure to cisplatin

14 September 2017

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Endogenous expression of phosphorylated histone H2AX in tumors in relation to DNA double-strand breaks and genomic instability.

14 September 2017

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Small interfering RNA-induced suppression of ERCC1 enhances sensitivity of human cancer cells to cisplatin.

14 September 2017

1 reference

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Modulation of DNA repair in vitro after treatment with chemotherapeutic agents by the epidermal growth factor receptor inhibitor gefitinib (ZD1839).

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4331052

Enhanced cisplatin cytotoxicity by disturbing the nucleotide excision repair pathway in ovarian cancer cell lines.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4331052

Cisplatin and DNA repair in cancer chemotherapy

14 September 2017

1 reference

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Cellular responses to cisplatin. The roles of DNA-binding proteins and DNA repair

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4331052

Nucleotide excision repair genes as determinants of cellular sensitivity to cyclophosphamide analogs

25 September 2017

1 reference

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Expression measurement of many genes simultaneously by quantitative RT-PCR using standardized mixtures of competitive templates.

25 September 2017

1 reference

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Sustained activation of p53 in confluent nucleotide excision repair-deficient cells resistant to ultraviolet-induced apoptosis.

15 June 2018

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Excision repair cross-complementation group 1 predicts progression-free and overall survival in non-small cell lung cancer patients treated with platinum-based chemotherapy.

20 August 2018

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XPF nuclease-dependent telomere loss and increased DNA damage in mice overexpressing TRF2 result in premature aging and cancer.

20 August 2018

1 reference

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Biophysical characterization of the interaction domains and mapping of the contact residues in the XPF-ERCC1 complex.

20 August 2018

1 reference

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Low ERCC1 expression correlates with prolonged survival after cisplatin plus gemcitabine chemotherapy in non-small cell lung cancer.

20 August 2018

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Association between the level of ERCC-1 expression and the repair of cisplatin-induced DNA damage in human ovarian cancer cells.

20 August 2018

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Platinum-DNA adduct, nucleotide excision repair and platinum based anti-cancer chemotherapy.

20 August 2018

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Effect of ERCC1 polymorphisms and the modification by smoking on the survival of non-small cell lung cancer patients

20 August 2018

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12 December 2020

ERCC1 measurements in clinical oncology

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12 December 2020

The cloned human DNA excision repair gene ERCC-1 fails to correct xeroderma pigmentosum complementation groups A through I

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12 December 2020

Sensitive detection of DNA modifications induced by cisplatin and carboplatin in vitro and in vivo using a monoclonal antibody

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12 December 2020

Measurement of DNA cross-linking in patients on ifosfamide therapy using the single cell gel electrophoresis (comet) assay

1 reference

12 December 2020

ERCC1 and non-small-cell lung cancer

1 reference

12 December 2020

10.1016/J.DNAREP.2010.03.010

Identifiers

DOI

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1 February 2020

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