Pyruvate suppresses PGC1alpha expression and substrate utilization despite increased respiratory chain content in C2C12 myotubes (Q39712123)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20410436%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

Pyruvate suppresses PGC1alpha expression and substrate utilization despite increased respiratory chain content in C2C12 myotubes (English)

1 reference

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31 January 2020

1

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31 January 2020

Joaquín Pérez-Schindler

2

1 reference

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31 January 2020

Charlotte J Green

3

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31 January 2020

David Hamilton

4

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31 January 2020

author name string

Keith Baar

5

1 reference

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31 January 2020

language of work or name

1 reference

21 April 2010

1 reference

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American Journal of Physiology - Cell Physiology

31 January 2020

published in

1 reference

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31 January 2020

volume

299

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31 January 2020

issue

2

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31 January 2020

page(s)

C240-50

1 reference

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Calmodulin-dependent protein kinase kinase-beta activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP.

31 January 2020

cites work

1 reference

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Skeletal muscle "mitochondrial deficiency" does not mediate insulin resistance

14 September 2017

1 reference

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Short hairpin RNA-mediated silencing of PRC (PGC-1-related coactivator) results in a severe respiratory chain deficiency associated with the proliferation of aberrant mitochondria

14 September 2017

1 reference

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The role of exercise and PGC1alpha in inflammation and chronic disease

14 September 2017

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PGC-1alpha integrates insulin signaling, mitochondrial regulation, and bioenergetic function in skeletal muscle

14 September 2017

1 reference

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Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt

14 September 2017

1 reference

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Transcriptional paradigms in mammalian mitochondrial biogenesis and function

14 September 2017

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14 September 2017

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The PPARdelta agonist, GW501516, promotes fatty acid oxidation but has no direct effect on glucose utilisation or insulin sensitivity in rat L6 skeletal muscle cells

14 September 2017

1 reference

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Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation

14 September 2017

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14 September 2017

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Etiology of insulin resistance

14 September 2017

1 reference

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Involvement of PPAR gamma co-activator-1, nuclear respiratory factors 1 and 2, and PPAR alpha in the adaptive response to endurance exercise

14 September 2017

1 reference

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PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

14 September 2017

1 reference

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Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle

14 September 2017

1 reference

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Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres

14 September 2017

1 reference

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14 September 2017

1 reference

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Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells

14 September 2017

1 reference

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Lactate sensitive transcription factor network in L6 cells: activation of MCT1 and mitochondrial biogenesis.

14 September 2017

1 reference

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Control of mitochondrial biogenesis during myogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928631

Pyruvate induces mitochondrial biogenesis by a PGC-1 alpha-independent mechanism

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928631

Muscle-specific expression of PPARgamma coactivator-1alpha improves exercise performance and increases peak oxygen uptake

17 June 2018

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Exercise-induced attenuation of obesity, hyperinsulinemia, and skeletal muscle lipid peroxidation in the OLETF rat.

20 August 2018

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PGC-1alpha is not mandatory for exercise- and training-induced adaptive gene responses in mouse skeletal muscle.

20 August 2018

1 reference

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Effects of four-week high-fructose diet on gene expression in skeletal muscle of healthy men.

20 August 2018

1 reference

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Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency.

20 August 2018

1 reference

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Exercise increases nuclear AMPK alpha2 in human skeletal muscle.

20 August 2018

1 reference

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Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1.

20 August 2018

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Palmitate-mediated downregulation of peroxisome proliferator-activated receptor-gamma coactivator 1alpha in skeletal muscle cells involves MEK1/2 and nuclear factor-kappaB activation

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20410436

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20410436

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fluxing the mitochondria to insulin resistance

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20410436

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1152/AJPCELL.00438.2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20410436%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20410436%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

PubMed publication ID

20410436

1 reference