Structure-based quantitative structure--activity relationship modeling of estrogen receptor β-ligands (Q39735325)

14 September 2017

Structure-based quantitative structure--activity relationship modeling of estrogen receptor β-ligands (English)

1 reference

14 September 2017

Xialan Dong

1

1 reference

PubMed ID

21707397

14 September 2017

Solomon G Hilliard

series ordinal

2

1 reference

PubMed ID

21707397

14 September 2017

Weifan Zheng

series ordinal

3

1 reference

14 September 2017

1 June 2011

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Future Medicinal Chemistry

14 September 2017

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14 September 2017

3

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14 September 2017

8

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14 September 2017

933-945

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New selective estrogen receptor modulators (SERMs) in development

14 September 2017

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Reflections on the discovery and significance of estrogen receptor beta

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Evaluation of an Estrogen Receptor-β Agonist in Animal Models of Human Disease

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ERbeta ligands. Part 1: the discovery of ERbeta selective ligands which embrace the 4-hydroxy-biphenyl template

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ERbeta ligands. Part 2: Synthesis and structure-activity relationships of a series of 4-hydroxy-biphenyl-carbaldehyde oxime derivatives

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ERbeta ligands. Part 4: Synthesis and structure-activity relationships of a series of 2-phenylquinoline derivatives

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ERbeta ligands. Part 5: synthesis and structure-activity relationships of a series of 4'-hydroxyphenyl-aryl-carbaldehyde oxime derivatives

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Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 4: functionalization of the benzopyran A-ring

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Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 5: Combined A- and C-ring structure-activity relationship studies

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A comparative QSAR study using CoMFA, HQSAR, and FRED/SKEYS paradigms for estrogen receptor binding affinities of structurally diverse compounds.

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The importance of molecular structures, endpoints' values, and predictivity parameters in QSAR research: QSAR analysis of a series of estrogen receptor binders

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Pharmacophore and QSAR modeling of estrogen receptor beta ligands and subsequent validation and in silico search for new hits.

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Structure-based approach for the study of estrogen receptor binding affinity and subtype selectivity.

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Estrogen receptor β ligands: recent advances and biomedical applications.

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Activation of estrogen receptor-beta regulates hippocampal synaptic plasticity and improves memory

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A novel structure-based multimode QSAR method affords predictive models for phosphodiesterase inhibitors.

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Rational selection of training and test sets for the development of validated QSAR models

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ART 2: self-organization of stable category recognition codes for analog input patterns.

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On two novel parameters for validation of predictive QSAR models.

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Benchmarking sets for molecular docking

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Novel approach to structure-based pharmacophore search using computational geometry and shape matching techniques

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LigandScout: 3-D pharmacophores derived from protein-bound ligands and their use as virtual screening filters

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Endocrine therapy of breast cancer

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Receptor-based 3D QSAR analysis of estrogen receptor ligands--merging the accuracy of receptor-based alignments with the computational efficiency of ligand-based methods

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21 January 2018

Identifiers

DOI

10.4155/FMC.11.49

1 reference

14 September 2017

1 reference

PubMed ID

21707397