Dual gene therapy with SERCA1 and Kir2.1 abbreviates excitation without suppressing contractility (Q39737461)

14 September 2017

Dual gene therapy with SERCA1 and Kir2.1 abbreviates excitation without suppressing contractility (English)

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14 September 2017

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1

Irene L Ennis

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14 September 2017

Ronald A Li

2

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14 September 2017

Anne M Murphy

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3

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14 September 2017

Eduardo Marbán

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4

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14 September 2017

H Bradley Nuss

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5

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14 September 2017

language of work or name

English

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publication date

1 February 2002

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Journal of Clinical Investigation

14 September 2017

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14 September 2017

109

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14 September 2017

3

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14 September 2017

393-400

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Distinct gene-specific mechanisms of arrhythmia revealed by cardiac gene transfer of two long QT disease genes, HERG and KCNE1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150851

Molecular dissection of cardiac repolarization by in vivo Kv4.3 gene transfer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150851

Prospects for gene therapy for heart failure

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150851

Avoidance of immune response prolongs expression of genes delivered to the adult rat myocardium by replication-defective adenovirus

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150851

Sudden death prevention in patients with advanced ventricular dysfunction

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150851

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150851

Electrical constants of trabecular muscle from mammalian heart

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150851

Two types of calcium channels in guinea pig ventricular myocytes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150851

Construction of adenovirus vectors through Cre-lox recombination

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150851

Adenovirus-mediated inducible gene expression in vivo by a hybrid ecdysone receptor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150851

Comparison of SERCA1 and SERCA2a expressed in COS-1 cells and cardiac myocytes

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150851

Inward rectification and implications for cardiac excitability

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150851

Ca(2+)-currents and intracellular [Ca2+]i-transients in single ventricular myocytes isolated from terminally failing human myocardium

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150851

Reversal of potassium channel deficiency in cells from failing hearts by adenoviral gene transfer: a prototype for gene therapy for disorders of cardiac excitability and contractility

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150851

Ionic mechanism of action potential prolongation in ventricular myocytes from dogs with pacing-induced heart failure

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150851

Diverse mechanisms of unexpected cardiac arrest in advanced heart failure

17 June 2018

1 reference

12 December 2020

Electrophysiologic substrate associated with pacing-induced heart failure in dogs: Potential value of programmed stimulation in predicting sudden death

1 reference

12 December 2020

Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure

1 reference

12 December 2020

Triggered activity and automaticity in ventricular trabeculae of failing human and rabbit hearts

1 reference

12 December 2020

Inducible genetic suppression of neuronal excitability

1 reference

12 December 2020

Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, I: experimental studies

1 reference

12 December 2020

Manipulation of cellular excitability by cell fusion: effects of rapid introduction of transient outward K+ current on the guinea pig action potential

1 reference

12 December 2020

Exogenous Ca2+-ATPase isoform effects on Ca2+ transients of embryonic chicken and neonatal rat cardiac myocytes

1 reference

12 December 2020

Monoclonal antibodies to the Ca2+ + Mg2+-dependent ATPase of sarcoplasmic reticulum identify polymorphic forms of the enzyme and indicate the presence in the enzyme of a classical high-affinity Ca2+ binding site

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI0213359

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14 September 2017

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14 September 2017

PubMed publication ID

11827999

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