Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy (Q39739155)

14 September 2017

Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy (English)

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14 September 2017

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Sean M Armour

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14 September 2017

Joseph A Baur

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Sherry N Hsieh

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Abigail Land-Bracha

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Sheila M Thomas

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David A Sinclair

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3 June 2009

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515-528

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describes a project that uses

14 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2806030/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

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Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9

14 September 2017

1 reference

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Longevity mutation in SCH9 prevents recombination errors and premature genomic instability in a Werner/Bloom model system.

14 September 2017

1 reference

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Resveratrol stimulates AMP kinase activity in neurons

14 September 2017

1 reference

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Potential therapeutic applications of autophagy

14 September 2017

1 reference

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ATG1, an autophagy regulator, inhibits cell growth by negatively regulating S6 kinase

14 September 2017

1 reference

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

14 September 2017

1 reference

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Resveratrol improves health and survival of mice on a high-calorie diet

14 September 2017

1 reference

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Increased Rheb-TOR signaling enhances sensitivity of the whole organism to oxidative stress

14 September 2017

1 reference

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Resveratrol--a boon for treating Alzheimer's disease?

14 September 2017

1 reference

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Therapeutic potential of resveratrol: the in vivo evidence

14 September 2017

1 reference

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Another way to die: autophagic programmed cell death

14 September 2017

1 reference

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Autophagy in metazoans: cell survival in the land of plenty

14 September 2017

1 reference

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Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons.

14 September 2017

1 reference

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Autophagy in health and disease: a double-edged sword

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

14 September 2017

1 reference

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Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

14 September 2017

1 reference

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Regulation and role of autophagy in mammalian cells

14 September 2017

1 reference

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Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

Small molecules that regulate lifespan: evidence for xenohormesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

Role and regulation of starvation-induced autophagy in the Drosophila fat body

14 September 2017

1 reference

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Sirtuin activators mimic caloric restriction and delay ageing in metazoans

14 September 2017

1 reference

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Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

14 September 2017

1 reference

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Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

Development by self-digestion: molecular mechanisms and biological functions of autophagy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

Autophagy in the eukaryotic cell

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

Cancer chemopreventive activity of resveratrol, a natural product derived from grapes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

NAD depletion by FK866 induces autophagy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

Delivery of cytoplasmic proteins to autophagosomes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

Resveratrol inhibits glucose metabolism in human ovarian cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

Resveratrol-induced autophagocytosis in ovarian cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

The inhibition of phosphatidylinositol 3-kinase by quercetin and analogs

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

Identifying the estrogen receptor coactivator PELP1 in autophagosomes.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

The Ras and Sch9 pathways regulate stress resistance and longevity

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

Resveratrol inhibits phorbol ester and UV-induced activator protein 1 activation by interfering with mitogen-activated protein kinase pathways.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

Lipid oxidation and autophagy in yeast

2 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806030

Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20157535

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/AGING.100056

0 references

1 reference

14 September 2017

1 reference