Clinical pharmacokinetics of the cyclooxygenase inhibiting nitric oxide donator (CINOD) AZD3582. (Q39739399)

14 September 2017

title

Clinical pharmacokinetics of the cyclooxygenase inhibiting nitric oxide donator (CINOD) AZD3582. (English)

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14 September 2017

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Urban Fagerholm

1

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14 September 2017

Marcus A Björnsson

series ordinal

2

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14 September 2017

language of work or name

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1 December 2005

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Journal of Pharmacy and Pharmacology

14 September 2017

published in

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14 September 2017

volume

57

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14 September 2017

issue

12

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14 September 2017

page(s)

1539-1554

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Characterization of jejunal absorption and apical efflux of ropivacaine, lidocaine and bupivacaine in the rat using in situ and in vitro absorption models

14 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Gastrointestinal toxic side effects of nonsteroidal anti-inflammatory drugs and cyclooxygenase-2-specific inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Identification of the enzymatic mechanism of nitroglycerin bioactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Evaluation of using dog as an animal model to study the fraction of oral dose absorbed of 43 drugs in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Clinical pharmacokinetics of naproxen

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Comparison between permeability coefficients in rat and human jejunum

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Pre-clinical pharmacokinetics of the cyclooxygenase-inhibiting nitric oxide donor (CINOD) AZD3582.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Moderate dietary salt restriction increases vascular and systemic insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Clinical economics review: gastrointestinal complications of non-steroidal anti-inflammatory drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Gastrointestinal safety of AZD3582, a cyclooxygenase inhibiting nitric oxide donator: proof of concept study in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Drug binding in plasma. A summary of recent trends in the study of drug and hormone binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Haemoglobin: NO transporter, NO inactivator or NOne of the above?

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Renal effects of the cyclooxygenase-inhibiting nitric oxide donator AZD3582 compared with rofecoxib and naproxen during normal and low sodium intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Automated covariate model building within NONMEM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Nitric oxide metabolism and breakdown.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Interactions of human organic anion transporters and human organic cation transporters with nonsteroidal anti-inflammatory drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

A randomised, placebo controlled, comparative trial of the gastrointestinal safety and efficacy of AZD3582 versus naproxen in osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Man versus beast: pharmacokinetic scaling in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

The integrated response of the cardiovascular system to food

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

COX-2 selective inhibitors: analysis of the renal effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Relative risk of upper gastrointestinal complications among users of acetaminophen and nonsteroidal anti-inflammatory drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Absorption, Distribution, Metabolism, and Excretion of Naproxen in Various Laboratory Animals and Human Subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Pharmacokinetics of nitrate in humans: role of gastrointestinal absorption and metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Biological and metabolic study of naproxen-propyphenazone mutual prodrug

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Mechanisms of action of nitrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Effects of changing liver blood flow by exercise and food on kinetics and dynamics of saruplase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Short-term inhibitory effects of nitric oxide on cytochrome P450-mediated drug metabolism: time dependency and reversibility profiles in isolated perfused rat livers

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Nonsteroidal anti-inflammatory drugs and gastroenteropathy: the second hundred years

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Nonsteroidal anti-inflammatory drugs and the gastrointestinal tract. Mechanisms of protection and healing: current knowledge and future research

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Renal aspects of treatment with conventional nonsteroidal anti-inflammatory drugs versus cyclooxygenase-2-specific inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Cyclooxygenase and nitric oxide systems in the gut as therapeutic targets for safer anti-inflammatory drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

The "high solubility" definition of the current FDA Guidance on Biopharmaceutical Classification System may be too strict for acidic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2FJPP.57.12.0004

21 January 2018

Identifiers

DOI

10.1211/JPP.57.12.0004

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14 September 2017

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