IL-12 is required for differentiation of pathogenic CD8+ T cell effectors that cause myocarditis. (Q39741074)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12618521%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

IL-12 is required for differentiation of pathogenic CD8+ T cell effectors that cause myocarditis (English)

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1 November 2019

3

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1 November 2019

Ferhaan Ahmad

6

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1 November 2019

7

Christine E Seidman

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1 November 2019

author name string

Nir Grabie

1

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1 November 2019

Michael W Delfs

2

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1 November 2019

Victoria A Love

4

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1 November 2019

George Stavrakis

5

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1 November 2019

Jonathan G Seidman

8

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1 November 2019

Andrew H Lichtman

9

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1 November 2019

language of work or name

English

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publication date

1 March 2003

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Journal of Clinical Investigation

1 November 2019

published in

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1 November 2019

volume

111

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1 November 2019

page(s)

671-680

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1 November 2019

issue

5

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The transition from viral to autoimmune myocarditis

1 November 2019

cites work

1 reference

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Expression of immunoregulatory cytokines by recombinant coxsackievirus B3 variants confers protection against virus-caused myocarditis

14 September 2017

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Linking immune-mediated arterial inflammation and cholesterol-induced atherosclerosis in a transgenic mouse model

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Interleukin 12 protects from a T helper type 1-mediated autoimmune disease, experimental autoimmune uveitis, through a mechanism involving interferon gamma, nitric oxide, and apoptosis.

14 September 2017

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Interleukin 12 and interleukin 4 control T cell adhesion to endothelial selectins through opposite effects on alpha1, 3-fucosyltransferase VII gene expression

14 September 2017

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Generation of mucosal cytotoxic T cells against soluble protein by tissue-specific environmental and costimulatory signals.

14 September 2017

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CD4+ T cell help impairs CD8+ T cell deletion induced by cross-presentation of self-antigens and favors autoimmunity

14 September 2017

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Class I-restricted cross-presentation of exogenous self-antigens leads to deletion of autoreactive CD8(+) T cells

14 September 2017

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Constitutive class I-restricted exogenous presentation of self antigens in vivo

14 September 2017

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T cell receptor antagonist peptides induce positive selection

14 September 2017

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Antibodies to interleukin 12 abrogate established experimental colitis in mice

14 September 2017

1 reference

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Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12.

14 September 2017

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The role of CD8+ T lymphocytes in coxsackievirus B3-induced myocarditis

14 September 2017

1 reference

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Induction of ovalbumin-specific cytotoxic T cells by in vivo peptide immunization

14 September 2017

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14 September 2017

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14 September 2017

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Effects of IL-12 on immune responses to microbial infections: a key mediator in regulating disease outcome

14 September 2017

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14 September 2017

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25 September 2017

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25 September 2017

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15 June 2018

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Peptide antigen priming of naive, but not memory, CD8 T cells requires a third signal that can be provided by IL-12.

20 August 2018

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Interleukin-12 receptor/STAT4 signaling is required for the development of autoimmune myocarditis in mice by an interferon-gamma-independent pathway.

20 August 2018

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Susceptibility to myocarditis is dependent on the response of alphabeta T lymphocytes to coxsackieviral infection

20 August 2018

1 reference

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Recombinant murine interleukin-12 facilitates induction of cardiac myosin-specific type 1 helper T cells in rats.

20 August 2018

1 reference

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Coxsackievirus-induced myocarditis is dependent on distinct immunopathogenic responses in different strains of mice

20 August 2018

1 reference

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The tyrosine kinase p56lck is essential in coxsackievirus B3-mediated heart disease

20 August 2018

1 reference

12 December 2020

Cardiac myosin-induced myocarditis: target recognition by autoreactive T cells requires prior activation of cardiac interstitial cells

1 reference

12 December 2020

Reduced incidence and severity of collagen-induced arthritis in interleukin-12-deficient mice

1 reference

12 December 2020

Type 1 and type 2 CD8+ effector T cell subpopulations promote long-term tumor immunity and protection to progressively growing tumor

1 reference

12 December 2020

IL-12-independent Th1-type immune responses to respiratory viral infection: requirement of IL-18 for IFN-gamma release in the lung but not for the differentiation of viral-reactive Th1-type lymphocytes

1 reference

12 December 2020

Expression of intestine-specific antigen reveals novel pathways of CD8 T cell tolerance induction

1 reference

12 December 2020

CD8+ T cell subsets TC1 and TC2 cause different histopathologic forms of murine cardiac allograft rejection

1 reference

12 December 2020

Il-12 enhances CD8 T cell homeostatic expansion

1 reference

12 December 2020

Dual role of the IL-12/IFN-gamma axis in the development of autoimmune myocarditis: induction by IL-12 and protection by IFN-gamma

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI200316867

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12618521%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12618521%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference