DNA adducts by N-nitroso compounds (Q39746016)

14 September 2017

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title

DNA adducts by N-nitroso compounds (English)

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14 September 2017

M Wiessler

1

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14 September 2017

publication date

1 January 1986

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Journal of Cancer Research and Clinical Oncology

14 September 2017

published in

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14 September 2017

volume

112

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issue

2

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page(s)

81-84

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O4-ethyldeoxythymidine, but not O6-ethyldeoxyguanosine, accumulates in hepatocyte DNA of rats exposed continuously to diethylnitrosamine

14 September 2017

cites work

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12 December 2020

Differential repair of O4-alkylthymidine following exposure to methylating and ethylating hepatocarcinogens

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12 December 2020

Sites and thermodynamic quantities associated with proton and metal ion interaction with ribonucleic acid, deoxyribonucleic acid, and their constituent bases, nucleosides, and and nucleotides

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12 December 2020

Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats.

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12 December 2020

Biochemical significance of the hard and soft acids and bases principle

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12 December 2020

Reaction of N-n-butyl-N-nitrosourea with DNA in vitro

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12 December 2020

n-Propyldiazonium ion alkylates O6 of guanine with rearrangement, but alkylates N-7 without rearrangement

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12 December 2020

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12 December 2020

Specificity in carcinogen-DNA interaction: a theoretical exploration of the factors involved in the effect of neighboring bases on N-methyl-N-nitrosourea alkylation of DNA.

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12 December 2020

Methylation of the O6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents.

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12 December 2020

Extent of formation of O4-methylthymidine in calf thymus DNA methylated by N-methyl-N-nitrosourea and lack of repair of this product by rat liver O6-alkylguanine-DNA-alkyltransferase.

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12 December 2020

Effects of modifying structure on electrophilic reactions with biological nucleophiles

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12 December 2020

Repair of O6-methylguanine, by mammalian cell extracts, in alkylated DNA and poly(dG-m5dC).(poly dG-m5dC) in B and Z forms.

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12 December 2020

Repair of O6-propylguanine and O6-butylguanine in DNA by O6-alkylguanine-DNA alkyltransferases from rat liver and E. coli

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12 December 2020

Mechanism of alkylation by N-nitroso compounds: detection of rearranged alcohol in the microsomal metabolism of N-nitrosodi-n-propylamine and base-catalyzed decomposition of N-n-propyl-N-nitrosourea

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12 December 2020

Characterization of the purine ring-opened 7-methylguanine and its persistence in rat bladder epithelial DNA after treatment with the carcinogen N-methylnitrosourea.

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12 December 2020

Formation of cyclic 1,N2--adducts by reaction of deoxyguanosine with alpha-acetoxy-N-nitrosopyrrolidine, 4-(carbethoxynitrosamino)butanal, or crotonaldehyde.

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12 December 2020

Alkylation of the O6 of guanine is only one of many chemical events that may initiate carcinogenesis

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12 December 2020

DNA sequence has an effect on the extent and kinds of alkylation of DNA by a potent carcinogen

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12 December 2020

Mutagenic properties of N-cyclopropyl and N-allyl-N-nitroso compounds. Studies on the nature of alkylating species

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12 December 2020

In vitro reaction of N-n-butyl-N-nitrosourea and n-butyl methanesulphonate with guanine and thymine bases of DNA

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12 December 2020

O4-Methyl, -ethyl, or -isopropyl substituents on thymidine in poly(dA-dT) all lead to transitions upon replication

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12 December 2020

Mechanisms of carcinogenesis induced by alkylating agents

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12 December 2020

Identifiers

DOI

10.1007/BF00404386

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14 September 2017

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