The Toll-like receptor 2 (TLR2) ligand FSL-1 is internalized via the clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR2. (Q39746263)

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English	The Toll-like receptor 2 (TLR2) ligand FSL-1 is internalized via the clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR2.	scientific article

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17 January 2020

The Toll-like receptor 2 (TLR2) ligand FSL-1 is internalized via the clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR2 (English)

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17 January 2020

toll-like receptor

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2

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17 January 2020

author name string

Haque M Shamsul

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17 January 2020

Mitsuhiro Iyori

3

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17 January 2020

Makoto Ohtani

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17 January 2020

Kazuto Kiura

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17 January 2020

Diya Zhang

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17 January 2020

Yasunori Totsuka

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17 January 2020

Ken-ichiro Shibata

8

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17 January 2020

publication date

27 January 2010

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17 January 2020

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17 January 2020

130

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17 January 2020

2

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17 January 2020

262-272

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17 January 2020

The N-terminal lipopeptide of a 44-kDa membrane-bound lipoprotein of Mycoplasma salivarium is responsible for the expression of intercellular adhesion molecule-1 on the cell surface of normal human gingival fibroblasts

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2009.03232.X

21 January 2018

Involvement of Leucine Residues at Positions 107, 112, and 115 in a Leucine-Rich Repeat Motif of Human Toll-Like Receptor 2 in the Recognition of Diacylated Lipoproteins and Lipopeptides and Staphylococcus aureus Peptidoglycans

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2009.03232.X

21 January 2018

Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2009.03232.X

21 January 2018

TLR2 is mobilized into an apical lipid raft receptor complex to signal infection in airway epithelial cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2009.03232.X

21 January 2018

Antagonistic antibody prevents toll-like receptor 2-driven lethal shock-like syndromes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2009.03232.X

21 January 2018

Not lipoteichoic acid but lipoproteins appear to be the dominant immunobiologically active compounds in Staphylococcus aureus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2009.03232.X

21 January 2018

A dipalmitoylated lipoprotein from Mycoplasma pneumoniae activates NF-kappa B through TLR1, TLR2, and TLR6.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2009.03232.X

21 January 2018

Resveratrol modulates phagocytosis of bacteria through an NF-kappaB-dependent gene program

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14 October 2018

Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide

1 reference

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14 October 2018

CD36: implications in cardiovascular disease

1 reference

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14 October 2018

Clathrin-dependent mechanisms of G protein-coupled receptor endocytosis

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14 October 2018

The diacylated lipopeptide FSL-1 enhances phagocytosis of bacteria by macrophages through a Toll-like receptor 2-mediated signalling pathway

1 reference

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14 October 2018

Signalling and phagocytosis in the orchestration of host defence

1 reference

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14 October 2018

Inflammatory lipoproteins purified from a toxigenic and arthritogenic strain of Mycoplasma arthritidis are dependent on Toll-like receptor 2 and CD14.

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14 October 2018

Evidence of immunostimulating lipoprotein existing in the natural lipoteichoic acid fraction

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14 October 2018

Translational mini-review series on Toll-like receptors: networks regulated by Toll-like receptors mediate innate and adaptive immunity

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14 October 2018

The diacylated lipopeptide FSL-1 induces TLR2-mediated Th2 responses.

1 reference

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14 October 2018

Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting

1 reference

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14 October 2018

CD14 directly binds to triacylated lipopeptides and facilitates recognition of the lipopeptides by the receptor complex of Toll-like receptors 2 and 1 without binding to the complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878470

14 October 2018

Roles of N-linked glycans in the recognition of microbial lipopeptides and lipoproteins by TLR2.

1 reference

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14 October 2018

Pathogen recognition and innate immunity

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14 October 2018

Virus entry: open sesame

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14 October 2018

The synthetic analogue of mycoplasmal lipoprotein FSL-1 induces dendritic cell maturation through Toll-like receptor 2.

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14 October 2018

Listeria hijacks the clathrin-dependent endocytic machinery to invade mammalian cells

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14 October 2018

Response to Staphylococcus aureus requires CD36-mediated phagocytosis triggered by the COOH-terminal cytoplasmic domain

1 reference

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14 October 2018

Chemokine receptor internalization and intracellular trafficking

1 reference

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14 October 2018

Binding of lipopeptide to CD14 induces physical proximity of CD14, TLR2 and TLR1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878470

14 October 2018

CD36 is a sensor of diacylglycerides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878470

14 October 2018

Lipoteichoic acid and toll-like receptor 2 internalization and targeting to the Golgi are lipid raft-dependent

1 reference

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14 October 2018

Relationship between structures and biological activities of mycoplasmal diacylated lipopeptides and their recognition by toll-like receptors 2 and 6

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14 October 2018

Lipid rafts and caveolae as portals for endocytosis: new insights and common mechanisms

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14 October 2018

Regulated portals of entry into the cell

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14 October 2018

Alkyl-lysophospholipid accumulates in lipid rafts and induces apoptosis via raft-dependent endocytosis and inhibition of phosphatidylcholine synthesis

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14 October 2018

Stomatin is a major lipid-raft component of platelet alpha granules

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14 October 2018

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14 October 2018

Toll-like receptors as sensors of pathogens

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14 October 2018

Innate immunity

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14 October 2018

Acute cholesterol depletion inhibits clathrin-coated pit budding

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14 October 2018

Transcriptional activation of mRNA of intercellular adhesion molecule 1 and induction of its cell surface expression in normal human gingival fibroblasts by Mycoplasma salivarium and Mycoplasma fermentans

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Effects of cytokines on mycobacterial phagosome maturation

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Isolation, structure elucidation, and synthesis of a macrophage stimulatory lipopeptide from Mycoplasma fermentans acting at picomolar concentration

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14 October 2018

Adherence, fibronectin binding, and induction of cytoskeleton reorganization in cultured human cells by Mycoplasma penetrans.

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14 October 2018

Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation

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14 October 2018

Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus

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14 October 2018

Cellular cholesterol efflux mediated by cyclodextrins

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Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin

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14 October 2018

Caveolin, a protein component of caveolae membrane coats

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14 October 2018

Lipoprotein is a predominant Toll-like receptor 2 ligand in Staphylococcus aureus cell wall components.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A microbial TLR2 agonist imparts macrophage-activating ability to apolipoprotein A-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20113368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2567.2009.03232.X

1 reference

Europe PubMed Central

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17 January 2020

0 references

1 reference

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17 January 2020

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