Genotoxic stress causes the accumulation of the splicing regulator Sam68 in nuclear foci of transcriptionally active chromatin. (Q39746746)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20110258%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Genotoxic stress causes the accumulation of the splicing regulator Sam68 in nuclear foci of transcriptionally active chromatin (English)

1 reference

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17 January 2020

1 reference

2

1 reference

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17 January 2020

Claudio Sette

series ordinal

3

1 reference

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17 January 2020

author name string

Roberta Busà

series ordinal

1

1 reference

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17 January 2020

language of work or name

English

0 references

publication date

27 January 2010

1 reference

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17 January 2020

published in

Nucleic Acids Research

1 reference

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17 January 2020

volume

38

1 reference

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17 January 2020

issue

9

1 reference

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17 January 2020

page(s)

3005-3018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20110258%20AND%20SRC:MED&resulttype=core&format=json

Sam68 relocalization into stress granules in response to oxidative stress through complexing with TIA-1

17 January 2020

cites work

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Alternative splicing and tumor progression

14 September 2017

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Sam68 regulates translation of target mRNAs in male germ cells, necessary for mouse spermatogenesis

14 September 2017

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Phase I study of ixabepilone, mitoxantrone, and prednisone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel-based therapy: a study of the department of defense prostate cancer clinical trials consort

14 September 2017

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Cellular stress and RNA splicing

14 September 2017

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Suppression of HIV-1 Nef translation by Sam68 mutant-induced stress granules and nef mRNA sequestration

14 September 2017

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Splicing and splice factor SRp55 participate in the response to DNA damage by changing isoform ratios of target genes

14 September 2017

1 reference

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Transcription of Satellite III non-coding RNAs is a general stress response in human cells

14 September 2017

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Subcellular distribution of human RDM1 protein isoforms and their nucleolar accumulation in response to heat shock and proteotoxic stress

14 September 2017

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The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x

14 September 2017

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The RNA-binding protein Sam68 contributes to proliferation and survival of human prostate cancer cells

14 September 2017

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Phosphorylation and functions of the RNA polymerase II CTD

14 September 2017

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Promyelocytic leukemia nuclear bodies behave as DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1 and the kinases ATM, Chk2, and ATR.

14 September 2017

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hnRNP A1 relocalization to the stress granules reflects a role in the stress response.

14 September 2017

1 reference

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The connection between splicing and cancer.

14 September 2017

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Unbalanced alternative splicing and its significance in cancer

14 September 2017

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Cyclin D1b variant influences prostate cancer growth through aberrant androgen receptor regulation

14 September 2017

1 reference

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Regulation of CD44 alternative splicing by SRm160 and its potential role in tumor cell invasion

14 September 2017

1 reference

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The human SWI/SNF subunit Brm is a regulator of alternative splicing

14 September 2017

1 reference

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Understanding alternative splicing: towards a cellular code

14 September 2017

1 reference

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BRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II.

14 September 2017

1 reference

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Structural and functional characterization of noncoding repetitive RNAs transcribed in stressed human cells

14 September 2017

1 reference

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Splicing DNA-damage responses to tumour cell death.

14 September 2017

1 reference

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ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions

14 September 2017

1 reference

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Tr-kit promotes the formation of a multimolecular complex composed by Fyn, PLCgamma1 and Sam68.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014

Sam68, the KH domain-containing superSTAR.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014

Mechanisms of alternative pre-messenger RNA splicing

14 September 2017

1 reference

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14 September 2017

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CD44: from adhesion molecules to signalling regulators

14 September 2017

1 reference

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Sam68 enhances the cytoplasmic utilization of intron-containing RNA and is functionally regulated by the nuclear kinase Sik/BRK.

14 September 2017

1 reference

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Signal-dependent regulation of splicing via phosphorylation of Sam68

14 September 2017

1 reference

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Stress granules: sites of mRNA triage that regulate mRNA stability and translatability

14 September 2017

1 reference

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Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.

14 September 2017

1 reference

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Stress-induced nuclear bodies are sites of accumulation of pre-mRNA processing factors

14 September 2017

1 reference

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Regulation of alternative pre-mRNA splicing by the ERK MAP-kinase pathway

14 September 2017

1 reference

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Glycogen synthase kinase 3beta and extracellular signal-regulated kinase inactivate heat shock transcription factor 1 by facilitating the disappearance of transcriptionally active granules after heat shock

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014

DNA damage regulates alternative splicing through inhibition of RNA polymerase II elongation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014

Cancer-associated regulation of alternative splicing

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014

Cyclin D1b is aberrantly regulated in response to therapeutic challenge and promotes resistance to estrogen antagonists

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014

The early response to DNA damage can lead to activation of alternative splicing activity resulting in CD44 splice pattern changes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014

Genotoxic stress induces coordinately regulated alternative splicing of the p53 modulators MDM2 and MDM4.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014

Topoisomerase I and II inhibitors control caspase-2 pre-messenger RNA splicing in human cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014

Transcriptional activation of a constitutive heterochromatic domain of the human genome in response to heat shock.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014

Dynamic relocation of transcription and splicing factors dependent upon transcriptional activity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014

CD44: structure, function, and association with the malignant process.

25 September 2017

2 references

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25 September 2017

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ004

The nuclear RNA-binding protein Sam68 translocates to the cytoplasm and associates with the polysomes in mouse spermatocytes

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875014

Stress-induced transcription of satellite III repeats.

15 June 2018

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Differentiation-dependent chromatin alterations precede and accompany transcription of immunoglobulin light chain genes

15 June 2018

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A method for mapping the distributions of modified and variant histones among mono- and polynucleosomes

15 June 2018

1 reference

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Nuclear stress bodies: a heterochromatin affair?

15 June 2018

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STAT3 is enriched in nuclear bodies

20 August 2018

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DNA damage induced by DNA topoisomerase I- and topoisomerase II-inhibitors detected by histone H2AX phosphorylation in relation to the cell cycle phase and apoptosis

20 August 2018

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c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for mitoxantrone- and anisomycin-induced apoptosis in HL-60 cells

20 August 2018

1 reference

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Prognostic significance of CD44v5 expression in human thymic epithelial neoplasms

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20110258

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKQ004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20110258%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20110258%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

20110258

1 reference