Mice lacking the norepinephrine transporter are supersensitive to psychostimulants (Q39749651)

14 September 2017

Mice lacking the norepinephrine transporter are supersensitive to psychostimulants (English)

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Solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2

14 September 2017

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GOA release 2020-03-11

author

Raul Gainetdinov

2

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8

Caron MG

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Xu F

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Wetsel WC

3

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Jones SR

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Bohn LM

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Miller GW

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Wang YM

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14 September 2017

language of work or name

English

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publication date

1 May 2000

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3

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5

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465-471

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https://scigraph.springernature.com/pub.10.1038/74839

14 September 2017

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Loss of autoreceptor functions in mice lacking the dopamine transporter.

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Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine.

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The automated Tail Suspension Test: a computerized device which differentiates psychotropic drugs.

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Behavioural evidence for supersensitivity of postsynaptic dopamine receptors in the mesolimbic system after chronic administration of desipramine

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Molecular and cellular basis of addiction

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Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

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Cocaine self-administration in dopamine-transporter knockout mice

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Cocaine reward models: conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice

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Alpha2-adrenergic control of dopamine overflow and metabolism in mouse striatum.

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Clonidine modulates dopamine cell firing in rat ventral tegmental area

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Heterogeneity of electrically evoked dopamine release and reuptake in substantia nigra, ventral tegmental area, and striatum

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[3H]desipramine binding to rat brain tissue: binding to both noradrenaline uptake sites and sites not related to noradrenaline neurons

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Spontaneous and amphetamine-evoked release of cerebellar noradrenaline after sensorimotor cortex contusion: an in vivo microdialysis study in the awake rat.

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Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity

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Conditioned place preference and locomotor activation produced by injection of psychostimulants into ventral pallidum.

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Pharmacological characterization of dopamine-stimulated [35S]-guanosine 5'(gamma-thiotriphosphate) ([35S]GTPgammaS) binding in rat striatal membranes.

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7 January 2021

Identifiers

DOI

10.1038/74839

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14 September 2017

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