Involvement of a subpopulation of neuronal M4 muscarinic acetylcholine receptors in the antipsychotic-like effects of the M1/M4 preferring muscarinic receptor agonist xanomeline. (Q39758681)

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English	Involvement of a subpopulation of neuronal M4 muscarinic acetylcholine receptors in the antipsychotic-like effects of the M1/M4 preferring muscarinic receptor agonist xanomeline.	scientific article

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29 January 2020

Involvement of a subpopulation of neuronal M4 muscarinic acetylcholine receptors in the antipsychotic-like effects of the M1/M4 preferring muscarinic receptor agonist xanomeline (English)

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29 January 2020

Gitta Wörtwein

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29 January 2020

Morgane Thomsen

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29 January 2020

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29 January 2020

Anders Fink-Jensen

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29 January 2020

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Pia Weikop

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29 January 2020

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Ditte Dencker

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29 January 2020

Jongrye Jeon

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29 January 2020

Thomas N Sager

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29 January 2020

Arne Mørk

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29 January 2020

Jürgen Wess

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29 January 2020

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1 April 2011

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29 January 2020

Journal of Neuroscience

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29 January 2020

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29 January 2020

16

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29 January 2020

5905-5908

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29 January 2020

Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xanomeline, an M(1)/M(4) preferring muscarinic cholinergic receptor agonist, produces antipsychotic-like activity in rats and mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elucidating the role of muscarinic receptors in psychosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The muscarinic receptor agonist xanomeline has an antipsychotic-like profile in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscarinic M4 receptor inhibition of dopamine D1-like receptor signalling in rat nucleus accumbens

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscarinic receptors as a target for drugs treating schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

M4 muscarinic receptors regulate the dynamics of cholinergic and dopaminergic neurotransmission: relevance to the pathophysiology and treatment of related CNS pathologies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotypical characterization of the rat striatal neurons expressing muscarinic receptor genes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacologic interactions between the muscarinic cholinergic and dopaminergic systems in the modulation of prepulse inhibition in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in kinetics of xanomeline binding and selectivity of activation of G proteins at M(1) and M(2) muscarinic acetylcholine receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective muscarinic receptor agonist xanomeline as a novel treatment approach for schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immediate and delayed consequences of xanomeline wash-resistant binding at the M3 muscarinic receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of amphetamine-induced activity by the non-selective muscarinic receptor agonist, xanomeline, is absent in muscarinic M4 receptor knockout mice and attenuated in muscarinic M1 receptor knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of prepulse inhibition through both M(1) and M (4) muscarinic receptors in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A subpopulation of neuronal M4 muscarinic acetylcholine receptors plays a critical role in modulating dopamine-dependent behaviors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antipsychotic-induced catalepsy is attenuated in mice lacking the M4 muscarinic acetylcholine receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of muscarinic acetylcholine and dopamine receptor mRNAs in rat basal ganglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Climbing behavior induced by apomorphine in mice: a simple test for the study of dopamine receptors in striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunological localization of m1-m5 muscarinic acetylcholine receptors in peripheral tissues and brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21508215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0370-11.2011

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29 January 2020

PMC publication ID

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29 January 2020

PubMed publication ID

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29 January 2020

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