Targeting PKC-β II and PKB Connection: Design of Dual Inhibitors (Q39760304)

14 September 2017

Targeting PKC-β II and PKB Connection: Design of Dual Inhibitors (English)

1 reference

14 September 2017

Kapil Jain

1

1 reference

PubMed ID

27466950

14 September 2017

Dara Ajay

series ordinal

2

1 reference

PubMed ID

27466950

14 September 2017

M Elizabeth Sobhia

series ordinal

3

1 reference

14 September 2017

31 March 2011

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14 September 2017

Molecular Informatics

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14 September 2017

30

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14 September 2017

4

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14 September 2017

329-344

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Regulation of protein kinase C.

14 September 2017

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions

21 January 2018

1 reference

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Protein kinase C inhibitors as novel anticancer drugs

21 January 2018

1 reference

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The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Enzastaurin, a protein kinase Cbeta- selective inhibitor, and its potential application as an anticancer agent in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Protein kinase C betaII regulates Akt phosphorylation on Ser-473 in a cell type- and stimulus-specific fashion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Regulation of protein kinase B/Akt activity and Ser473 phosphorylation by protein kinase Calpha in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Protein kinase C intervention: the state of play

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Acyclic N-(azacycloalkyl)bisindolylmaleimides: isozyme selective inhibitors of PKCβ

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Convergence of multiple signaling cascades at glycogen synthase kinase 3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Iterative partial equalization of orbital electronegativity—a rapid access to atomic charges

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Structure of the catalytic domain of human protein kinase C beta II complexed with a bisindolylmaleimide inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Synthesis and structure based optimization of novel Akt inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Identification of inhibitors of protein kinase B using fragment-based lead discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Discovery of trans-3,4'-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation

21 January 2018

1 reference

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Characterization of a protein kinase B inhibitor in vitro and in insulin-treated liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Synthesis of anilino-monoindolylmaleimides as potent and selective PKCbeta inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Novel indolylindazolylmaleimides as inhibitors of protein kinase C-beta: synthesis, biological activity, and cardiovascular safety.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

(S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: isozyme selective inhibitors of protein kinase C beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Drug-like properties and the causes of poor solubility and poor permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Lead- and drug-like compounds: the rule-of-five revolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

International Commission for Protection Against Environmental Mutagens and Carcinogens. Use of SAR in computer-assisted prediction of carcinogenicity and mutagenicity of chemicals by the TOPKAT program

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Restart procedures for the conjugate gradient method

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201000082

Disposition of LY333531, a selective protein kinase C beta inhibitor, in the Fischer 344 rat and beagle dog

21 January 2018

1 reference

COCI

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.201000082

8 April 2023

Identifiers

DOI

10.1002/MINF.201000082

1 reference

14 September 2017

1 reference

PubMed ID

27466950