HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer (Q39763266)

14 September 2017

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer (English)

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14 September 2017

5

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14 September 2017

Charles J David

1

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14 September 2017

Mo Chen

series ordinal

2

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14 September 2017

Marcela Assanah

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3

1 reference

14 September 2017

Peter Canoll

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4

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14 September 2017

language of work or name

English

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publication date

13 December 2009

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14 September 2017

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14 September 2017

463

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14 September 2017

364-368

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14 September 2017

7279

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https://scigraph.springernature.com/pub.10.1038/nature08697

14 September 2017

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cites work

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Crystal structure of human spliceosomal U1 snRNP at 5.5 Å resolution

22 September 2017

1 reference

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p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

22 September 2017

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22 September 2017

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Integration of external signaling pathways with the core transcriptional network in embryonic stem cells

22 September 2017

1 reference

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950088

Pyruvate kinase M2 is a phosphotyrosine-binding protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950088

Crossregulation and functional redundancy between the splicing regulator PTB and its paralogs nPTB and ROD1

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950088

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

22 September 2017

1 reference

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Knockdown of polypyrimidine tract-binding protein suppresses ovarian tumor cell growth and invasiveness in vitro

22 September 2017

1 reference

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MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950088

The polypyrimidine tract binding protein (PTB) represses splicing of exon 6B from the beta-tropomyosin pre-mRNA by directly interfering with the binding of the U2AF65 subunit

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950088

RB and cell cycle progression

22 September 2017

1 reference

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Intronic binding sites for hnRNP A/B and hnRNP F/H proteins stimulate pre-mRNA splicing

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950088

Dissection of transcriptional programmes in response to serum and c-Myc in a human B-cell line.

22 September 2017

1 reference

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On the Origin of Cancer Cells

22 September 2017

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c-MYC activates protein kinase A (PKA) by direct transcriptional activation of the PKA catalytic subunit beta (PKA-Cbeta) gene

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950088

Quantitative proteomic analysis of Myc oncoprotein function

22 September 2017

1 reference

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Differential expression of the early lung cancer detection marker, heterogeneous nuclear ribonucleoprotein-A2/B1 (hnRNP-A2/B1) in normal breast and neoplastic breast cancer.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950088

hnRNP A1 recruited to an exon in vivo can function as an exon splicing silencer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950088

Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors.

22 September 2017

1 reference

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Human hnRNP protein A1 gene expression. Structural and functional characterization of the promoter.

22 September 2017

1 reference

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RNA binding specificity of hnRNP A1: significance of hnRNP A1 high-affinity binding sites in pre-mRNA splicing

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950088

Alternative splicing of the pyruvate kinase M gene in a minigene system

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950088

Aerobic glycolysis during lymphocyte proliferation

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950088

Novel modes of splicing repression by PTB.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950088

Relative amounts of antagonistic splicing factors, hnRNP A1 and ASF/SF2, change during neoplastic lung growth: implications for pre-mRNA processing

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950088

Fibroblast growth factor receptor-1 alpha-exon exclusion and polypyrimidine tract-binding protein in glioblastoma multiforme tumors.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950088

hnRNP A1 functions with specificity in repression of SMN2 exon 7 splicing

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20010808

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Normal and mutant human β-globin pre-mRNAs are faithfully and efficiently spliced in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20010808

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Temporally distinctive changes of alternative splicing patterns during myogenic differentiation of C2C12 cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20010808

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE08697

1 reference

Dimensions Publication ID

14 September 2017

0 references

1 reference

14 September 2017

1 reference