The insulin receptor concept and its relation to the treatment of diabetes (Q39764436)

14 September 2017

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title

The insulin receptor concept and its relation to the treatment of diabetes (English)

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14 September 2017

G M Ward

1

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14 September 2017

1 February 1987

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14 September 2017

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14 September 2017

33

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14 September 2017

2

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14 September 2017

156-170

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https://scigraph.springernature.com/pub.10.2165/00003495-198733020-00004

14 September 2017

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cites work

Downregulation of Insulin Receptors in Obese Man

1 reference

12 December 2020

The effect of insulin treatment on insulin secretion and insulin action in type II diabetes mellitus.

1 reference

12 December 2020

Characterization of insulin receptors in patients with the syndromes of insulin resistance and acanthosis nigricans

1 reference

12 December 2020

Gliclazide therapy is associated with potentiation of postbinding insulin action in obese, non-insulin-dependent diabetic subjects.

1 reference

12 December 2020

Insulin receptor: evidence that it is a protein kinase

1 reference

12 December 2020

Concomitant insulin and sulfonylurea therapy in patients with type II diabetes. Effects on glucoregulation and lipid metabolism.

1 reference

12 December 2020

Purification of insulin receptor with full binding activity

1 reference

12 December 2020

Insulin receptor: structure and function

1 reference

12 December 2020

Diurnal variation in oral glucose tolerance: blood sugar and plasma insulin levels morning, afternoon, and evening.

1 reference

12 December 2020

Insulin-dependent regulation of insulin receptor concentrations: a direct demonstration in cell culture.

1 reference

12 December 2020

C-peptide in juvenile diabetics beyond the postinitial remission period. Relation to clinical manifestations at onset of diabetes, remission and diabetic control

1 reference

12 December 2020

Validation of a practical in vivo insulin dose-response curve in man.

1 reference

12 December 2020

Investigation of Insulin Sensitivity in Treated Subjects with Ketosis-prone Diabetes Mellitus

1 reference

12 December 2020

Insulin-receptor interaction in the obese-hyperglycemic mouse. A model of insulin resistance

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12 December 2020

Effect of a High Carbohydrate Diet on Insulin Binding to Adipocytes and on Insulin Action in vivo in Man

1 reference

12 December 2020

Role of insulin receptors in insulin-resistant states

1 reference

12 December 2020

Metformin reduces insulin requirement in Type 1 (insulin-dependent) diabetes

1 reference

12 December 2020

Improved in vivo insulin effect during continuous subcutaneous insulin infusion in patients with IDDM.

1 reference

12 December 2020

Sulfonylureas in insulin-dependent (type I) diabetes: evidence for an extrapancreatic effect in vivo

1 reference

12 December 2020

Selective potentiation of insulin-mediated glucose disposal in normal dogs by the sulfonylurea glipizide

1 reference

12 December 2020

Heterogeneity of insulin receptors in patients with untreated insulin-dependent diabetes mellitus

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12 December 2020

Sulfonylurea potentiates insulin-induced recruitment of glucose transport carrier in rat adipocytes

1 reference

12 December 2020

Acanthosis nigricans, hirsutism, insulin resistance and insulin receptor defect

1 reference

12 December 2020

Cooperativity in ligand binding: a new graphic analysis

1 reference

12 December 2020

Autoantibodies to the insulin receptor: clinical significance and experimental applications

1 reference

12 December 2020

Effects of sulfonylurea therapy on insulin binding to mononuclear leukocytes of diabetic patients

1 reference

12 December 2020

Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus

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12 December 2020

Quantitative aspects of the insulin-receptor interaction in liver plasma membranes.

1 reference

12 December 2020

Fluctuations in the affinity and concentration of insulin receptors on circulating monocytes of obese patients: effects of starvation, refeeding, and dieting

1 reference

12 December 2020

Effect of insulin on human erythrocyte membrane fluidity in diabetes mellitus

1 reference

12 December 2020

Type II diabetes and insulin resistance. Evidence of lack of inherent cellular defects in insulin sensitivity

1 reference

12 December 2020

The effect of a high-fat diet on glucose, insulin sensitivity and plasma insulin in rats

1 reference

12 December 2020

The effect of sulfhydryl active agents on insulin binding to the erythrocyte insulin receptor

1 reference

12 December 2020

Potentiation of Insulin Action by a Sulfonylurea in Primary Cultures of Hepatocytes from Normal and Diabetic Rats

1 reference

12 December 2020

Abnormal dietary regulation of erythrocyte insulin receptor affinity in non-insulin-dependent diabetes mellitus

1 reference

12 December 2020

Diurnal variation in insulin sensitivity.

1 reference

12 December 2020

The subunit structure of the high affinity insulin receptor. Evidence for a disulfide-linked receptor complex in fat cell and liver plasma membranes

1 reference

12 December 2020

Mathematics of hormone-receptor interaction. I. Basic principles.

1 reference

12 December 2020

Effect of the Membrane Lipid Environment on the Properties of Insulin Receptors

1 reference

12 December 2020

Insulin-independent diabetes mellitus: metabolic characteristics

1 reference

12 December 2020

Circadian profiles of insulin receptors in insulin-dependent diabetics in usual and poor metabolic control

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12 December 2020

Effect of sulphonylurea on insulin secretion and glucose control in insulin-treated diabetics

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12 December 2020

Increased insulin receptors after exercise in patients with insulin-dependent diabetes mellitus.

1 reference

12 December 2020

Sulphonylureas in vitro do not alter insulin binding or insulin effect on amino acid transport in rat hepatocytes

1 reference

12 December 2020

Receptors, Antireceptor Antibodies and Mechanisms of Insulin Resistance

1 reference

12 December 2020

Decreased insulin binding to adipocytes and circulating monocytes from obese subjects

1 reference

12 December 2020

Extrapancreatic action of sulphonylureas: effect of gliquidone on insulin and glucagon binding to rat liver plasma membranes

1 reference

12 December 2020

Insulin binding and insulin response of adipocytes from rats adapted to fat feeding

1 reference

12 December 2020

Insulin receptor binding increased by high carbohydrate low fat diet in non-insulin-dependent diabetics

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12 December 2020

Change in affinity of insulin receptors following oral glucose in normal adults

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12 December 2020

Depletion and disruption of dietary fibre. Effects on satiety, plasma-glucose, and serum-insulin

1 reference

12 December 2020

Cell membrane as a primary site of insulin action

1 reference

12 December 2020

Insulin resistance, acanthosis nigricans, and polycystic ovaries associated with a circulating inhibitor of postbinding insulin action.

1 reference

12 December 2020

Carbohydrate intake affects insulin binding to human erythrocytes in normal weight subjects but not in subjects with family obesity

1 reference

12 December 2020

Disulfide exchange between insulin and its receptor. A possible post-binding step in insulin action

1 reference

12 December 2020

Monoiodoinsulin: Demonstration of its biological activity and binding to fat cells and liver membranes

1 reference

12 December 2020

Comparison of plasma insulin levels following administration of tolbutamide and glucose

1 reference

12 December 2020

Diurnal Variation in Insulin Binding to Human Monocytes*

1 reference

12 December 2020

Metformin and insulin receptors

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12 December 2020

Sulphonylureas increase the number of insulin receptors

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12 December 2020

Transient effect of the combination of insulin and sulfonylurea (glibenclamide) on glycemic control in non-insulin dependent diabetics poorly controlled with insulin alone.

1 reference

12 December 2020

Subunit structure of the insulin receptor of the human lymphocyte

1 reference

12 December 2020

Insulin Receptors in the Heart Muscle: Demonstration of Specific Binding Sites and Impairment of Insulin Binding in the Plasma Membrane of the Obese Hyperglycemic Mouse

1 reference

12 December 2020

Short-term regulation of insulin receptor affinity in man

1 reference

12 December 2020

Impaired insulin action in newly diagnosed type 1 (insulin-dependent) diabetes mellitus

1 reference

12 December 2020

An anomalous postprandial increase in erythrocyte insulin receptor affinity associated with hyperinsulinemia.

1 reference

12 December 2020

Influence of metformin on metabolic effect of insulin in human adipose tissue in vitro

1 reference

12 December 2020

Differences in organizational structure of insulin receptor on rat adipocyte and liver plasma membranes: role of disulfide bonds

1 reference

12 December 2020

Insulin Resistance, Acanthosis Nigricans, and Normal Insulin Receptors in a Young Woman: Evidence for a Postreceptor Defect

1 reference

12 December 2020

Regulation of insulin receptors in normal and abnormal physiology in humans

1 reference

12 December 2020

The effect of food intake on insulin receptor in man

1 reference

12 December 2020

Increased insulin sensitivity and cellular insulin binding in obese diabetics following treatment with glibenclamide

1 reference

12 December 2020

Insulin sensitivity in newly diagnosed type 1 diabetics after ketoacidosis and after three months of insulin therapy

1 reference

12 December 2020

Insulin Therapy in Obese, Non-insulin-dependent Diabetes Induces Improvements in Insulin Action and Secretion that Are Maintained for Two Weeks After Insulin Withdrawal

1 reference

12 December 2020

Preferential degradation of the beta subunit of purified insulin receptor. Effect on insulin binding and protein kinase activities of the receptor

1 reference

12 December 2020

Pulsatile Insulin Has Greater Hypoglycemic Effect Than Continuous Delivery

1 reference

12 December 2020

Defect in insulin receptor phosphorylation in erythrocytes and fibroblasts associated with severe insulin resistance

1 reference

12 December 2020

A postbinding inhibitor of insulin action. Increased concentrations in the plasma of non-insulin-dependent diabetic subjects.

1 reference

12 December 2020

Improved diabetic control in insulin-dependent diabetics treated with insulin and glibenclamide

1 reference

12 December 2020

Radioimmunoassay of the Insulin Receptor: A New Probe of Receptor Structure and Function

1 reference

12 December 2020

Monoiodoinsulin. Preparation, purification, and characterization of a biologically active derivative substituted predominantly on tyrosine A14.

1 reference

12 December 2020

Effects of tolbutamide on insulin binding to isolated fat cells of the rat

1 reference

12 December 2020

Defect in insulin binding to receptors in obese man. Amelioration with calorie restriction

1 reference

12 December 2020

The syndromes of insulin resistance and acanthosis nigricans. Insulin-receptor disorders in man.

1 reference

12 December 2020

Sulfonylurea treatment of insulin-independent diabetes mellitus

1 reference

12 December 2020

The insulin receptor: its role in insulin resistance of obesity and diabetes

1 reference

12 December 2020

Unabsorbable carbohydrates and diabetes: Decreased post-prandial hyperglycaemia

1 reference

12 December 2020

Insulin binding in diabetes. Relationships with plasma insulin levels and insulin sensitivity

1 reference

12 December 2020

Insulin activates a tyrosine-specific protein kinase in extracts of 3T3-L1 adipocytes and human placenta.

1 reference

12 December 2020

Improved glucose control in maturity-onset diabetes treated with high-carbohydrate-modified fat diet

1 reference

12 December 2020

Increased insulin binding to adipocytes and monocytes and increased insulin sensitivity of glucose transport and metabolism in adipocytes from non-insulin-dependent diabetics after a low-fat/high-starch/high-fiber diet.

1 reference

12 December 2020

Photoaffinity labeling of insulin receptor of rat adiopocyte plasma membrane

1 reference

12 December 2020

The Alström syndrome. Report of three cases with further delineation of the clinical, pathophysiological, and genetic aspects of the disorder

1 reference

12 December 2020

Pulsatile, synchronous basal insulin and glucagon secretion in man

1 reference

12 December 2020

1 reference

12 December 2020

In vitro effects of a sulfonylurea on insulin action in adipocytes. Potentiation of insulin-stimulated hexose transport

1 reference

12 December 2020

A high carbohydrate leguminous fibre diet improves all aspects of diabetic control

1 reference

12 December 2020

Antibodies That Impair Insulin Receptor Binding in an Unusual Diabetic Syndrome with Severe Insulin Resistance

1 reference

12 December 2020

Absence of covalent binding by insulin to erythrocyte and reticulocyte insulin receptors

1 reference

12 December 2020

Effect of carbohydrate restriction and high carbohydrates diets on men with chemical diabetes

1 reference

12 December 2020

A comparison of insulin binding by liver plasma membranes of rats fed a high glucose diet or a high fat diet

1 reference

12 December 2020

Improved Glucose Tolerance with High Carbohydrate Feeding in Mild Diabetes

1 reference

12 December 2020

Some Endocrine and Metabolic Aspects of Obesity

1 reference

12 December 2020

Direct in vitro effect of a sulfonylurea to increase human fibroblast insulin receptors

1 reference

12 December 2020

Metformin reduces post-prandial insulin needs in type I (insulin-dependent) diabetic patients: Assessment by the artificial pancreas

1 reference

12 December 2020

Biguanide treatment increases the number of insulin-receptor sites on human erythrocytes

1 reference

12 December 2020

Insulin stimulation of phosphorylation of the beta subunit of the insulin receptor. Formation of both phosphoserine and phosphotyrosine

1 reference

12 December 2020

Effects of diet on the cellular insulin binding and the insulin sensitivity in young healthy subjects

1 reference

12 December 2020

Insulin binding leads to the formation of covalent (-S-S-) hormone receptor complexes

1 reference

12 December 2020

Sulfonylureas do not affect insulin binding or glycemic control in insulin-dependent diabetics

1 reference

12 December 2020

Fibre, diabetes, and hyperlipidaemia

1 reference

12 December 2020

Cell culture studies on patients with extreme insulin resistance. I. Receptor defects on cultured fibroblasts.

1 reference

12 December 2020

Effects of dietary changes on cellular insulin binding and in vivo insulin sensitivity

1 reference

12 December 2020

The Effects of Acute and Chronic Starvation on Insulin Binding to Isolated Human Adipocytes*

1 reference

12 December 2020

Tolbutamide does not alter insulin requirement in Type 1 (insulin-dependent) diabetes

1 reference

12 December 2020

10.2165/00003495-198733020-00004

Identifiers

DOI

1 reference

PubMed ID

3552593

Dimensions Publication ID

14 September 2017

1006150743

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Fatcat ID

release_v62ueeyk7rht5oxb4zmgu2xnem

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Fatcat

https://api.fatcat.wiki/v0/release/v62ueeyk7rht5oxb4zmgu2xnem

24 November 2022

mapped directly with Wikidata item

PubMed ID

3552593

1 reference

PubMed ID

3552593