AnnexinA5 renders dead tumor cells immunogenic--implications for multimodal cancer therapies. (Q39775727)

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12 February 2020

title

AnnexinA5 renders dead tumor cells immunogenic--implications for multimodal cancer therapies (English)

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12 February 2020

1

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12 February 2020

Luis E Munoz

5

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12 February 2020

Martin Herrmann

6

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author name string

Petra Schildkopf

2

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12 February 2020

Franz Rödel

3

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12 February 2020

Eva-Maria Weiss

4

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Udo S Gaipl

8

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12 February 2020

Rainer Fietkau

7

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12 February 2020

publication date

1 December 2009

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Journal of Immunotoxicology

12 February 2020

published in

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volume

6

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issue

4

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page(s)

209-216

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Is interleukin-1 a good or bad 'guy' in tumor immunobiology and immunotherapy?

12 February 2020

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Chromatin and cell death

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Requirement of dying cells and environmental adjuvants for the induction of autoimmunity

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Inhibition of phosphatidylserine recognition heightens the immunogenicity of irradiated lymphoma cells in vivo

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Involvement of phosphatidylserine, alphavbeta3, CD14, CD36, and complement C1q in the phagocytosis of primary necrotic lymphocytes by macrophages

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Annexin A5 is not essential for skeletal development

21 January 2018

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Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

21 January 2018

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The immune reaction against allogeneic necrotic cells is reduced in Annexin A5 knock out mice whose macrophages display an anti-inflammatory phenotype.

21 January 2018

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Modulation of the immune system by dying cells and the phosphatidylserine-ligand annexin A5.

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Immunogenic and tolerogenic cell death

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Characterization of cDNA encoding human placental anticoagulant protein (PP4): homology with the lipocortin family

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Extracellular ATP induces oscillations of intracellular Ca2+ and membrane potential and promotes transcription of IL-6 in macrophages.

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Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus

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How dying cells alert the immune system to danger

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Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

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From regulation of dying cell engulfment to development of anti-cancer therapy

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Clearance of apoptotic cells: getting rid of the corpses.

21 January 2018

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Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells

21 January 2018

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Hyperthermia in combination with X-irradiation induces inflammatory forms of cell death

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Molecular identification of a danger signal that alerts the immune system to dying cells

21 January 2018

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Low-dose chemotherapeutic agents regulate small Rho GTPase activity in dendritic cells

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Recognition of live phosphatidylserine-labeled tumor cells by dendritic cells: a novel approach to immunotherapy of skin cancer

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Immunogenic cancer cell death: a key-lock paradigm

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Melanoma-specific memory T cells are functionally active in Ret transgenic mice without macroscopic tumors

21 January 2018

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A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

21 January 2018

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The anticancer immune response: indispensable for therapeutic success?

21 January 2018

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Calreticulin exposure is required for the immunogenicity of γ-irradiation and UVC light-induced apoptosis

21 January 2018

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Immunosuppressive effects of apoptotic cells

21 January 2018

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10.3109/15476910903204058

21 January 2018

Identifiers

DOI

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12 February 2020

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