Analysis of the viral elements required in the nuclear import of HIV-1 DNA. (Q39778927)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19889772%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Analysis of the viral elements required in the nuclear import of HIV-1 DNA (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19889772%20AND%20SRC:MED&resulttype=core&format=json

nucleic acid sequence analysis

11 February 2020

main subject

HIV

0 references

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19889772%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

author name string

Lise Rivière

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19889772%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Jean-Luc Darlix

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19889772%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

language of work or name

English

0 references

publication date

4 November 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19889772%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19889772%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

84

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19889772%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19889772%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

page(s)

729-739

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19889772%20AND%20SRC:MED&resulttype=core&format=json

HIV-1 exploits importin 7 to maximize nuclear import of its DNA genome

11 February 2020

cites work

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VSV-G pseudotyping rescues HIV-1 CA mutations that impair core assembly or stability.

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22 September 2017

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Localization of HIV-1 Vpr to the nuclear envelope: impact on Vpr functions and virus replication in macrophages

22 September 2017

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Evidence for direct involvement of the capsid protein in HIV infection of nondividing cells

22 September 2017

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Human immunodeficiency virus bearing a disrupted central DNA flap is pathogenic in vivo

22 September 2017

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22 September 2017

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22 September 2017

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tRNAs promote nuclear import of HIV-1 intracellular reverse transcription complexes

22 September 2017

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Nuclear import defect of human immunodeficiency virus type 1 DNA flap mutants is not dependent on the viral strain or target cell type

22 September 2017

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The effect of capsid mutations on HIV-1 uncoating

22 September 2017

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The central DNA flap of the human immunodeficiency virus type 1 is important for viral replication

22 September 2017

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Wild-type and central DNA flap defective HIV-1 lentiviral vector genomes: intracellular visualization at ultrastructural resolution levels

22 September 2017

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HIV-1 integrase is capable of targeting DNA to the nucleus via an importin alpha/beta-dependent mechanism.

22 September 2017

1 reference

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Evidence for a functional link between uncoating of the human immunodeficiency virus type 1 core and nuclear import of the viral preintegration complex

22 September 2017

1 reference

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The cell cycle independence of HIV infections is not determined by known karyophilic viral elements

22 September 2017

1 reference

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Contribution of the C-terminal tri-lysine regions of human immunodeficiency virus type 1 integrase for efficient reverse transcription and viral DNA nuclear import

22 September 2017

1 reference

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Gene therapy progress and prospects: viral trafficking during infection

22 September 2017

1 reference

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Green fluorescent protein-tagged adeno-associated virus particles allow the study of cytosolic and nuclear trafficking

22 September 2017

1 reference

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Importin 7 may be dispensable for human immunodeficiency virus type 1 and simian immunodeficiency virus infection of primary macrophages

22 September 2017

1 reference

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Human immunodeficiency virus type 1 KK26-27 matrix mutants display impaired infectivity, circularization and integration but not nuclear import

22 September 2017

1 reference

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Class II integrase mutants with changes in putative nuclear localization signals are primarily blocked at a postnuclear entry step of human immunodeficiency virus type 1 replication

22 September 2017

1 reference

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Evaluation of the functional involvement of human immunodeficiency virus type 1 integrase in nuclear import of viral cDNA during acute infection

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

Role of Nup98 in nuclear entry of human immunodeficiency virus type 1 cDNA.

22 September 2017

1 reference

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Capsid is a dominant determinant of retrovirus infectivity in nondividing cells

22 September 2017

1 reference

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Requirement for integrase during reverse transcription of human immunodeficiency virus type 1 and the effect of cysteine mutations of integrase on its interactions with reverse transcriptase.

22 September 2017

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Assessment of the role of the central DNA flap in human immunodeficiency virus type 1 replication by using a single-cycle replication system

22 September 2017

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Human immunodeficiency virus type 1 DNA nuclear import and integration are mitosis independent in cycling cells

22 September 2017

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Nuclear import of HIV-1 intracellular reverse transcription complexes is mediated by importin 7

22 September 2017

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22 September 2017

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Functional Surfaces of the Human Immunodeficiency Virus Type 1 Capsid Protein

22 September 2017

1 reference

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Impact of the central polypurine tract on the kinetics of human immunodeficiency virus type 1 vector transduction

22 September 2017

1 reference

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Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import

22 September 2017

1 reference

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Wild-type levels of nuclear localization and human immunodeficiency virus type 1 replication in the absence of the central DNA flap

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

Nuclear localization of human immunodeficiency virus type 1 preintegration complexes (PICs): V165A and R166A are pleiotropic integrase mutants primarily defective for integration, not PIC nuclear import

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

Characterization of intracellular reverse transcription complexes of human immunodeficiency virus type 1.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

Nucleocytoplasmic shuttling by human immunodeficiency virus type 1 Vpr.

22 September 2017

1 reference

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Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

Two putative alpha-helical domains of human immunodeficiency virus type 1 Vpr mediate nuclear localization by at least two mechanisms

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

The karyophilic properties of human immunodeficiency virus type 1 integrase are not required for nuclear import of proviral DNA.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

Identification of critical amino acid residues in human immunodeficiency virus type 1 IN required for efficient proviral DNA formation at steps prior to integration in dividing and nondividing cells.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

Nuclear import of human immunodeficiency virus type-1 preintegration complexes.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

Characterization of HIV-1 vpr nuclear import: analysis of signals and pathways

22 September 2017

1 reference

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Viral protein R regulates docking of the HIV-1 preintegration complex to the nuclear pore complex

22 September 2017

1 reference

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Efficient HIV-1 replication can occur in the absence of the viral matrix protein

22 September 2017

1 reference

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Viral protein R regulates nuclear import of the HIV-1 pre-integration complex

22 September 2017

1 reference

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HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection

22 September 2017

1 reference

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HIV-1 infection of non-dividing cells: evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import.

22 September 2017

1 reference

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HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway

22 September 2017

1 reference

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Nuclear import, virion incorporation, and cell cycle arrest/differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr.

22 September 2017

1 reference

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Human immunodeficiency virus type 1 preintegration complexes: studies of organization and composition

22 September 2017

1 reference

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Lack of integrase can markedly affect human immunodeficiency virus type 1 particle production in the presence of an active viral protease

22 September 2017

1 reference

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In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

22 September 2017

1 reference

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Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import

22 September 2017

1 reference

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Distinct effects in primary macrophages and lymphocytes of the human immunodeficiency virus type 1 accessory genes vpr, vpu, and nef: mutational analysis of a primary HIV-1 isolate

22 September 2017

1 reference

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Reduced nuclear import of human immunodeficiency virus type 1 preintegration complexes in the presence of a prototypic nuclear targeting signal

22 September 2017

1 reference

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A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells

22 September 2017

1 reference

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The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells

22 September 2017

1 reference

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The nuclear localization signal of the matrix protein of human immunodeficiency virus type 1 allows the establishment of infection in macrophages and quiescent T lymphocytes

22 September 2017

1 reference

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Integrase mutants of human immunodeficiency virus type 1 with a specific defect in integration.

22 September 2017

1 reference

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Role of the basic domain of human immunodeficiency virus type 1 matrix in macrophage infection

22 September 2017

1 reference

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Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection

22 September 2017

1 reference

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Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes

22 September 2017

1 reference

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Determination of viral proteins present in the human immunodeficiency virus type 1 preintegration complex.

22 September 2017

1 reference

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Active nuclear import of human immunodeficiency virus type 1 preintegration complexes

22 September 2017

1 reference

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Interaction between human immunodeficiency virus type 1 reverse transcriptase and integrase proteins

22 September 2017

1 reference

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Nuclear localization of human immunodeficiency virus type 1 integrase expressed as a fusion protein with green fluorescent protein.

25 September 2017

1 reference

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Cyclophilin A-dependent restriction of human immunodeficiency virus type 1 capsid mutants for infection of nondividing cells

25 September 2017

1 reference

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HIV-1 DNA Flap formation promotes uncoating of the pre-integration complex at the nuclear pore

25 September 2017

1 reference

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Transduction of nondividing human macrophages with gammaretrovirus-derived vectors

15 June 2018

1 reference

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A peptide derived from the N-terminal region of HIV-1 Vpr promotes nuclear import in permeabilized cells: elucidation of the NLS region of the Vpr.

15 June 2018

1 reference

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Human immunodeficiency virus infection of cells arrested in the cell cycle

15 June 2018

1 reference

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Direct Vpr-Vpr interaction in cells monitored by two photon fluorescence correlation spectroscopy and fluorescence lifetime imaging

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

Transportin-SR2 imports HIV into the nucleus

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

SIVMAC Vpx improves the transduction of dendritic cells with nonintegrative HIV-1-derived vectors.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

Interaction of human immunodeficiency virus type 1 integrase with cellular nuclear import receptor importin 7 and its impact on viral replication

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

Importin-alpha promotes passage through the nuclear pore complex of human immunodeficiency virus type 1 Vpr.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

Nuclear localization of Vpr is crucial for the efficient replication of HIV-1 in primary CD4+ T cells

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

Nuclear trafficking of macromolecules by an oligopeptide derived from Vpr of human immunodeficiency virus type-1.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

A synthetic peptide bearing the HIV-1 integrase 161-173 amino acid residues mediates active nuclear import and binding to importin alpha: characterization of a functional nuclear localization signal.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

Characterization of a human immunodeficiency virus type 1 pre-integration complex in which the majority of the cDNA is resistant to DNase I digestion

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

HIV-1 infection requires a functional integrase NLS.

20 August 2018

1 reference

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The HIV-1 DNA flap stimulates HIV vector-mediated cell transduction in the brain.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

Characterization of the nuclear import pathway for HIV-1 integrase.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

The human immunodeficiency virus type-1 central DNA flap is a crucial determinant for lentiviral vector nuclear import and gene transduction of human hematopoietic stem cells

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

Cellular Distribution and Karyophilic Properties of Matrix, Integrase, and Vpr Proteins from the Human and Simian Immunodeficiency Viruses

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798343

The central PPT of the yeast retrotransposon Ty1 is not essential for transposition

2 December 2018

1 reference

12 December 2020

Characterization of HIV replication complexes early after cell-to-cell infection

1 reference

12 December 2020

HIV-1 infection of non-dividing cells

1 reference

12 December 2020

Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability

1 reference

12 December 2020

Phenotype of HIV-1 lacking a functional nuclear localization signal in matrix protein of gag and Vpr is comparable to wild-type HIV-1 in primary macrophages

1 reference

12 December 2020

HIV-1 genome nuclear import is mediated by a central DNA flap

1 reference

12 December 2020

Two nuclear localization signals in the HIV-1 matrix protein regulate nuclear import of the HIV-1 pre-integration complex

1 reference

12 December 2020

HIV-1 reverse transcriptase and integrase enzymes physically interact and inhibit each other

1 reference

12 December 2020

Identifiers

DOI

10.1128/JVI.01952-09

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19889772%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19889772%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference