Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein (Q39791587)

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scientific article published on 5 October 2009

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English	Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein	scientific article published on 5 October 2009

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scholarly article

1 reference

Europe PubMed Central

14 September 2017

Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein (English)

1 reference

Europe PubMed Central

14 September 2017

1 reference

based on heuristic

inferred from title

protein ubiquitination

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based on heuristic

inferred from title

author name string

M R Abedini

1

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Europe PubMed Central

14 September 2017

E J Muller

2

1 reference

Europe PubMed Central

14 September 2017

R Bergeron

3

1 reference

Europe PubMed Central

14 September 2017

D A Gray

4

1 reference

Europe PubMed Central

14 September 2017

B K Tsang

5

1 reference

Europe PubMed Central

14 September 2017

language of work or name

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publication date

5 October 2009

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Europe PubMed Central

14 September 2017

1 reference

Europe PubMed Central

14 September 2017

29

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Europe PubMed Central

14 September 2017

11-25

1 reference

Europe PubMed Central

14 September 2017

1

1 reference

Europe PubMed Central

14 September 2017

https://scigraph.springernature.com/pub.10.1038/onc.2009.300

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Cisplatin induces p53-dependent FLICE-like inhibitory protein ubiquitination in ovarian cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Possible role of FLICE-like inhibitory protein (FLIP) in chemoresistant ovarian cancer cells in vitro.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

TRAIL-induced apoptosis in human vascular endothelium is regulated by phosphatidylinositol 3-kinase/Akt through the short form of cellular FLIP and Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

p53 alterations are predictive of chemoresistance and aggressiveness in ovarian carcinomas: a molecular and immunohistochemical study

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Influence of TRP53 status on FAS membrane localization, CFLAR (c-FLIP) ubiquitinylation, and sensitivity of GC-2spd (ts) cells to undergo FAS-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Role of X-linked inhibitor of apoptosis protein in chemoresistance in ovarian cancer: possible involvement of the phosphoinositide-3 kinase/Akt pathway.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP).

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Akt promotes cisplatin resistance in human ovarian cancer cells through inhibition of p53 phosphorylation and nuclear function

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Accelerated degradation of cellular FLIP protein through the ubiquitin-proteasome pathway in p53-mediated apoptosis of human cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Up-regulation of FLIP in cisplatin-selected HeLa cells causes cross-resistance to CD95/Fas death signalling

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Apoptosis and chemoresistance in human ovarian cancer: is Xiap a determinant?

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Fever-like hyperthermia controls T Lymphocyte persistence by inducing degradation of cellular FLIPshort.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

A novel site of AKT-mediated phosphorylation in the human MDM2 onco-protein

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Rapid up-regulation of c-FLIP expression by BCR signaling through the PI3K/Akt pathway inhibits simultaneously induced Fas-mediated apoptosis in murine B lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Met signals hepatocyte survival by preventing Fas-triggered FLIP degradation in a PI3k-Akt-dependent manner.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Glycine receptors and GABA receptor alpha 1 and gamma 2 subunits during the development of mouse hypoglossal nucleus

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Low glucose-enhanced TRAIL cytotoxicity is mediated through the ceramide-Akt-FLIP pathway

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Upregulation of FLIP(S) by Akt, a possible inhibition mechanism of TRAIL-induced apoptosis in human gastric cancers

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Rapid turnover of c-FLIPshort is determined by its unique C-terminal tail

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Sustained suppression of Fas ligand expression in cisplatin-resistant human ovarian surface epithelial cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

PIK3CA is implicated as an oncogene in ovarian cancer.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

The Akt-regulated Forkhead Transcription Factor FOXO3a Controls Endothelial Cell Viability through Modulation of the Caspase-8 Inhibitor FLIP

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Costimulation by CD137/4-1BB inhibits T cell apoptosis and induces Bcl-xL and c-FLIP(short) via phosphatidylinositol 3-kinase and AKT/protein kinase B.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

Phosphatidylinositol 3-kinase/Akt signaling controls endothelial cell sensitivity to Fas-mediated apoptosis via regulation of FLICE-inhibitory protein (FLIP).

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

21 January 2018

CCAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction and ubiquitin/proteasome-mediated cellular FLICE-inhibitory protein down-regulation contribute to enhancement of tumor necrosis factor-related apoptosis-inducing

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

31 March 2020

Human ovarian cancer and cisplatin resistance: possible role of inhibitor of apoptosis proteins

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

31 March 2020

Down-regulation of c-FLIP increases reactive oxygen species, induces phosphorylation of serine/threonine kinase Akt, and impairs motility of cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

31 March 2020

Akt-mediated cisplatin resistance in ovarian cancer: modulation of p53 action on caspase-dependent mitochondrial death pathway

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

31 March 2020

c-FLIP downregulation contributes to apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me) in human lung cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

31 March 2020

Cisplatin Resistance in an Ovarian Carcinoma Is Associated With a Defect in Programmed Cell Death Control Through XIAP Regulation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.300

7 January 2021

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inferred from DOI database lookup

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10.1038/ONC.2009.300

1 reference

Europe PubMed Central

14 September 2017

release_v2bjlwas5nblhhvdqjcqltkbli

0 references

1 reference

Europe PubMed Central

14 September 2017

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