Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways. (Q39791629)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802005%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways (English)

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9 February 2020

2

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9 February 2020

author name string

R van Amerongen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802005%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

J-P Lambooij

3

1 reference

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9 February 2020

N Proost

4

1 reference

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9 February 2020

J Jonkers

5

1 reference

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9 February 2020

A Berns

6

1 reference

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9 February 2020

language of work or name

English

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publication date

5 October 2009

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9 February 2020

1 reference

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9 February 2020

volume

29

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9 February 2020

issue

1

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9 February 2020

page(s)

93-104

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The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation

9 February 2020

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Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas

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In vivo analysis of Frat1 deficiency suggests compensatory activity of Frat3

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CKIepsilon/discs overgrown promotes both Wnt-Fz/beta-catenin and Fz/PCP signaling in Drosophila

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Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1.

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Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

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Planar polarity is positively regulated by casein kinase Iepsilon in Drosophila

21 January 2018

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A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin

21 January 2018

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Frat is dispensable for canonical Wnt signaling in mammals

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The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling

31 March 2020

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