Synergistic proapoptotic effects of the two tyrosine kinase inhibitors pazopanib and lapatinib on multiple carcinoma cell lines (Q39800101)

14 September 2017

Synergistic proapoptotic effects of the two tyrosine kinase inhibitors pazopanib and lapatinib on multiple carcinoma cell lines (English)

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14 September 2017

11

G Kroemer

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Jean-Charles Soria

10

object named as

J-C Soria

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Ilio Vitale

5

object named as

I Vitale

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author name string

K A Olaussen

1

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14 September 2017

F Commo

2

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14 September 2017

M Tailler

3

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14 September 2017

L Lacroix

4

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14 September 2017

I Vitale

5

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14 September 2017

S Q Raza

6

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14 September 2017

C Richon

7

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14 September 2017

P Dessen

8

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14 September 2017

V Lazar

9

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14 September 2017

J-C Soria

10

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14 September 2017

language of work or name

English

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publication date

14 September 2009

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14 September 2017

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14 September 2017

28

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14 September 2017

4249-4260

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14 September 2017

48

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https://scigraph.springernature.com/pub.10.1038/onc.2009.277

14 September 2017

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cites work

Epidermal growth factor receptor family tyrosine kinases as signal integrators and therapeutic targets

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Vascular endothelial growth factor receptor-1 contributes to resistance to anti-epidermal growth factor receptor drugs in human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Dual inhibition of EGFR and VEGFR pathways in combination with irradiation: antitumour supra-additive effects on human head and neck cancer xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Drug Insight: intracellular inhibitors of HER2--clinical development of lapatinib in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Apoptosis regulation in tetraploid cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Quantitation of mitochondrial alterations associated with apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

EGFR antagonists in cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Drug development of MET inhibitors: targeting oncogene addiction and expedience

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Differential control of G0 programme in chronic lymphocytic leukaemia: a novel prognostic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Controlling cell growth and survival through regulated nutrient transporter expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Elevated levels of glucose transport and transporter messenger RNA are induced by ras or src oncogenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Lapatinib plus capecitabine for HER2-positive advanced breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Dual inhibition of focal adhesion kinase and epidermal growth factor receptor pathways cooperatively induces death receptor-mediated apoptosis in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

A novel HSF1-mediated death pathway that is suppressed by heat shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Delineation of molecular mechanisms of sensitivity to lapatinib in breast cancer cell lines using global gene expression profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Antitumor activity of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib (ZD1839, Iressa) in non-small cell lung cancer cell lines correlates with gene copy number and EGFR mutations but not EGFR protein levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Fine mapping of 28S rRNA sites specifically cleaved in cells undergoing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

ErbB-2-induced mammary tumor growth: the role of cyclin D1 and p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Phase I trial of pazopanib in patients with advanced cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Kinomics: methods for deciphering the kinome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Farnesol-induced apoptosis in human lung carcinoma cells is coupled to the endoplasmic reticulum stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

A quantitative analysis of kinase inhibitor selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

The protein kinase complement of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Anaplastic lymphoma kinase is a dependence receptor whose proapoptotic functions are activated by caspase cleavage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Protein kinase inhibitors: insights into drug design from structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Targeting the c-Met signaling pathway in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

The p53 family and programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

HER-2 gene amplification, HER-2 and epidermal growth factor receptor mRNA and protein expression, and lapatinib efficacy in women with metastatic breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

A selective small molecule inhibitor of c-Met, PHA665752, inhibits tumorigenicity and angiogenesis in mouse lung cancer xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Synergism of EGFR and c-Met pathways, cross-talk and inhibition, in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Randomized phase II study of pulse erlotinib before or after carboplatin and paclitaxel in current or former smokers with advanced non-small-cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Inhibition of multiple vascular endothelial growth factor receptors (VEGFR) blocks lymph node metastases but inhibition of VEGFR-2 is sufficient to sensitize tumor cells to platinum-based chemotherapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Drug Insight: gastrointestinal stromal tumors (GIST)--the solid tumor model for cancer-specific treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Pazopanib, a potent orally administered small-molecule multitargeted tyrosine kinase inhibitor for renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Phase I dose escalation and pharmacokinetic study of lapatinib in combination with trastuzumab in patients with advanced ErbB2-positive breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Identification of the apoptosis activation cascade induced in mammary carcinomas by energy restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

limmaGUI: a graphical user interface for linear modeling of microarray data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Differential gene expression detection and sample classification using penalized linear regression models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Methods to measure membrane potential and permeability transition in the mitochondria during apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Inverse prognostic impact of angiogenic marker expression in tumor cells versus stromal cells in non small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Expression and function of vascular endothelial growth factor receptor-1 on human colorectal cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Development and validation of a sensitive assay for the quantification of imatinib using LC/LC-MS/MS in human whole blood and cell culture

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

Caspase-3-dependent and -independent degradation of 28 S ribosomal RNA may be involved in the inhibition of protein synthesis during apoptosis initiated by death receptor engagement

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.277

31 March 2020

Identifiers

DOI

10.1038/ONC.2009.277

1 reference

Dimensions Publication ID

14 September 2017

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1 reference