Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression (Q39800990)

14 September 2017

Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression (English)

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14 September 2017

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5

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14 September 2017

Sven Sewitz

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author name string

Himesh Fernando

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14 September 2017

Jeremy Darot

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14 September 2017

Simon Tavaré

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14 September 2017

Shankar Balasubramanian

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14 September 2017

language of work or name

English

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publication date

10 September 2009

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14 September 2017

Nucleic Acids Research

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14 September 2017

37

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14 September 2017

20

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14 September 2017

6716-6722

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describes a project that uses

14 September 2017

limma

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22 June 2022

https://europepmc.org/article/PMC/2777450

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Four-stranded nucleic acids: structure, function and targeting of G-quadruplexes

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Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions

22 September 2017

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G-quadruplexes: targets in anticancer drug design.

22 September 2017

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Genome-wide analysis reveals regulatory role of G4 DNA in gene transcription

22 September 2017

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Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae.

22 September 2017

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Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics

22 September 2017

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22 September 2017

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Tetraplex DNA and its interacting proteins

22 September 2017

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Structure of an Unprecedented G-Quadruplex Scaffold in the Human c-kit Promoter

22 September 2017

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Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives

22 September 2017

1 reference

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Physiological relevance of telomeric G-quadruplex formation: a potential drug target

22 September 2017

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Quadruplex DNA: sequence, topology and structure

22 September 2017

1 reference

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G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription.

22 September 2017

1 reference

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

22 September 2017

1 reference

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Deconvoluting the structural and drug-recognition complexity of the G-quadruplex-forming region upstream of the bcl-2 P1 promoter

22 September 2017

1 reference

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Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo

22 September 2017

1 reference

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BioMart and Bioconductor: a powerful link between biological databases and microarray data analysis

22 September 2017

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Prevalence of quadruplexes in the human genome

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

A novel, high-performance random array platform for quantitative gene expression profiling

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

Propeller-type parallel-stranded G-quadruplexes in the human c-myc promoter

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

New perspectives on connecting messenger RNA 3' end formation to transcription

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

Structure of a G-quadruplex-ligand complex

22 September 2017

1 reference

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The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivo

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

Crystal structure of the potassium form of an Oxytricha nova G-quadruplex

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

Crystal structure of parallel quadruplexes from human telomeric DNA

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

A double chain reversal loop and two diagonal loops define the architecture of a unimolecular DNA quadruplex containing a pair of stacked G(syn)-G(syn)-G(anti)-G(anti) tetrads flanked by a G-(T-T) Triad and a T-T-T triple

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

Selection of zinc fingers that bind single-stranded telomeric DNA in the G-quadruplex conformation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

DNA tetraplex formation in the control region of c-myc

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

G-quadruplex nucleic acids as therapeutic targets

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

G-quadruplexes in promoters throughout the human genome

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

Putative DNA quadruplex formation within the human c-kit oncogene

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

Inhibition of human telomerase activity by an engineered zinc finger protein that binds G-quadruplexes.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

G-quadruplexes: the beginning and end of UTRs

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

Genome-wide computational and expression analyses reveal G-quadruplex DNA motifs as conserved cis-regulatory elements in human and related species.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

Selective recognition of a DNA G-quadruplex by an engineered antibody

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

Exploring the recognition of quadruplex DNA by an engineered Cys2-His2 zinc finger protein

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

PlasmodiumTelomeric Sequences: Structure, Stability and Quadruplex Targeting by Small Compounds

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777450

2 December 2018

Identifiers

DOI

10.1093/NAR/GKP740

1 reference

14 September 2017

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14 September 2017

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