Nuclear EGFR contributes to acquired resistance to cetuximab (Q39812008)

14 September 2017

Nuclear EGFR contributes to acquired resistance to cetuximab (English)

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14 September 2017

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C Li

1

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14 September 2017

M Iida

2

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14 September 2017

E F Dunn

3

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14 September 2017

A J Ghia

4

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14 September 2017

D L Wheeler

5

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14 September 2017

language of work or name

English

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publication date

17 August 2009

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14 September 2017

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14 September 2017

28

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43

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14 September 2017

3801-3813

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describes a project that uses

14 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2900381/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/onc.2009.234

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cites work

Epidermal growth factor receptor cooperates with Src family kinases in acquired resistance to cetuximab.

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Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer

22 September 2017

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Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression

22 September 2017

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Mechanisms of acquired resistance to cetuximab: role of HER (ErbB) family members

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900381

Human breast cancer cells selected for resistance to trastuzumab in vivo overexpress epidermal growth factor receptor and ErbB ligands and remain dependent on the ErbB receptor network

22 September 2017

1 reference

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A novel mechanism of resistance to epidermal growth factor receptor antagonism in vivo

22 September 2017

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Role of the Sec61 translocon in EGF receptor trafficking to the nucleus and gene expression

22 September 2017

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Tyrosine phosphorylation controls PCNA function through protein stability

22 September 2017

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Nuclear-cytoplasmic transport of EGFR involves receptor endocytosis, importin beta1 and CRM1.

22 September 2017

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Interaction of the epidermal growth factor receptor and the DNA-dependent protein kinase pathway following gefitinib treatment

22 September 2017

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Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival.

22 September 2017

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Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor

22 September 2017

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Co-regulation of B-Myb expression by E2F1 and EGF receptor

22 September 2017

1 reference

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EGFR signaling pathway in breast cancers: from traditional signal transduction to direct nuclear translocalization.

22 September 2017

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Quantitative determination of nuclear and cytoplasmic epidermal growth factor receptor expression in oropharyngeal squamous cell cancer by using automated quantitative analysis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900381

Intrinsic and acquired resistance to EGFR inhibitors in human cancer therapy.

22 September 2017

1 reference

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Differential effects of gefitinib and cetuximab on non-small-cell lung cancers bearing epidermal growth factor receptor mutations

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900381

Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900381

Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900381

Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900381

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

22 September 2017

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Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor

22 September 2017

1 reference

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Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer.

22 September 2017

1 reference

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Binding at and transactivation of the COX-2 promoter by nuclear tyrosine kinase receptor ErbB-2

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900381

Acquired resistance to EGFR inhibitors: mechanisms and prevention strategies

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900381

TACE is required for the activation of the EGFR by TGF-alpha in tumors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900381

c-erbB-3: a nuclear protein in mammary epithelial cells.

22 September 2017

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Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability

22 September 2017

1 reference

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gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase

22 September 2017

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Untangling the ErbB signalling network

22 September 2017

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Local recurrence in head and neck cancer: relationship to radiation resistance and signal transduction.

22 September 2017

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Nuclear localization of EGF receptor and its potential new role as a transcription factor

25 September 2017

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Nuclear localization of p185neu tyrosine kinase and its association with transcriptional transactivation

25 September 2017

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Localization of epidermal growth factor receptor in hepatocyte nuclei

25 September 2017

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Correlates and determinants of nuclear epidermal growth factor receptor content in an oropharyngeal cancer tissue microarray

17 June 2018

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Characterization of a novel tripartite nuclear localization sequence in the EGFR family.

20 August 2018

1 reference

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EGF receptor as a therapeutic target: patient selection and mechanisms of resistance to receptor-targeted drugs.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900381

Micronutrient sprinkles to control childhood anaemia

20 August 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.234

Physical interaction between epidermal growth factor receptor and DNA-dependent protein kinase in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.234

Functional nuclear epidermal growth factor receptors in human choriocarcinoma JEG-3 cells and normal human placenta

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.234

Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the anti-EGFR monoclonal antibody cetuximab

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.234

The developing role of receptors and adaptors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.234

Effective intravenous therapy of murine pulmonary metastases with an oncolytic herpes virus expressing interleukin 12

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.234

Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: a role for altered tumor angiogenesis

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19684613

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2009.234

1 reference

14 September 2017

1 reference

14 September 2017

1 reference