Mechanisms and kinetics of human arylamine N-acetyltransferase 1 inhibition by disulfiram (Q39815342)

14 September 2017

title

Mechanisms and kinetics of human arylamine N-acetyltransferase 1 inhibition by disulfiram (English)

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14 September 2017

Florence Malka

1

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14 September 2017

Julien Dairou

2

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14 September 2017

Nilusha Ragunathan

3

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14 September 2017

Jean-Marie Dupret

4

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14 September 2017

Fernando Rodrigues-Lima

5

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14 September 2017

language of work or name

English

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publication date

31 July 2009

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volume

276

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issue

17

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14 September 2017

page(s)

4900-4908

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In vivo inhibition of aldehyde dehydrogenase by disulfiram

14 September 2017

cites work

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Human aldehyde dehydrogenase: mechanism of inhibition of disulfiram

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Disulfiram is a potent in vitro inhibitor of DNA topoisomerases.

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Inhibition of Invasion and Angiogenesis by Zinc-Chelating Agent Disulfiram

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Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity

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Effect of chronic disulfiram administration on the activities of CYP1A2, CYP2C19, CYP2D6, CYP2E1, and N-acetyltransferase in healthy human subjects

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Structure and regulation of the drug-metabolizing enzymes arylamine N-acetyltransferases

21 January 2018

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Skeletal Muscles Express the Xenobiotic-metabolizing Enzyme ArylamineN-acetyltransferase

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Arylamine N-acetyltransferases.

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Effect of environmental substances on the activity of arylamine N-acetyltransferases

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Redox regulation of the human xenobiotic metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1). Reversible inactivation by hydrogen peroxide

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Regulation of the activity of the human drug metabolizing enzyme arylamine N-acetyltransferase 1: role of genetic and non genetic factors

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The xenobiotic-metabolizing enzymes arylamine N-acetyltransferases in human lens epithelial cells: inactivation by cellular oxidants and UVB-induced oxidative stress.

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Identification of the xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 as a new target of cisplatin in breast cancer cells: molecular and cellular mechanisms of inhibition.

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Induction of human arylamine N-acetyltransferase type I by androgens in human prostate cancer cells

21 January 2018

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Arylamine N-acetyltransferase 1 expression in breast cancer cell lines: a potential marker in estrogen receptor-positive tumors

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Peroxynitrite irreversibly inactivates the human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1) in human breast cancer cells: a cellular and mechanistic study

21 January 2018

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Overview--in vitro inhibition of aldehyde dehydrogenase by disulfiram and metabolites

21 January 2018

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Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases

21 January 2018

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Mechanism of inactivation of sheep liver cytoplasmic aldehyde dehydrogenase by disulfiram

21 January 2018

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Inactivation of human arylamine N-acetyltransferase 1 by hydrogen peroxide and peroxynitrite

21 January 2018

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21 January 2018

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Acetylation of p-aminobenzoylglutamate, a folic acid catabolite, by recombinant human arylamine N-acetyltransferase and U937 cells

21 January 2018

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Deletion of a xenobiotic metabolizing gene in mice affects folate metabolism.

21 January 2018

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The COOH terminus of arylamine N-acetyltransferase from Salmonella typhimurium controls enzymic activity

21 January 2018

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21 January 2018

Identifiers

DOI

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14 September 2017

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