Inducible endothelial cell-specific gene expression in transgenic mouse embryos and adult mice (Q39834303)

15 September 2017

Inducible endothelial cell-specific gene expression in transgenic mouse embryos and adult mice (English)

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15 September 2017

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Urban Deutsch

1

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15 September 2017

Thorsten M Schlaeger

2

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15 September 2017

Bénédicte Dehouck

3

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15 September 2017

Axinia Döring

4

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15 September 2017

Silke Tauber

5

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15 September 2017

Werner Risau

6

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15 September 2017

Britta Engelhardt

7

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15 September 2017

language of work or name

English

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publication date

15 January 2008

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Experimental Cell Research

15 September 2017

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15 September 2017

314

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15 September 2017

6

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15 September 2017

1202-1216

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Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development

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Vascular-specific growth factors and blood vessel formation

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Conditional control of gene expression in the mouse

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Recent innovations in tissue-specific gene modifications in the mouse

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VE-Cadherin-Cre-recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells.

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VE-cadherin-CreERT2 transgenic mouse: a model for inducible recombination in the endothelium.

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Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

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The lac operator-repressor system is functional in the mouse

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Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter.

7 January 2021

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Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice

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Tet repressor-based system for regulated gene expression in eukaryotic cells: principles and advances

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A fluorescent Tie1 reporter allows monitoring of vascular development and endothelial cell isolation from transgenic mouse embryos

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The human ICAM-2 promoter is endothelial cell-specific in vitro and in vivo and contains critical Sp1 and GATA binding sites

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Targeting gene expression to endothelium in transgenic animals: a comparison of the human ICAM-2, PECAM-1 and endoglin promoters

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Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice

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E- and P-selectin are not required for the development of experimental autoimmune encephalomyelitis in C57BL/6 and SJL mice

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Characterization of the chicken beta-globin insulator

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MAdCAM-1 has homology to immunoglobulin and mucin-like adhesion receptors and to IgA1

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A lymphoid cell surface glycoprotein involved in endothelial cell recognition and lymphocyte homing in man.

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Only simultaneous blocking of the L- and P-selectin completely inhibits neutrophil migration into mouse peritoneum

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Species-specific and conserved epitopes on mouse and human E-selectin important for leukocyte adhesion

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Recent advances in inducible expression in transgenic mice

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Of mice and models: improved animal models for biomedical research

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

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Transcriptional activation by tetracyclines in mammalian cells

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Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential

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Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity

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Transgenic animals with inducible, targeted gene expression in brain.

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Insulators and boundaries: versatile regulatory elements in the eukaryotic genome

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Prospects and implications of using chromatin insulators in gene therapy and transgenesis

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Insulators: exploiting transcriptional and epigenetic mechanisms

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Homogeneity and long-term stability of tetracycline-regulated gene expression with low basal activity by using the rtTA2S-M2 transactivator and insulator-flanked reporter vectors

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1 reference

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Conditional transgene expression in endothelial cells.

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Functional determinants for the tetracycline-dependent transactivator tTA in transgenic mouse embryos

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Inducible and selective transgene expression in murine vascular endothelium

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Transgenic targeting with regulatory elements of the human CD34 gene

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Microvascular patterning is controlled by fine-tuning the Akt signal

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Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice

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High level of endothelial cell-specific gene expression by a combination of the 5' flanking region and the 5' half of the first intron of the VE-cadherin gene.

7 January 2021

1 reference

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Specific Induction of tie1 Promoter by Disturbed Flow in Atherosclerosis-Prone Vascular Niches and Flow-Obstructing Pathologies

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10.1016/J.YEXCR.2007.12.026

7 January 2021

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15 September 2017

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