Compensatory mutations in NS3 and NS5A proteins enhance the virus production capability of hepatitis C reporter virus (Q39835772)

15 September 2017

Compensatory mutations in NS3 and NS5A proteins enhance the virus production capability of hepatitis C reporter virus (English)

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15 September 2017

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Qingxia Han

1

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15 September 2017

Chunlian Xu

2

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15 September 2017

Chunchen Wu

3

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15 September 2017

Wenbo Zhu

4

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15 September 2017

Rongge Yang

5

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15 September 2017

Xinwen Chen

6

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15 September 2017

18 June 2009

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15 September 2017

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15 September 2017

145

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15 September 2017

1

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15 September 2017

63-73

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Uncleaved NS2-3 is required for production of infectious bovine viral diarrhea virus

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Robust production of infectious viral particles in Huh-7 cells by introducing mutations in hepatitis C virus structural proteins

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Differential Biophysical Properties of Infectious Intracellular and Secreted Hepatitis C Virus Particles

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Robust hepatitis C genotype 3a cell culture releasing adapted intergenotypic 3a/2a (S52/JFH1) viruses.

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Phosphorylation of hepatitis C virus NS5A nonstructural protein: a new paradigm for phosphorylation-dependent viral RNA replication?

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The Hepatitis C Virus NS4B Protein Can trans-Complement Viral RNA Replication and Modulates Production of Infectious Virus

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In vivo determination of substrate specificity of hepatitis C virus NS3 protease: genetic assay for site-specific proteolysis

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Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations

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Mutations in the Yellow Fever Virus Nonstructural Protein NS2A Selectively Block Production of Infectious Particles

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Two novel conserved motifs in the hepatitis C virus NS3 protein critical for helicase action

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Complete replication of hepatitis C virus in cell culture

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Insertion and deletion analyses identify regions of non-structural protein 5A of Hepatitis C virus that are dispensable for viral genome replication.

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Analysis of adaptive mutations in Kunjin virus replicon RNA reveals a novel role for the flavivirus nonstructural protein NS2A in inhibition of beta interferon promoter-driven transcription

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Complementation analysis of the flavivirus Kunjin NS3 and NS5 proteins defines the minimal regions essential for formation of a replication complex and shows a requirement of NS3 in cis for virus assembly

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NS3 Helicase Domains Involved in Infectious Intracellular Hepatitis C Virus Particle Assembly

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Hepatitis C virus NS5A: tales of a promiscuous protein

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Interaction of Hepatitis C Virus Nonstructural Protein 5A with Core Protein Is Critical for the Production of Infectious Virus Particles

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The lipid droplet is an important organelle for hepatitis C virus production

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Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes

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Architects of assembly: roles of Flaviviridae non-structural proteins in virion morphogenesis

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An infectious West Nile virus that expresses a GFP reporter gene.

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Analysis of Hepatitis C Virus Superinfection Exclusion by Using Novel Fluorochrome Gene-Tagged Viral Genomes

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Regulation of Hepatitis C Virion Production via Phosphorylation of the NS5A Protein

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Identification of Residues Required for RNA Replication in Domains II and III of the Hepatitis C Virus NS5A Protein

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The NS5A protein of hepatitis C virus is a zinc metalloprotein

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Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

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Compensatory Mutations in E1, p7, NS2, and NS3 Enhance Yields of Cell Culture-Infectious Intergenotypic Chimeric Hepatitis C Virus

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Robust hepatitis C virus infection in vitro

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Persistent Hepatitis C Virus Infection In Vitro: Coevolution of Virus and Host

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10.1016/J.VIRUSRES.2009.06.005

7 January 2021

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DOI

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15 September 2017

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