Conditional Deletion of Hsd11b2 in the Brain Causes Salt Appetite and Hypertension (Q39842428)

15 September 2017

Conditional Deletion of Hsd11b2 in the Brain Causes Salt Appetite and Hypertension (English)

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15 September 2017

arterial hypertension

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Caitlin S Wyrwoll

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John Mullins

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Matthew A Bailey

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1 June 2020

author name string

Louise C Evans

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Julie A McNairn

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Robert I Menzies

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Thorbjørn H Christensen

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Emad A S Al-Dujaili

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Christopher J Kenyon

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Jonathan R Seckl

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Megan C Holmes

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language of work or name

English

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publication date

7 March 2016

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15 September 2017

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1 June 2020

volume

133

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page(s)

1360-1370

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issue

14

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Fetal brain 11β-hydroxysteroid dehydrogenase type 2 selectively determines programming of adult depressive-like behaviors and cognitive function, but not anxiety behaviors in male mice.

1 June 2020

cites work

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Glucocorticoids and 11β-hydroxysteroid dehydrogenases: mechanisms for hypertension

22 September 2017

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Hypertrophy in the Distal Convoluted Tubule of an 11β-Hydroxysteroid Dehydrogenase Type 2 Knockout Model

22 September 2017

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22 September 2017

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Salt-induced hypertension in a mouse model of Liddle syndrome is mediated by epithelial sodium channels in the brain

22 September 2017

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Failure to downregulate the epithelial sodium channel causes salt sensitivity in Hsd11b2 heterozygote mice.

22 September 2017

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22 September 2017

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Glucocorticoid receptor is indispensable for physiological responses to aldosterone in epithelial Na+ channel induction via the mineralocorticoid receptor in a human colonic cell line

22 September 2017

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Hsd11b2 haploinsufficiency in mice causes salt sensitivity of blood pressure.

22 September 2017

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Effects of ACTH, dexamethasone, and adrenalectomy on 11beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) gene expression in the rat central nervous system

22 September 2017

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A switch in the mechanism of hypertension in the syndrome of apparent mineralocorticoid excess

22 September 2017

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Identification of polymorphisms in the human 11beta-hydroxysteroid dehydrogenase type 2 gene promoter: functional characterization and relevance for salt sensitivity.

22 September 2017

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Aldosterone target neurons in the nucleus tractus solitarius drive sodium appetite.

22 September 2017

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22 September 2017

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Hypertension in mice lacking 11beta-hydroxysteroid dehydrogenase type 2.

22 September 2017

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Syndrome of apparent mineralocorticoid excess. A defect in the cortisol-cortisone shuttle

22 September 2017

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22 September 2017

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25 September 2017

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25 September 2017

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Glucocorticoids facilitate mineralocorticoid-induced sodium intake in the rat.

15 June 2018

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15 June 2018

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Intracerebroventricular infusion of aldosterone induces hypertension in rats.

15 June 2018

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15 June 2018

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15 June 2018

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15 June 2018

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20 August 2018

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20 August 2018

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20 August 2018

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20 August 2018

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Analysis of the 11beta-hydroxysteroid dehydrogenase type 2 gene (HSD11B2) in human essential hypertension

20 August 2018

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20 August 2018

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20 August 2018

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20 August 2018

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20 August 2018

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20 August 2018

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12 December 2020

Mineralocorticoid excess or glucocorticoid insufficiency: renal and metabolic phenotypes in a rat Hsd11b2 knockout model

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12 December 2020

Remission of hypertension and electrolyte abnormalities following renal transplantation in a patient with apparent mineralocorticoid excess well documented throughout childhood

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12 December 2020

EVAluation of the prognostic value of BARoreflex sensitivity in hypertensive patients: the EVABAR study

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12 December 2020

HSD11B2 CA-repeat and sodium balance

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12 December 2020

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Messenger RNAs encoding steroidogenic enzymes are expressed in rodent brain

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Aldosterone impairs baroreflex sensitivity in healthy adults

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12 December 2020

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12 December 2020

10.1161/CIRCULATIONAHA.115.019341

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