Not all hERG pore domain mutations have a severe phenotype: G584S has an inactivation gating defect with mild phenotype compared to G572S, which has a dominant negative trafficking defect and a severe phenotype (Q39843866)
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| Language | Label | Description | Also known as |
|---|---|---|---|
| English | Not all hERG pore domain mutations have a severe phenotype: G584S has an inactivation gating defect with mild phenotype compared to G572S, which has a dominant negative trafficking defect and a severe phenotype |
scientific article |
Statements
Not all hERG pore domain mutations have a severe phenotype: G584S has an inactivation gating defect with mild phenotype compared to G572S, which has a dominant negative trafficking defect and a severe phenotype (English)
Jonathan R Skinner
Jing Ting Zhao
Adam P Hill
Anthony Varghese
Antony A Cooper
Heikki Swan
Päivi J Laitinen-Forsblom
Terence J Campbell
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1 reference