Axin localizes to mitotic spindles and centrosomes in mitotic cells (Q39866515)

15 September 2017

Axin localizes to mitotic spindles and centrosomes in mitotic cells (English)

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15 September 2017

Shi-Mun Kim

1

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15 September 2017

Eun-Jin Choi

2

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15 September 2017

Ki-Joon Song

3

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15 September 2017

Sewoon Kim

4

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15 September 2017

Eunjeong Seo

5

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15 September 2017

Eek-Hoon Jho

6

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15 September 2017

Sun-Ho Kee

7

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15 September 2017

language of work or name

English

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publication date

30 January 2009

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Experimental Cell Research

15 September 2017

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15 September 2017

315

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15 September 2017

6

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15 September 2017

943-954

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The links between axin and carcinogenesis

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The many ways of Wnt in cancer

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Chromosomal instability by beta-catenin/TCF transcription in APC or beta-catenin mutant cells.

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AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

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Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer

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Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling

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Wnt/beta-catenin signaling in development and disease

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Multinuclear giant cell formation is enhanced by down-regulation of Wnt signaling in gastric cancer cell line, AGS.

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1 reference

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Identification of a role for beta-catenin in the establishment of a bipolar mitotic spindle

7 January 2021

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Mutations in the APC tumour suppressor gene cause chromosomal instability

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APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment

7 January 2021

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A role for glycogen synthase kinase-3 in mitotic spindle dynamics and chromosome alignment

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A role for the Adenomatous Polyposis Coli protein in chromosome segregation

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Mitotic kinases: the key to duplication, segregation, and cytokinesis errors, chromosomal instability, and oncogenesis

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Roles of Aurora kinases in mitosis and tumorigenesis.

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MLN8054, a small-molecule inhibitor of Aurora A, causes spindle pole and chromosome congression defects leading to aneuploidy

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Mitotic requirement for aurora A kinase is bypassed in the absence of aurora B kinase

7 January 2021

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Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

7 January 2021

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Polo-like Kinase 1 Triggers the Initiation of Cytokinesis in Human Cells by Promoting Recruitment of the RhoGEF Ect2 to the Central Spindle

7 January 2021

1 reference

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Axin inhibits extracellular signal-regulated kinase pathway by Ras degradation via beta-catenin.

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Identification of antigenic differences between the phosphorylated and nonphosphorylated forms of the E7 protein of human papillomavirus type 16

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A divergent canonical WNT-signaling pathway regulates microtubule dynamics: dishevelled signals locally to stabilize microtubules

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Mitotic kinases as regulators of cell division and its checkpoints

7 January 2021

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Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.

7 January 2021

1 reference

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Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody

7 January 2021

1 reference

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Requirement of aurora-A kinase in astral microtubule polymerization and spindle microtubule flux

7 January 2021

1 reference

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Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry

7 January 2021

1 reference

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Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells.

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1 reference

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Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos

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Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

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The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

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Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

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Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

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Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors

7 January 2021

1 reference

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Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas

7 January 2021

1 reference

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10.1016/J.YEXCR.2009.01.013

7 January 2021

Identifiers

DOI

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15 September 2017

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