Four of eleven loci required for transient complementation of human cytomegalovirus DNA replication cooperate to activate expression of replication genes. (Q39873107)

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scientific article published on January 1996

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English	Four of eleven loci required for transient complementation of human cytomegalovirus DNA replication cooperate to activate expression of replication genes.	scientific article published on January 1996

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scholarly article

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13 October 2019

Four of eleven loci required for transient complementation of human cytomegalovirus DNA replication cooperate to activate expression of replication genes (English)

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13 October 2019

Cytomegalovirus

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A C Iskenderian

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13 October 2019

L Huang

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A Reilly

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R M Stenberg

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D G Anders

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1 January 1996

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13 October 2019

Journal of Virology

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13 October 2019

70

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1

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383-392

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13 October 2019

Multiple regulatory events influence human cytomegalovirus DNA polymerase (UL54) expression during viral infection

1 reference

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In vitro expression of the human cytomegalovirus DNA polymerase gene: effects of sequence alterations on enzyme activity

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A transcription factor with homology to the AP-1 family links RNA transcription and DNA replication in the lytic cycle of Epstein-Barr virus.

1 reference

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Open reading frames UL44, IRS1/TRS1, and UL36-38 are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA synthesis.

1 reference

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An in vitro system for human cytomegalovirus immediate early 2 protein (IE2)-mediated site-dependent repression of transcription and direct binding of IE2 to the major immediate early promoter

1 reference

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The 86-kilodalton IE-2 protein of human cytomegalovirus is a sequence-specific DNA-binding protein that interacts directly with the negative autoregulatory response element located near the cap site of the IE-1/2 enhancer-promoter.

1 reference

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The human cytomegalovirus 86-kilodalton immediate-early 2 protein: synthesis as a precursor polypeptide and interaction with a 75-kilodalton protein of probable viral origin

1 reference

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22 September 2017

Eleven loci encoding trans-acting factors are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA replication.

1 reference

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Identification of sequence elements in the human cytomegalovirus DNA polymerase gene promoter required for activation by viral gene products.

1 reference

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Identification of binding sites for the 86-kilodalton IE2 protein of human cytomegalovirus within an IE2-responsive viral early promoter.

1 reference

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UL69 of human cytomegalovirus, an open reading frame with homology to ICP27 of herpes simplex virus, encodes a transactivator of gene expression

1 reference

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Use of recombinant virus to assess human cytomegalovirus early and late promoters in the context of the viral genome.

1 reference

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22 September 2017

Transactivation by the human cytomegalovirus IE2 86-kilodalton protein requires a domain that binds to both the TATA box-binding protein and the retinoblastoma protein.

1 reference

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22 September 2017

Site-specific binding of the human cytomegalovirus IE2 86-kilodalton protein to an early gene promoter

1 reference

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Protein-protein interactions between human cytomegalovirus IE2-580aa and pUL84 in lytically infected cells

1 reference

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22 September 2017

Cytomegalovirus-mediated induction of antisense mRNA expression to UL44 inhibits virus replication in an astrocytoma cell line: identification of an essential gene

1 reference

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22 September 2017

Expression of human cytomegalovirus UL36 and UL37 genes is required for viral DNA replication

1 reference

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22 September 2017

Human cytomegalovirus UL102 gene

1 reference

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22 September 2017

Replication of Epstein-Barr virus oriLyt: lack of a dedicated virally encoded origin-binding protein and dependence on Zta in cotransfection assays.

1 reference

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22 September 2017

High-efficiency transformation of mammalian cells by plasmid DNA

1 reference

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22 September 2017

A cytomegalovirus protein with properties of herpes simplex virus ICP8: partial purification of the polypeptide and map position of the gene

1 reference

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22 September 2017

Sequence and transcription analysis of the human cytomegalovirus DNA polymerase gene

1 reference

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22 September 2017

Genomic localization, sequence analysis, and transcription of the putative human cytomegalovirus DNA polymerase gene

1 reference

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22 September 2017

A DNA binding protein specific for an origin of replication of herpes simplex virus type 1.

1 reference

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22 September 2017

2.2-kilobase class of early transcripts encoded by cell-related sequences in human cytomegalovirus strain AD169

1 reference

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22 September 2017

Identification of sequence requirements and trans-acting functions necessary for regulated expression of a human cytomegalovirus early gene.

1 reference

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22 September 2017

Interaction of origin binding protein with an origin of replication of herpes simplex virus 1.

1 reference

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22 September 2017

Location, transcript analysis, and partial nucleotide sequence of the cytomegalovirus gene encoding an early DNA-binding protein with similarities to ICP8 of herpes simplex virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189828

22 September 2017

trans-activation and autoregulation of gene expression by the immediate-early region 2 gene products of human cytomegalovirus

1 reference

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22 September 2017

Identification of herpes simplex virus type 1 genes required for origin-dependent DNA synthesis

1 reference

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Four phosphoproteins with common amino termini are encoded by human cytomegalovirus AD169.

1 reference

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Posttranscriptional regulation of a class of human cytomegalovirus phosphoproteins encoded by an early transcription unit.

1 reference

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Regulation of cytomegalovirus late-gene expression: differential use of three start sites in the transcriptional activation of ICP36 gene expression

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Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element.

1 reference

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Regulated expression of the human cytomegalovirus pp65 gene: octamer sequence in the promoter is required for activation by viral gene products

1 reference

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Herpes simplex virus type 1 gene products required for DNA replication: identification and overexpression.

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Identification of the lytic origin of DNA replication in human cytomegalovirus by a novel approach utilizing ganciclovir-induced chain termination

1 reference

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22 September 2017

The IE2 gene products of human cytomegalovirus specifically down-regulate expression from the major immediate-early promoter through a target sequence located near the cap site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189828

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Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169.

1 reference

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Promoter-specific trans activation and repression by human cytomegalovirus immediate-early proteins involves common and unique protein domains

1 reference

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Transactivation of a human cytomegalovirus early promoter by gene products from the immediate-early gene IE2 and augmentation by IE1: mutational analysis of the viral proteins

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Multicomponent origin of cytomegalovirus lytic-phase DNA replication

1 reference

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A cis-acting element in the major immediate-early (IE) promoter of human cytomegalovirus is required for negative regulation by IE2

1 reference

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The DNA sequence of the human cytomegalovirus genome

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Human cytomegalovirus UL36-38 and US3 immediate-early genes: temporally regulated expression of nuclear, cytoplasmic, and polysome-associated transcripts during infection

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Transactivation of the cytomegalovirus ICP36 gene promoter requires the alpha gene product TRS1 in addition to IE1 and IE2

1 reference

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Human cytomegalovirus US3 and UL36-38 immediate-early proteins regulate gene expression

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trans-acting requirements for replication of Epstein-Barr virus ori-Lyt

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Human cytomegalovirus origin of DNA replication (oriLyt) resides within a highly complex repetitive region

1 reference

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Human cytomegalovirus contains a tegument protein that enhances transcription from promoters with upstream ATF and AP-1 cis-acting elements

1 reference

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Physical and functional interaction of human cytomegalovirus DNA polymerase and its accessory protein (ICP36) expressed in insect cells

1 reference

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Boundaries and structure of human cytomegalovirus oriLyt, a complex origin for lytic-phase DNA replication

1 reference

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Characterization of human cytomegalovirus UL84 early gene and identification of its putative protein product

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Human cytomegalovirus. III. Virus-induced DNA polymerase

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Functional interaction between the HCMV IE2 transactivator and the retinoblastoma protein.

1 reference

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Cytomegalovirus-infected cells contain a DNA-binding protein

1 reference

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Differences in cell-type-specific blocks to immediate early gene expression and DNA replication of human, simian and murine cytomegalovirus

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17 June 2018

Expression of the human cytomegalovirus UL36–38 immediate early region during permissive infection

1 reference

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17 June 2018

Intracellular localization and DNA-binding activity of a class of viral early phosphoproteins in human fibroblasts infected with human cytomegalovirus (Towne strain).

1 reference

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Immunological characterization of an early cytomegalovirus single-strand DNA-binding protein with similarities to the HSV major DNA-binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/8523552

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulatio

1 reference

https://pubmed.ncbi.nlm.nih.gov/8523552

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8523552%20AND%20SRC:MED&resulttype=core&format=json

13 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8523552%20AND%20SRC:MED&resulttype=core&format=json

13 October 2019

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