ERK5 knockdown generates mouse leukemia cells with low MHC class I levels that activate NK cells and block tumorigenesis. (Q39876512)

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22 January 2020

title

ERK5 knockdown generates mouse leukemia cells with low MHC class I levels that activate NK cells and block tumorigenesis (English)

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22 January 2020

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22 January 2020

Johan Garaude

3

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22 January 2020

Martin Villalba

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22 January 2020

author name string

Seyma Charni

1

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22 January 2020

Geoffroy de Bettignies

4

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22 January 2020

Chantal Jacquet

5

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22 January 2020

Robert A Hipskind

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22 January 2020

Dinah Singer

7

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22 January 2020

Alberto Anel

8

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language of work or name

English

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publication date

1 March 2009

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22 January 2020

published in

Journal of Immunology

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22 January 2020

volume

182

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22 January 2020

issue

6

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22 January 2020

page(s)

3398-3405

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Immunogenicity of apoptotic cells in vivo: role of antigen load, antigen-presenting cells, and cytokines

22 January 2020

cites work

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12 December 2020

Recruitment and activation of natural killer (NK) cells in vivo determined by the target cell phenotype. An adaptive component of NK cell-mediated responses

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12 December 2020

Cytotoxic T cells specifically induce Fas on target cells, thereby facilitating exocytosis-independent induction of apoptosis

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12 December 2020

Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population

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12 December 2020

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling

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12 December 2020

Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity

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12 December 2020

Induction of tumor-specific T cell memory by NK cell–mediated tumor rejection

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12 December 2020

Antigen-dependent release of IFN-gamma by cytotoxic T cells up-regulates Fas on target cells and facilitates exocytosis-independent specific target cell lysis

1 reference

12 December 2020

Granzymes are essential for natural killer cell-mediated and perf-facilitated tumor control

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12 December 2020

Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation

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12 December 2020

Functional expression and release of ligands for the activating immunoreceptor NKG2D in leukemia

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12 December 2020

Enhanced antitumor immunity in mice deficient in CD69.

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12 December 2020

Apoptosis, TGF beta and transfusion-related immunosuppression: Biologic versus clinical effects

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12 December 2020

Regulation of perforin‐independent NK cell‐mediated cytotoxicity

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12 December 2020

Natural Killer Cells Activated by MHC Class ILow Targets Prime Dendritic Cells to Induce Protective CD8 T Cell Responses

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12 December 2020

Differential implication of protein kinase C isoforms in cytotoxic T lymphocyte degranulation and TCR-induced Fas ligand expression

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12 December 2020

Abl-kinase-sensitive levels of ERK5 and its intrinsic basal activity contribute to leukaemia cell survival

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12 December 2020

Multifunctional role of Erk5 in multiple myeloma

1 reference

12 December 2020

A T lymphocyte-specific transcription complex containing RUNX1 activates MHC class I expression

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12 December 2020

Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion

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12 December 2020

Regulation of cellular functions by the ERK5 signalling pathway

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12 December 2020

Class-, gene-, and group-specific HLA silencing by lentiviral shRNA delivery

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12 December 2020

Function of natural killer cells in immune defence against human leukaemia

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12 December 2020

Novel approaches using natural killer cells in cancer therapy

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12 December 2020

Positive and negative regulation of Natural Killer cells: therapeutic implications

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12 December 2020

Analyses and perspectives in cancer immunotherapy

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12 December 2020

Interferons, immunity and cancer immunoediting

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12 December 2020

ERK5 activates NF-kappaB in leukemic T cells and is essential for their growth in vivo.

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12 December 2020

Comprehensive analysis of homeobox genes in Hodgkin lymphoma cell lines identifies dysregulated expression of HOXB9 mediated via ERK5 signaling and BMI1.

1 reference

12 December 2020

Regulating MHC expression for cellular therapeutics

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12 December 2020

MHC class I antigens and immune surveillance in transformed cells.

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12 December 2020

Natural killer cell alloreactivity in allogeneic hematopoietic transplantation.

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12 December 2020

Downregulation of microRNAs-143 and -145 in B-cell malignancies

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12 December 2020

Natural killer cell-directed therapies: moving from unexpected results to successful strategies

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12 December 2020

Up on the tightrope: natural killer cell activation and inhibition

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12 December 2020

Functions of natural killer cells

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12 December 2020

Treatment of metastatic melanoma with an autologous tumor-cell vaccine: clinical and immunologic results in 64 patients

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12 December 2020

In vivo effect of anti-asialo GM1 antibody on natural killer activity

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12 December 2020

Heterologous expression of adenovirus E3-gp19K in an E1a-deleted adenovirus vector inhibits MHC I expression in vitro, but does not prolong transgene expression in vivo

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12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.0803006

1 reference

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22 January 2020

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22 January 2020

PubMed publication ID

19265117

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