Protein load impairs factor H binding promoting complement-dependent dysfunction of proximal tubular cells (Q39879961)

15 September 2017

title

Protein load impairs factor H binding promoting complement-dependent dysfunction of proximal tubular cells (English)

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15 September 2017

10

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15 September 2017

9

Peter F Zipfel

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15 September 2017

Simona Buelli

1

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15 September 2017

Mauro Abbate

2

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15 September 2017

Marina Morigi

3

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15 September 2017

Daniela Moioli

4

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15 September 2017

Cristina Zanchi

5

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15 September 2017

Marina Noris

6

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15 September 2017

Carla Zoja

7

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15 September 2017

Charles D Pusey

8

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15 September 2017

language of work or name

English

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publication date

25 February 2009

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15 September 2017

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15 September 2017

volume

75

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15 September 2017

issue

10

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15 September 2017

page(s)

1050-1059

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Pathophysiology of Progressive Nephropathies

15 September 2017

cites work

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7 January 2021

The future of renoprotection

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7 January 2021

Proximal tubular cell synthesis and secretion of endothelin-1 on challenge with albumin and other proteins

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7 January 2021

Protein overload stimulates RANTES production by proximal tubular cells depending on NF-kappa B activation.

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7 January 2021

Regulation of endothelin-1 and transforming growth factor-beta1 production in cultured proximal tubular cells by albumin and heparan sulphate glycosaminoglycans

1 reference

7 January 2021

Protein overload induces fractalkine upregulation in proximal tubular cells through nuclear factor kappaB- and p38 mitogen-activated protein kinase-dependent pathways

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7 January 2021

Proteinuria and damage to tubular cells--is complement a culprit?

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7 January 2021

Intrarenal synthesis of complement.

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7 January 2021

Transferrin but not albumin mediates stimulation of complement C3 biosynthesis in human proximal tubular epithelial cells

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7 January 2021

Complement inhibitors targeted to the proximal tubule prevent injury in experimental nephrotic syndrome and demonstrate a key role for C5b-9

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7 January 2021

Proximal tubular cells promote fibrogenesis by TGF-beta1-mediated induction of peritubular myofibroblasts

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7 January 2021

Complement-mediated dysfunction of glomerular filtration barrier accelerates progressive renal injury

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7 January 2021

C5b-9 does not mediate chronic tubulointerstitial disease in the absence of proteinuria.

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7 January 2021

Alternative pathway activation of complement by cultured human proximal tubular epithelial cells.

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7 January 2021

Alternative pathway complement activation induces proinflammatory activity in human proximal tubular epithelial cells

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7 January 2021

Interferon-gamma induces biosynthesis of complement components C2, C4 and factor H by human proximal tubular epithelial cells

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7 January 2021

Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome

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7 January 2021

Binding of complement factor H to endothelial cells is mediated by the carboxy-terminal glycosaminoglycan binding site

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7 January 2021

How does proteinuria cause progressive renal damage?

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7 January 2021

The C-terminus of complement regulator Factor H mediates target recognition: evidence for a compact conformation of the native protein

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7 January 2021

Regulation of alternative pathway complement activation by glycosaminoglycans: specificity of the polyanion binding site on factor H

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7 January 2021

Heparanase in glomerular diseases

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7 January 2021

The membrane attack complex, C5b-9, up regulates collagen gene expression in renal tubular epithelial cells.

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7 January 2021

C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion

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7 January 2021

Factor H and disease: a complement regulator affects vital body functions.

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7 January 2021

Complement regulatory proteins in glomerular diseases

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7 January 2021

Factor H binds to washed human platelets.

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7 January 2021

Release of endogenous anti-inflammatory complement regulators FHL-1 and factor H protects synovial fibroblasts during rheumatoid arthritis

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7 January 2021

Discrimination between activators and nonactivators of the alternative pathway of complement: regulation via a sialic acid/polyanion binding site on factor H

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7 January 2021

Complement C3b/C3d and cell surface polyanions are recognized by overlapping binding sites on the most carboxyl-terminal domain of complement factor H

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7 January 2021

Complement and diseases: defective alternative pathway control results in kidney and eye diseases

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7 January 2021

Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H

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7 January 2021

HK-2: an immortalized proximal tubule epithelial cell line from normal adult human kidney

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7 January 2021

Pathophysiology of disease progression in proteinuric nephropathies

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7 January 2021

Albumin stimulates interleukin-8 expression in proximal tubular epithelial cells in vitro and in vivo

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7 January 2021

Identifiers

DOI

10.1038/KI.2009.8

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release_krq3cnntkrgzziztt43yijhece

15 September 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/krq3cnntkrgzziztt43yijhece

24 November 2022

mapped directly with Wikidata item

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