Identification of multidrug and toxin extrusion (MATE1 and MATE2-K) variants with complete loss of transport activity. (Q39892581)

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20 January 2020

title

Identification of multidrug and toxin extrusion (MATE1 and MATE2-K) variants with complete loss of transport activity (English)

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20 January 2020

3

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20 January 2020

author name string

Moto Kajiwara

1

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20 January 2020

Tomohiro Terada

2

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20 January 2020

Junko Iwano

4

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20 January 2020

Toshiya Katsura

5

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20 January 2020

Atsushi Fukatsu

6

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20 January 2020

Toshio Doi

7

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20 January 2020

Ken-ichi Inui

8

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publication date

9 January 2009

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Journal of Human Genetics

20 January 2020

published in

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20 January 2020

volume

54

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20 January 2020

issue

1

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page(s)

40-46

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Cellular and molecular aspects of drug transport in the kidney

20 January 2020

cites work

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MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs

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A human transporter protein that mediates the final excretion step for toxic organic cations

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Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2.

21 January 2018

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Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects

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The genetic polymorphism of drug transporters: functional analysis approaches.

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Influence of drug transporter polymorphisms on pravastatin pharmacokinetics in humans

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Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics

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Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action

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Genetic variants of the organic cation transporter 2 influence the disposition of metformin

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Variability in renal clearance of substrates for renal transporters in chinese subjects

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Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters

21 January 2018

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Critical roles of Sp1 in gene expression of human and rat H+/organic cation antiporter MATE1

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Physiological and pharmacokinetic roles of H+/organic cation antiporters (MATE/SLC47A).

21 January 2018

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Non-synonymous polymorphisms in the human SLCO1B1 gene: an in vitro analysis of SNP c.1929A>C.

21 January 2018

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Human organic cation transporter (OCT1 and OCT2) gene polymorphisms and therapeutic effects of metformin.

21 January 2018

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Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.

21 January 2018

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Differential contribution of organic cation transporters, OCT2 and MATE1, in platinum agent-induced nephrotoxicity

21 January 2018

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Mechanisms mediating renal secretion of organic anions and cations

21 January 2018

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7 January 2021

Transport of organic anions across the basolateral membrane of proximal tubule cells

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7 January 2021

Multidrug resistance-associated protein 4 is involved in the urinary excretion of hydrochlorothiazide and furosemide

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7 January 2021

Involvement of MRP4 (ABCC4) in the luminal efflux of ceftizoxime and cefazolin in the kidney

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7 January 2021

Oppositely directed H+ gradient functions as a driving force of rat H+/organic cation antiporter MATE1

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7 January 2021

Molecular cloning, functional characterization and tissue distribution of rat H+/organic cation antiporter MATE1

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7 January 2021

Identification of essential histidine and cysteine residues of the H+/organic cation antiporter multidrug and toxin extrusion (MATE)

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7 January 2021

Cisplatin and oxaliplatin, but not carboplatin and nedaplatin, are substrates for human organic cation transporters (SLC22A1-3 and multidrug and toxin extrusion family)

1 reference

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7 January 2021

Identifiers

DOI

10.1038/JHG.2008.1

1 reference

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release_xdco42yphfbk5kgcwgmqz4qp5a

20 January 2020

Fatcat ID

0 references

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