Morphologic and functional correlates of synaptic pathology in the cathepsin D knockout mouse model of congenital neuronal ceroid lipofuscinosis (Q39898507)

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English	Morphologic and functional correlates of synaptic pathology in the cathepsin D knockout mouse model of congenital neuronal ceroid lipofuscinosis	scientific article

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scholarly article

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Europe PubMed Central

15 September 2017

Morphologic and functional correlates of synaptic pathology in the cathepsin D knockout mouse model of congenital neuronal ceroid lipofuscinosis (English)

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Europe PubMed Central

15 September 2017

congenital disorder

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Jonathan D. Cooper

5

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Europe PubMed Central

15 September 2017

Thomas H. Gillingwater

7

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Europe PubMed Central

15 September 2017

Svetlana Molchanova

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Svetlana M Molchanova

2

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Jaana Tyynelä-Vesterinen

8

object named as

Jaana Tyynelä

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Europe PubMed Central

15 September 2017

author name string

Sabine Koch

1

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Europe PubMed Central

15 September 2017

Ann K Wright

3

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Europe PubMed Central

15 September 2017

Andrew Edwards

4

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Europe PubMed Central

15 September 2017

Tomi Taira

6

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Europe PubMed Central

15 September 2017

publication date

1 December 2011

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Europe PubMed Central

15 September 2017

Journal of Neuropathology & Experimental Neurology

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Europe PubMed Central

15 September 2017

70

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Europe PubMed Central

15 September 2017

12

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Europe PubMed Central

15 September 2017

1089-1096

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15 September 2017

describes a project that uses

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3242052/fullTextXML

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CHMP2B mutants linked to frontotemporal dementia impair maturation of dendritic spines.

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22 September 2017

Molecular correlates of axonal and synaptic pathology in mouse models of Batten disease

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Ube3a is required for experience-dependent maturation of the neocortex.

1 reference

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22 September 2017

Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

22 September 2017

Towards understanding the neuronal ceroid lipofuscinoses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

22 September 2017

Palmitoyl protein thioesterase-1 deficiency impairs synaptic vesicle recycling at nerve terminals, contributing to neuropathology in humans and mice

1 reference

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22 September 2017

Capabilities of the WinLTP data acquisition program extending beyond basic LTP experimental functions

1 reference

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22 September 2017

Synaptic vulnerability in neurodegenerative disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

22 September 2017

Progressively reduced synaptic vesicle pool size in cultured neurons derived from neuronal ceroid lipofuscinosis-1 knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

22 September 2017

Early changes in Huntington's disease patient brains involve alterations in cytoskeletal and synaptic elements

1 reference

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22 September 2017

A focus on the synapse for neuroprotection in Alzheimer disease and other dementias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

22 September 2017

Short-term synaptic plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

22 September 2017

A mutation in the ovine cathepsin D gene causes a congenital lysosomal storage disease with profound neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

22 September 2017

Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

22 September 2017

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1 reference

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22 September 2017

Cathepsin D deficiency underlies congenital human neuronal ceroid-lipofuscinosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

15 June 2018

Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

15 June 2018

Heterogeneity of release probability, facilitation, and depletion at central synapses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

15 June 2018

Murine cathepsin D deficiency is associated with dysmyelination/myelin disruption and accumulation of cholesteryl esters in the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

20 August 2018

Novel mutation and the first prenatal screening of cathepsin D deficiency (CLN10).

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

20 August 2018

Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

20 August 2018

In vivo MRI reveals the dynamics of pathological changes in the brains of cathepsin D-deficient mice and correlates changes in manganese-enhanced MRI with microglial activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

20 August 2018

Delayed synaptic degeneration in the CNS of Wlds mice after cortical lesion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

20 August 2018

Functional maturation of CA1 synapses involves activity-dependent loss of tonic kainate receptor-mediated inhibition of glutamate release.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

20 August 2018

A mutation in the cathepsin D gene (CTSD) in American Bulldogs with neuronal ceroid lipofuscinosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

20 August 2018

Proteolytic degradation of glutamate decarboxylase mediates disinhibition of hippocampal CA3 pyramidal cells in cathepsin D-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

20 August 2018

Cathepsin D-deficient Drosophila recapitulate the key features of neuronal ceroid lipofuscinoses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

20 August 2018

Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

20 August 2018

Release probability is regulated by the size of the readily releasable vesicle pool at excitatory synapses in hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

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Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice.

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20 August 2018

Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: a combined retrograde tracing and immunocytochemical study in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

20 August 2018

Neuronal ceroid lipofuscinoses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

1 October 2018

Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242052

4 November 2018

Synaptic Changes in the Thalamocortical System of Cathepsin D-Deficient Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22082660

12 December 2020

based on heuristic

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Synapse loss associated with abnormal PrP precedes neuronal degeneration in the scrapie-infected murine hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/22082660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Congenital neuronal ceroid lipofuscinosis. A case report

1 reference

https://pubmed.ncbi.nlm.nih.gov/22082660

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1097/NEN.0B013E318238FC28

1 reference

Europe PubMed Central

15 September 2017

1 reference

Europe PubMed Central

15 September 2017

1 reference

Europe PubMed Central

15 September 2017

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