Hsp70 translocates to the nuclei and nucleoli, binds to XRCC1 and PARP-1, and protects HeLa cells from single-strand DNA breaks. (Q39904287)

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18 January 2020

title

Hsp70 translocates to the nuclei and nucleoli, binds to XRCC1 and PARP-1, and protects HeLa cells from single-strand DNA breaks (English)

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18 January 2020

6

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18 January 2020

author name string

Polychronis Kotoglou

1

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18 January 2020

Alexandros Kalaitzakis

2

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18 January 2020

Patra Vezyraki

3

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18 January 2020

Theodore Tzavaras

4

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18 January 2020

Lampros K Michalis

5

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18 January 2020

Jae U Jung

7

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18 January 2020

Charalampos Angelidis

8

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18 January 2020

publication date

17 December 2008

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18 January 2020

published in

Cell Stress & Chaperones

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18 January 2020

volume

14

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18 January 2020

issue

4

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18 January 2020

page(s)

391-406

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Guidelines for the nomenclature of the human heat shock proteins

18 January 2020

cites work

1 reference

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The viral SV40 T antigen cooperates with dj2 to enhance hsc70 chaperone function

22 September 2017

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XRCC1 interactions with base excision repair DNA intermediates

22 September 2017

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Heat shock protein 70 enhanced deoxyribonucleic acid base excision repair in human leukemic cells after ionizing radiation

22 September 2017

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22 September 2017

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Overexpressed heat shock protein 70 protects cells against DNA damage caused by ultraviolet C in a dose-dependent manner

22 September 2017

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Molecular chaperones and protein quality control

22 September 2017

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22 September 2017

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22 September 2017

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Functional interaction between poly(ADP-Ribose) polymerase 2 (PARP-2) and TRF2: PARP activity negatively regulates TRF2.

22 September 2017

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Heat shock protein 70 stimulation of the deoxyribonucleic acid base excision repair enzyme polymerase beta

22 September 2017

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Overexpression of HSP70 is induced by ionizing radiation in C3H 10T1/2 cells and protects from DNA damage

22 September 2017

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Poly(ADP-Ribose) Polymerase 1 and Ste20-Like Kinase hKFC Act as Transcriptional Repressors for Gamma-2 Herpesvirus Lytic Replication

22 September 2017

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Endosomal and lysosomal effects of desferrioxamine: protection of HeLa cells from hydrogen peroxide-induced DNA damage and induction of cell-cycle arrest.

22 September 2017

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Phosphopeptide Binding Specificities of BRCA1 COOH-terminal (BRCT) Domains

22 September 2017

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The budding yeast Rad9 checkpoint complex: chaperone proteins are required for its function

22 September 2017

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XRCC1 and DNA strand break repair

22 September 2017

1 reference

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Aberrant protein folding as the molecular basis of cancer

22 September 2017

1 reference

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The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation.

22 September 2017

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Heat-induced formation of reactive oxygen species and 8-oxoguanine, a biomarker of damage to DNA.

22 September 2017

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Dynamic changes in the localization of thermally unfolded nuclear proteins associated with chaperone-dependent protection

22 September 2017

1 reference

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HSC70 interactions with SV40 viral proteins differ between permissive and nonpermissive mammalian cells

22 September 2017

1 reference

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The molecular chaperone DnaJ is required for the degradation of a soluble abnormal protein in Escherichia coli

22 September 2017

1 reference

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The BRCA1 C-terminal domain: structure and function.

22 September 2017

1 reference

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Structure of an XRCC1 BRCT domain: a new protein-protein interaction module

22 September 2017

1 reference

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XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage

22 September 2017

1 reference

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XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro

22 September 2017

1 reference

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Regulation of the heat-shock protein 70 reaction cycle by the mammalian DnaJ homolog, Hsp40.

22 September 2017

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Identification of the peptide binding domain of hsc70. 18-Kilodalton fragment located immediately after ATPase domain is sufficient for high affinity binding

22 September 2017

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Transgenic mice expressing the human heat shock protein 70 have improved post-ischemic myocardial recovery

22 September 2017

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Location of Ribosomal DNA in the Human Chromosome Complement

22 September 2017

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Expression of human HSP70 during the synthetic phase of the cell cycle

22 September 2017

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22 September 2017

The heat-shock proteins

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A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins

22 September 2017

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Mutational analysis of the human HSP70 protein: distinct domains for nucleolar localization and adenosine triphosphate binding

22 September 2017

1 reference

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Three-dimensional structure of the ATPase fragment of a 70K heat-shock cognate protein

22 September 2017

1 reference

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Heat shock, stress proteins, chaperones, and proteotoxicity

22 September 2017

1 reference

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Heat shock treatment of macrophages causes increased release of superoxide anion

22 September 2017

1 reference

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Heterogeneous patterns of constitutive and heat shock induced expression of HLA-linked HSP70-1 and HSP70-2 heat shock genes in human melanoma cell lines

22 September 2017

1 reference

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Heat shock proteins increase resistance to apoptosis.

25 September 2017

1 reference

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DNA ligase IV binds to XRCC4 via a motif located between rather than within its BRCT domains

25 September 2017

1 reference

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Methods used to study structure and function of the nucleolus

15 June 2018

1 reference

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The kinetics of repair of oxidative DNA damage (strand breaks and oxidised pyrimidines) in human cells.

15 June 2018

1 reference

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70K heat shock related proteins stimulate protein translocation into microsomes.

15 June 2018

1 reference

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Interaction of Hsp 70 with newly synthesized proteins: implications for protein folding and assembly.

15 June 2018

1 reference

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The zinc fingers of human poly(ADP-ribose) polymerase are differentially required for the recognition of DNA breaks and nicks and the consequent enzyme activation. Other structures recognize intact DNA.

15 June 2018

1 reference

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Constitutive expression of heat-shock protein 70 in mammalian cells confers thermoresistance

15 June 2018

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Isolation and purification of nucleoli and nucleolar chromatin from mammalian cells

15 June 2018

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Molecular chaperones and the stress of oncogenesis

15 June 2018

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The inner nuclear membrane protein lamin B receptor forms distinct microdomains and links epigenetically marked chromatin to the nuclear envelope.

20 August 2018

1 reference

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Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice

20 August 2018

1 reference

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Specific inhibition of simian virus 40 protein synthesis by heat and arsenite treatment

20 August 2018

1 reference

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Mydj2 as a potent partner of hsc70 in mammalian cells

20 August 2018

1 reference

12 December 2020

Heat shock protein 70 chaperone overexpression ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model by reducing nuclear-localized mutant androgen receptor protein

1 reference

12 December 2020

Nuclear and nucleolar localization of the 72,000-dalton heat shock protein in heat-shocked mammalian cells

1 reference

12 December 2020

Involvement of heat shock protein-70 in the mechanism of hydrogen peroxide-induced DNA damage: the role of lysosomes and iron

1 reference

12 December 2020

Expression of hsp70 induced in CHO cells by 45.0 degrees C hyperthermia is cell cycle associated and DNA synthesis dependent

1 reference

12 December 2020

Effect of nucleotides, peptides, and unfolded proteins on the self-association of the molecular chaperone HSC70

1 reference

12 December 2020

Aggregation of hsp70 and hsc70 in vivo is distinct and temperature-dependent and their chaperone function is directly related to non-aggregated forms

1 reference

12 December 2020

Holding damaged DNA together

1 reference

12 December 2020

10.1007/S12192-008-0093-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19089598%20AND%20SRC:MED&resulttype=core&format=json

release_37yzfbu3s5egdjbfhyfuufhtdi

18 January 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/37yzfbu3s5egdjbfhyfuufhtdi

24 November 2022

mapped directly with Wikidata item

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18 January 2020

PubMed publication ID

19089598

1 reference