Protein kinase C theta (PKCtheta)-dependent phosphorylation of PDK1 at Ser504 and Ser532 contributes to palmitate-induced insulin resistance (Q39910455)

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English	Protein kinase C theta (PKCtheta)-dependent phosphorylation of PDK1 at Ser504 and Ser532 contributes to palmitate-induced insulin resistance	scientific article

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scholarly article

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Europe PubMed Central

15 September 2017

Protein kinase C theta (PKCtheta)-dependent phosphorylation of PDK1 at Ser504 and Ser532 contributes to palmitate-induced insulin resistance (English)

1 reference

Europe PubMed Central

15 September 2017

phosphorylation

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insulin resistance

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based on heuristic

inferred from title

author name string

Changhua Wang

1

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Europe PubMed Central

15 September 2017

Meilian Liu

2

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Europe PubMed Central

15 September 2017

Ramon A Riojas

3

1 reference

Europe PubMed Central

15 September 2017

Xiaoban Xin

4

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Europe PubMed Central

15 September 2017

Zhanguo Gao

5

1 reference

Europe PubMed Central

15 September 2017

Rong Zeng

6

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Europe PubMed Central

15 September 2017

Jiarui Wu

7

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Europe PubMed Central

15 September 2017

Lily Q Dong

8

1 reference

Europe PubMed Central

15 September 2017

Feng Liu

9

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Europe PubMed Central

15 September 2017

language of work or name

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publication date

1 December 2008

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Europe PubMed Central

15 September 2017

number of pages

7

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Journal of Biological Chemistry

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15 September 2017

284

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15 September 2017

4

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Europe PubMed Central

15 September 2017

2038-2044

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Europe PubMed Central

15 September 2017

Measurement of plasma glucose, free fatty acid, lactate, and insulin for 24 h in patients with NIDDM.

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https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

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https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Substitution of the autophosphorylation site Thr516 with a negatively charged residue confers constitutive activity to mouse 3-phosphoinositide-dependent protein kinase-1 in cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Altered insulin signaling in retinal tissue in diabetic states

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Rescue of TNFalpha-inhibited neuronal cells by IGF-1 involves Akt and c-Jun N-terminal kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascade

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https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex.

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https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Primary structure, tissue distribution, and expression of mouse phosphoinositide-dependent protein kinase-1, a protein kinase that phosphorylates and activates protein kinase Czeta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Mouse 3-phosphoinositide-dependent protein kinase-1 undergoes dimerization and trans-phosphorylation in the activation loop

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https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

PDGF signaling in cells and mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Protein kinase Ctheta expression is increased upon differentiation of human skeletal muscle cells: dysregulation in type 2 diabetic patients and a possible role for protein kinase Ctheta in insulin-stimulated glycogen synthase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

PKCtheta is a key player in the development of insulin resistance

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https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

IRS1-independent defects define major nodes of insulin resistance

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https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

PDK1 regulates cell proliferation and cell cycle progression through control of cyclin D1 and p27Kip1 expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

PKC-theta knockout mice are protected from fat-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Mechanisms of insulin resistance and new pharmacological approaches to metabolism and diabetic complications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Tissue and isoform-selective activation of protein kinase C in insulin-resistant obese Zucker rats - effects of feeding.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Role of insulin in the pathogenesis of free fatty acid-induced insulin resistance in skeletal muscle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806336200

21 January 2018

Identifiers

10.1074/JBC.M806336200

1 reference

Europe PubMed Central

15 September 2017

1 reference

Europe PubMed Central

15 September 2017

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