Global target profile of the kinase inhibitor bosutinib in primary chronic myeloid leukemia cells (Q39911338)

15 September 2017

Global target profile of the kinase inhibitor bosutinib in primary chronic myeloid leukemia cells (English)

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15 September 2017

chronic myeloid leukemia

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bosutinib

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ChEBI release 2020-05-28

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12

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O Hantschel

4

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author name string

L L Remsing Rix

1

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U Rix

2

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J Colinge

3

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K L Bennett

5

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T Stranzl

6

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15 September 2017

A Müller

7

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C Baumgartner

8

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P Valent

9

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M Augustin

10

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J H Till

11

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27 November 2008

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23

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3

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477-485

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https://scigraph.springernature.com/pub.10.1038/leu.2008.334

15 September 2017

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Current and emerging treatment options in chronic myeloid leukemia

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Flying under the radar: the new wave of BCR-ABL inhibitors

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In vitro and in vivo activity of SKI-606, a novel Src-Abl inhibitor, against imatinib-resistant Bcr-Abl+ neoplastic cells

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SKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells

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Effective and selective inhibition of chronic myeloid leukemia primitive hematopoietic progenitors by the dual Src/Abl kinase inhibitor SKI-606.

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Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

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A small molecule-kinase interaction map for clinical kinase inhibitors

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Target spectrum of the BCR-ABL inhibitors imatinib, nilotinib and dasatinib

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Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets

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AXL is a potential target for therapeutic intervention in breast cancer progression.

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The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

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Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling.

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Activated Ca2+/calmodulin-dependent protein kinase IIgamma is a critical regulator of myeloid leukemia cell proliferation

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3D-QSAR studies on c-Src kinase inhibitors and docking analyses of a potent dual kinase inhibitor of c-Src and c-Abl kinases

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Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

21 January 2018

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Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation

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TNK2 preserves epidermal growth factor receptor expression on the cell surface and enhances migration and invasion of human breast cancer cells

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BCR/ABL kinase inhibition by imatinib mesylate enhances MAP kinase activity in chronic myelogenous leukemia CD34+ cells

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Biosignaling of mammalian Ste20-related kinases

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The GCK II and III subfamilies of the STE20 group kinases.

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The dark side of the NGF family: neurotrophins in neoplasias

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Cytogenetics of the chronic myeloid leukemia-derived cell line K562: karyotype clarification by multicolor fluorescence in situ hybridization, comparative genomic hybridization, and locus-specific fluorescence in situ hybridization

21 January 2018

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Comparison of competitive-nested PCR and real-time PCR in detecting BCR-ABL fusion transcripts in chronic myeloid leukemia patients

21 January 2018

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Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer

21 January 2018

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EGFR antagonists in cancer treatment

21 January 2018

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The tyrosine kinase FES is an essential effector of KITD816V proliferation signal

21 January 2018

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Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias

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Circumventing Resistance to Kinase-Inhibitor Therapy

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Imatinib as a paradigm of targeted therapies

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inferred from DOI database lookup

7 January 2021

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Identifiers

DOI

10.1038/LEU.2008.334

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Dimensions Publication ID

15 September 2017

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1 reference