Graded levels of FGF protein span the midbrain and can instruct graded induction and repression of neural mapping labels (Q39918145)

15 September 2017

Graded levels of FGF protein span the midbrain and can instruct graded induction and repression of neural mapping labels (English)

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15 September 2017

2

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15 September 2017

Yao Chen

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15 September 2017

John G Flanagan

series ordinal

3

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15 September 2017

language of work or name

English

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publication date

1 June 2009

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15 September 2017

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15 September 2017

62

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15 September 2017

6

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15 September 2017

773-780

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describes a project that uses

15 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2850284/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning

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Specific regions within the embryonic midbrain and cerebellum require different levels of FGF signaling during development.

22 September 2017

1 reference

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Development of continuous and discrete neural maps

22 September 2017

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Rethinking the proximodistal axis of the vertebrate limb in the molecular era

22 September 2017

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FGF signalling pathways in development of the midbrain and anterior hindbrain

22 September 2017

1 reference

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Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism

22 September 2017

1 reference

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Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family

22 September 2017

1 reference

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Neural map specification by gradients

22 September 2017

1 reference

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Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain

22 September 2017

1 reference

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Molecular gradients and development of retinotopic maps

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Opposing gradients of ephrin-As and EphA7 in the superior colliculus are essential for topographic mapping in the mammalian visual system

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

How does Fgf signaling from the isthmic organizer induce midbrain and cerebellum development?

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Divide et Impera--the midbrain-hindbrain boundary and its organizer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Diverse roles of eph receptors and ephrins in the regulation of cell migration and tissue assembly

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Spatial and temporal expression of heparan sulfate in mouse development regulates FGF and FGF receptor assembly

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Mammalian Brain Morphogenesis and Midline Axon Guidance Require Heparan Sulfate

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Generating the cerebral cortical area map

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

CHEMOAFFINITY IN THE ORDERLY GROWTH OF NERVE FIBER PATTERNS AND CONNECTIONS

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

FGFR1 is independently required in both developing mid- and hindbrain for sustained response to isthmic signals

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

A re-examination of proximodistal patterning during vertebrate limb development

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Functions of FGF signalling from the apical ectodermal ridge in limb development

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Ephrin-As as receptors in topographic projections

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

FGFs, heparan sulfate and FGFRs: complex interactions essential for development

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Shared and distinct functions of RAGS and ELF-1 in guiding retinal axons

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Rostral optic tectum acquires caudal characteristics following ectopic engrailed expression

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Positional Information in Chick Limb Morphogenesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Retroviral misexpression of engrailed genes in the chick optic tectum perturbs the topographic targeting of retinal axons

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

FGF signaling and target recognition in the developing Xenopus visual system

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Specifying positional information in the embryo: looking beyond morphogens.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Fgf signals from a novel signaling center determine axial patterning of the prospective neural retina.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Loss-of-function analysis of EphA receptors in retinotectal mapping.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

FGF17b and FGF18 have different midbrain regulatory properties from FGF8b or activated FGF receptors

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Engrailed and Fgf8 act synergistically to maintain the boundary between diencephalon and mesencephalon

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Graded interference with FGF signalling reveals its dorsoventral asymmetry at the mid-hindbrain boundary.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Ephrin-A5 (AL-1/RAGS) is essential for proper retinal axon guidance and topographic mapping in the mammalian visual system.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

En-2 regulates the expression of the ligands for Eph type tyrosine kinases in chick embryonic tectum.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Inhibition of FGF receptor activity in retinal ganglion cell axons causes errors in target recognition

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Midbrain development induced by FGF8 in the chick embryo.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850284

Alkaline phosphatase fusions of ligands or receptors as in situ probes for staining of cells, tissues, and embryos

20 August 2018

1 reference

12 December 2020

Inductive signal and tissue responsiveness defining the tectum and the cerebellum

1 reference

12 December 2020

The Fgf8 signal causes cerebellar differentiation by activating the Ras-ERK signaling pathway

1 reference

12 December 2020

Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate

1 reference

12 December 2020

10.1016/J.NEURON.2009.05.023

Identifiers

DOI

1 reference

15 September 2017

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15 September 2017

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