MR-1 modulates proliferation and migration of human hepatoma HepG2 cells through myosin light chains-2 (MLC2)/focal adhesion kinase (FAK)/Akt signaling pathway (Q39925975)

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scientific article published on 23 October 2008

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English	MR-1 modulates proliferation and migration of human hepatoma HepG2 cells through myosin light chains-2 (MLC2)/focal adhesion kinase (FAK)/Akt signaling pathway	scientific article published on 23 October 2008

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scholarly article

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Europe PubMed Central

PubMed publication ID

15 September 2017

MR-1 modulates proliferation and migration of human hepatoma HepG2 cells through myosin light chains-2 (MLC2)/focal adhesion kinase (FAK)/Akt signaling pathway (English)

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Europe PubMed Central

PubMed publication ID

15 September 2017

hepatocellular carcinoma

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based on heuristic

inferred from title

author name string

Kaihuan Ren

1

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Europe PubMed Central

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15 September 2017

Haixia Jin

2

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15 September 2017

Chunjing Bian

3

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15 September 2017

Hongwei He

4

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15 September 2017

Xia Liu

5

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15 September 2017

Shenghua Zhang

6

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15 September 2017

Yiguang Wang

7

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15 September 2017

Rong-guang Shao

8

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15 September 2017

language of work or name

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publication date

23 October 2008

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15 September 2017

Journal of Biological Chemistry

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15 September 2017

283

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15 September 2017

51

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15 September 2017

35598-35605

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15 September 2017

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Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

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Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion

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Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

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FAK is the upstream signal protein of the phosphatidylinositol 3-kinase-Akt survival pathway in hydrogen peroxide-induced apoptosis of a human glioblastoma cell line

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Cdc42-MRCK and Rho-ROCK signalling cooperate in myosin phosphorylation and cell invasion

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Lamellipodial actin mechanically links myosin activity with adhesion-site formation

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Focal adhesions: paradigm for a signaling nexus

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Myosin light chain kinase plays a role in the regulation of epithelial cell survival

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Increased expression of myosin light chain kinase mRNA is related to metastasis in non-small cell lung cancer.

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Extracellular signal-regulated kinase mediates phosphorylation of tropomyosin-1 to promote cytoskeleton remodeling in response to oxidative stress: impact on membrane blebbing

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21 January 2018

Myosin light chain kinase inhibitors can block invasion and adhesion of human pancreatic cancer cell lines

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FAK integrates growth-factor and integrin signals to promote cell migration

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Identification of Src-specific phosphorylation site on focal adhesion kinase: dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior

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Focal adhesion kinase is required for the spatial organization of the leading edge in migrating cells

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Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

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Identifiers

10.1074/JBC.M802253200

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

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